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All Journal Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Dodikrisno E Manery
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Dentistry Health Professions Nursing Physics Public Health Veterinary

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Perubahan Berat Badan Mencit (Mus musculus) Model Diabetes Melitus Tipe 1 yang Diterapi Ekstrak Alga Coklat Sargassum sp Abdul M Ukratalo; Giovano Amahoru; Dodikrisno E Manery; Taufik Zuneldi; Victory O Pangemanan; Muhammad Fitrah Loilatu
Jurnal Anestesi Vol. 2 No. 3 (2024): Juli : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v2i3.1102

Abstract

In type 1 diabetes, when the body does not produce enough insulin or none at all. This causes blood glucose levels to remain high while the body's cells are starved for energy. As a result, the body turns to alternative energy sources, namely fat and muscle, leading to weight loss. Sargassum sp contains steroid, alkaloid, phenol, flavonoid, saponin and tannin compounds that can be antioxidant and antidiabetic. This study aims to determine changes in body weight of mice (Mus musculus) type 1 diabetes mellitus models treated with Sargassum sp. This study is an experimental study. Mice were divided into 6 groups, namely KN, K-, K+, P1, P2 and P3. Body weight was weighed on day 0, day 14 (post STZ induction) and day 28 (post drug administration). The data were analysed by ANOVA using SPSS program. The results showed that Sargassum sp extract can increase the body weight of DM mice.
Gambaran Tingkat Stres Akademik pada Mahasiswa Keperawatan STIKES Pasapua Ambon Tahun 2024 Dodikrisno E Manery; Taufik Zuneldi; Yushar A Embisa; Abdul M Ukratalo; Nadira Pattimura
Jurnal Anestesi Vol. 2 No. 3 (2024): Juli : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v2i3.1228

Abstract

Academic stress is a common issue faced by students, particularly those in demanding programs such as nursing. This study aims to describe the level of academic stress among students at STIKES Pasapua Ambon. The researcher employed a descriptive quantitative method. The sample in this study consisted of 76 individuals. Data were collected by distributing questionnaires or surveys online using Google Forms. Data were analyzed using univariate analysis to provide a descriptive overview The results showed that the majority of respondents were female (68.4%), aged 17-19 years (46.1%), living in dormitories (36.1%), and from outside Ambon Island (68.4%), with academic stress levels falling in the moderate category (48.7%). Given the moderate academic stress experienced by many students, it is important to raise awareness about the importance of mental well-being.
Perilaku Masturbasi di Kalangan Remaja dan Kaitannya dengan Self-Concept Dodikrisno E Manery; Abdul M Ukratalo; Edwin Buranga; Arief Rahman S Kaliky
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3124

Abstract

Masturbation is a common aspect of sexual development in adolescents and plays a role in identity exploration and the formation of self-concept. Adolescence represents a critical developmental phase during which individuals seek to understand their identity, including their body and sexuality. Within a psychosocial context, masturbation may contribute positively to self-concept development when supported by a healthy understanding and an inclusive environment. However, social pressures, religious norms, and cultural values that prohibit or stigmatize masturbation often generate internal conflict, influencing adolescents’ self-perception. The resulting negative self-concept may lead to feelings of shame, guilt, stress, and adverse impacts on mental health. This study aims to examine masturbation behavior among adolescents and its association with negative self-concept. The method employed is a literature review, utilizing both scholarly books and peer-reviewed journal articles. Data collection techniques included gathering literature sources, reading and sorting data, note-taking, identifying relevant findings, and validating the information to support analytical interpretation. Findings indicate that adolescents with a positive self-concept are more capable of accepting their sexual behavior, including masturbation, without excessive guilt or shame. Conversely, those with a negative self-concept are more likely to experience internal conflict that compromises psychological well-being. Factors such as family support, open sexual education, and media influence play a significant role in shaping the relationship between masturbation and self-concept. Comprehensive sexual education can enhance adolescents’ understanding of their bodies and sexuality, thereby reducing stigma and fostering a positive self-concept. In contrast, restrictive and stigmatizing environments tend to worsen self-image and may contribute to anxiety and depression.
Aktivitas Antimalaria Ekstrak Sargassum Duplicatum terhadap Plasmodium Berghei Strain ANKA Secara in Vivo Distance B Maatita; Abdul M Ukratalo; Dodikrisno E Manery
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 2 No. 3 (2024): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v2i3.4129

Abstract

Malaria is a parasitic infection disease caused by Plasmodium and is a global health issue. The search for new antimalarial drugs from natural sources, such as plants, is ongoing to find effective alternatives. Sargassum duplicatum, a brown seaweed, has been known to possess various biological activities; however, its antimalarial potential has not been thoroughly explored. This study aims to evaluate the antimalarial activity of S. duplicatum extract against Plasmodium berghei strain ANKA in vivo in mice. This is an experimental study. A total of 16 mice were divided into 4 groups: a positive control group and groups infected with P. berghei and treated with S. duplicatum extract at doses of 10, 100, and 200 mg/g body weight. Antimalarial activity was measured based on parasitemia levels, percent inhibition, and ED50 values. Parasitemia measurements were taken from day 0 to day 6 after treatment. The results showed that S. duplicatum extract inhibited the growth of P. berghei with parasitemia inhibition percentages of 65.32% at a dose of 10 mg/g body weight, 65.92% at a dose of 100 mg/g body weight, and 86.61% at a dose of 200 mg/g body weight. The ED50 value of S. duplicatum extract was 2.770 mg/kg body weight in mice. The low ED50 value indicates the extract’s potential as a promising antimalarial drug candidate.
Co-Authors Abdul M Ukratalo Arief Rahman S Kaliky Distance B Maatita Edwin Buranga Giovano Amahoru Muhammad Fitrah Loilatu Nadira Pattimura Taufik Zuneldi Victory O Pangemanan Yushar A Embisa