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All Journal Medical and Health Science Journal Bali Medical and Wellness Journal
Rooseno, Ratna Rayeni Natasha
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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Conservative Wound Treatment in DMT2 Patients Using Honey Laksmi, Putu Pradnyasanti; Saraswati, Made Ratna; Rooseno, Ratna Rayeni Natasha; Devinta, Made Ratih Santi; Santosa, Agus
Jurnal Ilmu Kesehatan dan Kesehatan Vol 7 No 02 (2023): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v7i02.4645

Abstract

Background : The number of diabetic patients in Indonesia is on the rise. In contrast to typical wounds in non DMT2 patients, chronic wounds in DMT2 patients heal more slowly, which makes it difficult to achieve complete primary wound healing. Thus, surgery is frequently required to achieve optimal healing. Patients' physical condition, age, comorbidities, and financial circumstances such as high medical costs frequently limiting patients from receiving comprehensive care, resulting alternative treatments are required to treat chronic wounds in DMT2 patients whom prefer conventional medications, addressing all circumstances. Honey, in addition to having fructose compounds, which has the benefit of increasing glucose homeostasis and insulin response, resulting in lower insulin and plasma glucose levels, also has been shown to contain anti-inflammatory and antimicrobial substances that aid in wound healing. Thus, it may be an alternative therapy for chronic wound in DMT2 patients. Methods : A Case-series studies of four DMT2 patients who were referred to Plastic and Reconstructive Outpatient ward with chronic wound were evaluated on a monthly basis following conservative treatment using Nusantara local honey-coated gauze. Result : Secondary wound healing, which can be assessed from the epithelialization process started from the peri-wound area has been obtained through monthly observations. Conclusion : Honey is used as an alternative therapy for patients with diabetic foot ulcers due to its anti-microbial and anti-inflammatory properties in the wound healing process. Furthermore, honey is considered less expensive and more affordable alternative for patients with co-morbidities that is impossible to operate, or with financial limitations. Keywords: DMT2, Chronic wound, Honey
The Comparison of Non-Silver-Based Treatment vs Silver-Based Treatment in Pediatric Burns: Meta-Analysis and Systematic Review Yatindra, Ida Ayu Cempaka Dewi; Rooseno, Ratna Rayeni Natasha; Tiaraningrum, R.Ratu Kania; Dharmawan, Made Surya
Bali Medical and Wellness Journal Vol. 1 No. 2 (2024): Bali Medical and Wellness Journal
Publisher : PT BMW Journal Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71341/bmwj.v1i2.14

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Background: Pediatric burn injuries are a significant global concern, caused by factors such as child maltreatment, fire accidents, and scalding. Effective treatment aims to enhance wound healing and re-epithelialization. Silver-based treatments are a standard approach for burn wounds, but new alternatives may offer improved outcomes. Objective: This study conducts a meta-analysis and systematic review to compare silver and non-silver treatments in pediatric burn care. Methods: A comprehensive literature review and meta-analysis were conducted using the PRISMA guidelines. Data from PubMed, Cochrane Library, and ScienceDirect were utilized. The study focused on children with burn injuries, comparing non-silver treatments (intervention) against silver treatments (control) and assessing outcomes like wound healing, dressing frequency, hospital stay length, complications, graft needs, and pain. Results: The review included 12 randomized controlled trials with 719 participants. Silver treatments served as controls against various non-silver options. Although many trials showed bias and varied quality, results indicated that non-silver treatments led to faster wound healing (mean difference: -0.86 days; 95% CI: −1.26, −0.46; p < 0.0001), fewer dressing changes (mean difference: -2.07 times; 95% CI: -3.39, -0.75; p = 0.0002), and reduced hospital stays (mean difference: −0.76 days; 95% CI: −1.57, 0.05; p = 0.07). No significant differences were found in infection rates or graft needs. Conclusion: Non-silver treatments in pediatric burns result in faster healing, fewer dressings, and shorter hospital stays compared to silver treatments. Further large-scale studies are necessary to confirm these findings.
Co-Authors Agus Santosa Devinta, Made Ratih Santi Dharmawan, Made Surya Laksmi, Putu Pradnyasanti MADE RATNA SARASWATI . Tiaraningrum, R.Ratu Kania Yatindra, Ida Ayu Cempaka Dewi