Claim Missing Document
Check
Articles

Found 12 Documents
Search

Perubahan Berat Badan Mencit (Mus musculus) Model Diabetes Melitus Tipe 1 yang Diterapi Ekstrak Alga Coklat Sargassum sp Abdul M Ukratalo; Giovano Amahoru; Dodikrisno E Manery; Taufik Zuneldi; Victory O Pangemanan; Muhammad Fitrah Loilatu
Jurnal Anestesi Vol. 2 No. 3 (2024): Juli : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v2i3.1102

Abstract

In type 1 diabetes, when the body does not produce enough insulin or none at all. This causes blood glucose levels to remain high while the body's cells are starved for energy. As a result, the body turns to alternative energy sources, namely fat and muscle, leading to weight loss. Sargassum sp contains steroid, alkaloid, phenol, flavonoid, saponin and tannin compounds that can be antioxidant and antidiabetic. This study aims to determine changes in body weight of mice (Mus musculus) type 1 diabetes mellitus models treated with Sargassum sp. This study is an experimental study. Mice were divided into 6 groups, namely KN, K-, K+, P1, P2 and P3. Body weight was weighed on day 0, day 14 (post STZ induction) and day 28 (post drug administration). The data were analysed by ANOVA using SPSS program. The results showed that Sargassum sp extract can increase the body weight of DM mice.
Gambaran Tingkat Stres Akademik pada Mahasiswa Keperawatan STIKES Pasapua Ambon Tahun 2024 Dodikrisno E Manery; Taufik Zuneldi; Yushar A Embisa; Abdul M Ukratalo; Nadira Pattimura
Jurnal Anestesi Vol. 2 No. 3 (2024): Juli : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v2i3.1228

Abstract

Academic stress is a common issue faced by students, particularly those in demanding programs such as nursing. This study aims to describe the level of academic stress among students at STIKES Pasapua Ambon. The researcher employed a descriptive quantitative method. The sample in this study consisted of 76 individuals. Data were collected by distributing questionnaires or surveys online using Google Forms. Data were analyzed using univariate analysis to provide a descriptive overview The results showed that the majority of respondents were female (68.4%), aged 17-19 years (46.1%), living in dormitories (36.1%), and from outside Ambon Island (68.4%), with academic stress levels falling in the moderate category (48.7%). Given the moderate academic stress experienced by many students, it is important to raise awareness about the importance of mental well-being.
Profil Kadar Enzim Serum Glutamat Piruvat Transaminase (SGPT) dan Serum Glutamat Oksaloasetat Transaminase (SGOT) Mencit Model Diabetes Melitus Pasca Pemberian Ekstrak Kulit Batang Cinnamomum burmanii Abdul M Ukratalo
Jurnal Anestesi Vol. 2 No. 4 (2024): Oktober : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v2i4.1454

Abstract

Diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia. Prolonged hyperglycemia leads to oxidative stress, which plays a crucial role in causing further complications, including liver damage characterized by increased levels of Serum Glutamate Pyruvate Transaminase (SGPT) and Serum Glutamate Oxaloacetate Transaminase (SGOT). This study aimed to examine the effects of Cinnamomum burmanii bark extract on SGPT and SGOT levels in a mouse model of diabetes mellitus. The research employed an experimental design using a completely randomized design. It consisted of five treatment groups: K- (normal mice), K+ (diabetic mice), P1, P2, and P3 (diabetic mice treated with Cinnamomum burmanii bark extract at doses of 125, 250, and 500 mg/kg BW). Streptozotocin was injected into groups K+, P1, P2, and P3 at a dose of 0.1 ml per mouse for 14 days. If blood glucose levels increased, extracts were administered to groups P1, P2, and P3 according to the predetermined doses for 14 days. On day 28, surgery was performed to collect blood serum for SGPT and SGOT analysis.. The results of the study indicated that Cinnamomum burmanii bark extract could reduce SGPT and SGOT levels in the diabetic mouse model. This demonstrates the potential of Cinnamomum burmanii as a therapeutic agent that may help reduce liver damage often observed in diabetes mellitus
Telemedicine Sebagai Media Konsultasi Layanan Kesehatan Bagi Masyarakat di Wilayah Pesisir Ian R Tofure; Baringga Aurico De Erwada; Abdul M Ukratalo
Jurnal Anestesi Vol. 3 No. 1 (2025): Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v3i1.1549

Abstract

Telemedicine has emerged as an innovative solution for providing healthcare services, particularly in coastal areas that often face limitations in access and medical facilities. In coastal regions, the main challenges include the long distance from healthcare centers, limited infrastructure, and difficulties in accessing adequate medical care. Telemedicine, by utilizing communication technology to deliver remote medical services, offers an effective way to address these barriers. The purpose of this study is to evaluate the implementation of telemedicine as a health consultation medium for communities in coastal regions. The method used is book reference (reference from books and research journals). The data collection techniques employed in this study include gathering literature, reading, sorting data, taking notes, identifying, and validating the accuracy of the data for subsequent use in analysis. The results of the study show that telemedicine has a very strong aspect related to communication. In terms of utility, telemedicine offers a significant solution to the problem of disparities in healthcare services by utilizing communication channels that transform how people interact in the context of healthcare. Through telemedicine, healthcare providers can reach patients located in distant or remote areas, thereby expanding access and improving the quality of care.
Tumbuhan Herbal Sebagai Alternatif Penghambat Bakteri Streptococcus Mutans dalam Terapi Karies Gigi Moch. Diky Alifuddin; Abdul M Ukratalo; Fiyogi Derandy A Tuhumury
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 3 No. 2 (2025): April : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v3i2.1315

Abstract

Dental caries is one of the most common dental health problems worldwide, caused by bacterial activity in the mouth, notably Streptococcus mutans. This bacterium plays a crucial role in tooth demineralization, ultimately leading to tooth decay. The management of dental caries is typically performed through medical procedures, such as dental fillings; however, this method does not prevent the recurrence of caries. One alternative that has gained attention is the use of herbal plants. This article explores using herbal plants as an alternative inhibitor of Streptococcus mutans bacteria in treating dental caries. The writing of this article employs a narrative analysis approach by collecting secondary data from various previous studies. The exploration results show that 33 herbal plants are used as therapies for addressing dental caries, with five plants being the most commonly used: betel leaf, Lantana camara, lime, celery, and ginger. Using herbal plants to inhibit Streptococcus mutans offers promising potential for developing more natural, safe, and affordable treatment methods.
Etnomedisin Tumbuhan Obat oleh Pengobat Tradisional di Negeri Saleman, Maluku Tengah Abdul M Ukratalo
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 2 (2025): April 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i2.4666

Abstract

Saleman Village is endowed with abundant natural resources that can be utilized by the local community, including various types of medicinal plants that grow either naturally or are intentionally cultivated by its inhabitants. Traditional medicine is an alternative treatment and an essential component of the public health system, passed down through generations. This study analyzes the ethnomedicinal knowledge of medicinal plants used by traditional Saleman Village, Central Maluku healers. A qualitative approach was employed, using in-depth interviews with five traditional healers. The collected data were then analyzed using qualitative descriptive methods. The results identified 36 types of medicinal plants from 26 families. The most commonly used plant part was the leaf (45%), with the predominant method of preparation being boiling (69.4%), and the primary mode of use was oral consumption (70.3%). The local knowledge of Saleman's people regarding the utilization of medicinal plants can serve as a foundation for more in-depth pharmacological research. By integrating modern research with local wisdom, the medicinal plants of Saleman Village hold the potential for development into more effective and safer herbal medicines for health.
Aktivitas Farmakologis Ekstrak Kulit Batang dan Buah Garcinia mangostana L. terhadap Percepatan Penyembuhan Luka Sayat pada Mencit (Mus musculus) Abdul M Ukratalo; Martha Kaihena; Efraim Samson
Jurnal Pendidikan Kimia, Fisika dan Biologi Vol. 1 No. 4 (2025): Juli: Jurnal Pendidikan Kimia, Fisika dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jupenkifb.v1i4.425

Abstract

Wounds are damage to body tissues caused by various factors, both external and internal, which can disrupt the normal function of these tissues. Many studies have focused on using natural ingredients as adjunctive therapy to accelerate wound healing. One plant that shows therapeutic potential is Garcinia mangostana L. This study aims to assess the therapeutic potential of Garcinia mangostana L. stem bark and fruit peel extracts in accelerating the healing of mice (Mus musculus) incision wounds. The study used a completely randomized design (CRD) with six treatments and three replicates, namely negative control mice (K-), positive control (K+), groups of mice given fruit peel and stem bark extracts of G. mangostana concentrations of 25, 50, 75 and 100%. All mice were cut with a wound diameter of 1 cm. The wounds were then left for 13 days with an interval of 3 days for measurement. The results showed that the administration of G. mangostana fruit peel and stem bark extracts had an effect in accelerating the healing of mice incision wounds. From these results, Garcinia mangostana L. has the potential as an additional therapy in accelerating wound healing in mice, which can be used as a basis for further research related to its application in humans.
Perilaku Masturbasi di Kalangan Remaja dan Kaitannya dengan Self-Concept Dodikrisno E Manery; Abdul M Ukratalo; Edwin Buranga; Arief Rahman S Kaliky
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3124

Abstract

Masturbation is a common aspect of sexual development in adolescents and plays a role in identity exploration and the formation of self-concept. Adolescence represents a critical developmental phase during which individuals seek to understand their identity, including their body and sexuality. Within a psychosocial context, masturbation may contribute positively to self-concept development when supported by a healthy understanding and an inclusive environment. However, social pressures, religious norms, and cultural values that prohibit or stigmatize masturbation often generate internal conflict, influencing adolescents’ self-perception. The resulting negative self-concept may lead to feelings of shame, guilt, stress, and adverse impacts on mental health. This study aims to examine masturbation behavior among adolescents and its association with negative self-concept. The method employed is a literature review, utilizing both scholarly books and peer-reviewed journal articles. Data collection techniques included gathering literature sources, reading and sorting data, note-taking, identifying relevant findings, and validating the information to support analytical interpretation. Findings indicate that adolescents with a positive self-concept are more capable of accepting their sexual behavior, including masturbation, without excessive guilt or shame. Conversely, those with a negative self-concept are more likely to experience internal conflict that compromises psychological well-being. Factors such as family support, open sexual education, and media influence play a significant role in shaping the relationship between masturbation and self-concept. Comprehensive sexual education can enhance adolescents’ understanding of their bodies and sexuality, thereby reducing stigma and fostering a positive self-concept. In contrast, restrictive and stigmatizing environments tend to worsen self-image and may contribute to anxiety and depression.
Aktivitas Antimalaria Ekstrak Sargassum Duplicatum terhadap Plasmodium Berghei Strain ANKA Secara in Vivo Distance B Maatita; Abdul M Ukratalo; Dodikrisno E Manery
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 2 No. 3 (2024): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v2i3.4129

Abstract

Malaria is a parasitic infection disease caused by Plasmodium and is a global health issue. The search for new antimalarial drugs from natural sources, such as plants, is ongoing to find effective alternatives. Sargassum duplicatum, a brown seaweed, has been known to possess various biological activities; however, its antimalarial potential has not been thoroughly explored. This study aims to evaluate the antimalarial activity of S. duplicatum extract against Plasmodium berghei strain ANKA in vivo in mice. This is an experimental study. A total of 16 mice were divided into 4 groups: a positive control group and groups infected with P. berghei and treated with S. duplicatum extract at doses of 10, 100, and 200 mg/g body weight. Antimalarial activity was measured based on parasitemia levels, percent inhibition, and ED50 values. Parasitemia measurements were taken from day 0 to day 6 after treatment. The results showed that S. duplicatum extract inhibited the growth of P. berghei with parasitemia inhibition percentages of 65.32% at a dose of 10 mg/g body weight, 65.92% at a dose of 100 mg/g body weight, and 86.61% at a dose of 200 mg/g body weight. The ED50 value of S. duplicatum extract was 2.770 mg/kg body weight in mice. The low ED50 value indicates the extract’s potential as a promising antimalarial drug candidate.
Inventory of Medicinal Plants in the Home Gardens of the Residents of Negeri Latu, Amalatu Subdistrict, West Seram Regency Abdul M Ukratalo; Ahmad Ramdani Patty; Suraya Manuputty
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i3.1367

Abstract

The inventory of medicinal plants involves collecting and organizing data regarding natural resources for resource management planning and serving as a database to reveal the potential of plants in a given area. This study aims to inventory the types of medicinal plants found in the home gardens of the residents of Negeri Latu, Amalatu District, West Seram Regency. The data collection methods employed were exploration and descriptive surveys. The gathered data was subsequently analyzed to identify the benefits or uses of the plants based on relevant literature. The results indicate that 57 species of medicinal plants were found in the home gardens of the residents of Negeri Latu. These plants possess various properties, including antidiabetic, antimalarial, anti-inflammatory, antioxidant, anticholesterol, anticancer, antidysentery, analgesic, antipyretic, and mosquito-repellent effects. This finding highlights the significant potential of home gardens in Negeri Latu as a rich natural resource of medicinal plants. The diversity of plant species reflects the local traditional knowledge of utilizing flora as a natural solution to various health issues.