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All Journal Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Victory O Pangemanan
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Health Professions Nursing Physics Public Health

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Perubahan Berat Badan Mencit (Mus musculus) Model Diabetes Melitus Tipe 1 yang Diterapi Ekstrak Alga Coklat Sargassum sp Abdul M Ukratalo; Giovano Amahoru; Dodikrisno E Manery; Taufik Zuneldi; Victory O Pangemanan; Muhammad Fitrah Loilatu
Jurnal Anestesi Vol. 2 No. 3 (2024): Juli : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v2i3.1102

Abstract

In type 1 diabetes, when the body does not produce enough insulin or none at all. This causes blood glucose levels to remain high while the body's cells are starved for energy. As a result, the body turns to alternative energy sources, namely fat and muscle, leading to weight loss. Sargassum sp contains steroid, alkaloid, phenol, flavonoid, saponin and tannin compounds that can be antioxidant and antidiabetic. This study aims to determine changes in body weight of mice (Mus musculus) type 1 diabetes mellitus models treated with Sargassum sp. This study is an experimental study. Mice were divided into 6 groups, namely KN, K-, K+, P1, P2 and P3. Body weight was weighed on day 0, day 14 (post STZ induction) and day 28 (post drug administration). The data were analysed by ANOVA using SPSS program. The results showed that Sargassum sp extract can increase the body weight of DM mice.
Co-Authors Abdul M Ukratalo Dodikrisno E Manery Giovano Amahoru Muhammad Fitrah Loilatu Taufik Zuneldi