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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) BioEksakta : Jurnal Ilmiah Biologi Unsoed
Safitri, Nuridha Audinia
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Histopatologi Hepar Mencit (Mus musculus) Jantan yang Diberi Air Rebusan Plastik terhadap Antioksidan Alami Safitri, Nuridha Audinia; Atang, Atang; Wibowo, Eko Setio
BioEksakta : Jurnal Ilmiah Biologi Unsoed Vol 4 No 1 (2022): Bioeksakta
Publisher : Fakultas Biologi Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.bioe.2022.4.1.4606

Abstract

Plastic in Indonesian daily life cannot be avoided anymore. Materials for the manufacture of plastic can cause free radicals to the body, thus affecting the immune system. These materials are including phthalates and bisphenol-A (BPA), which commonly called as plasticizers. Free radicals in the body can be inhibited with antioxidants. Antioxidants can be obtained from endogenous (inside the body) and exogenous (outside the body). The purpose of this study was to determine the damage level of liver histopathological structure as the result of plastic boiled water induction towards natural antioxidants feeding on male mice (Mus musculus). This study used an experimental method with a completely randomized design (CRD) consisting of six treatments and five replications for 21 days. The treatments included two control groups and four other groups treated with plastic boiled water and natural antioxidants. The independent variable is natural antioxidants and the dependent variable is the liver histopathology of male mice. The qualitative parameters observed were the liver histopathological structure of male mice is in the state of inflammatory cell infiltration, degeneration, and necrosis. The research data is an overview of the liver histopathological structure of male mice. The obtained data were analyzed using descriptive qualitative analysis method. Oral induction of boiled-plastic water can affect the changes of liver histological structure. Natural antioxidants given in male mice can maintain the tissue structure as the result of boiled-plastic water induction. The results showed the damage level of male mice liver histopathological structure as reversible degeneration.
Frekuensi Karier Streptococcus pneumoniae pada Populasi Dewasa Suku Akit Provinsi Riau Rosdiana, Dani; Veronica, R. Merlinda; Harahap, Sari; Esha, Indi; Mardhatilah, Ashifa; Putri, Nabila; Safitri, Nuridha Audinia; Safari, Dodi; Sarassari, Rosantia; Ilmiawati, Cimi; Elliyanti, Aisyah
Jurnal Ilmu Kedokteran Vol 18, No 2 (2024): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v18i2.2024.137-143

Abstract

Stretococcus pneumoniae (S.pneumoniae) is a commonly colonized in healthy people that potentially to be transmitted directly to other individuals through droplets and as an invasive pathogen. The prevalence/ frequency of S. pneumoniae carriage in children is around 20-60%, while data of carriage’s frequency in adult population is still limited. Akit tribe is a tribe who lives in a group in the coastal rural area of Rupat Island. The high incidence of upper respiratory tract infection among Akit tribe and the location can be risk for S. pneumoniae carriage. Study aimed is to identify the frequency of carriage in the adult population of the Akit tribe. Nasopharyngeal swab was collected from healthy adults, then cultivated on agar media. Colonies suspected as S. pneumoniae then selected, then subjected to optochin test. S. pneumoniae confirmation were using automatic machine VITEK. We reported S. pneumoniae carriage rate was 7.8% (12 of 153 participants) among Akit tribe.
Co-Authors Aisyah Elliyanti Atang, Atang Cimi Ilmiawati, Cimi Dani Rosdiana Eko Setio Wibowo Esha, Indi Harahap, Sari Mardhatilah, Ashifa Putri, Nabila Safari, Dodi Sarassari, Rosantia Veronica, R. Merlinda