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All Journal Althea Medical Journal Jurnal Kesehatan
Khotijah, Alfreda Amelia
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Medicine & Pharmacology Nursing

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Prognostic Nutritional Index and Systemic Immune-inflammation Index: Possible New Parameters for COVID-19 Severity Suyoso, Suyoso; Oehadian, Amaylia; Khotijah, Alfreda Amelia; Marthoenis, Marthoenis
Althea Medical Journal Vol 10, No 3 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n3.3061

Abstract

Background: The prognostic nutritional index (PNI) parameter has been widely used in estimating the severity of COVID-19. In contrast, investigating the role of the systemic immune-inflammation index (SII) in determining the COVID-19 severity is prospective. This study aimed to investigate the potential of PNI and SII parameters to distinguish the severity of symptoms of COVID-19.Methods: A retrospective observational study was conducted among 209 hospitalized patients with COVID-19. Data were collected from August 2021 to February 2022 in Indonesia’s general COVID-19 referral hospital. Demographic and laboratory data, including PNI and SII, were analyzed and compared between the severe and non-severe symptoms of COVID-19 patients. The statistical analysis of the receiver operating characteristic curve (ROC) and area under curve (AUC) was conducted to predict the potential of these parameters in distinguishing the COVID-19 severity. Results: More than half of this study’s patients (54.55%) were non-severe COVID-19. The SII values in patients with severe symptoms were significantly higher than in those with non-severe symptoms (2,445.24 vs. 1,423.28, p=0.005). In contrast, the PNI value in patients with severe COVID-19 symptoms was significantly lower than those with non-severe symptoms (38.04 vs. 33.93, p<0.001). The area under the curve (AUC) value of PNI was 0.694, meanwhile the SII was 0.635. The optimum cut-off for the PNI was <35.407, whereas the SII was >2,212.787. PNI and SII were the potential new diagnostic parameters for COVID-19 severity.Conclusion: PNI and SII parameters can potentially distinguish the severity of symptoms of COVID-19.
Uncovering the reasons behind irregular visits by patients with type 2 diabetes mellitus Kuntari, Titik; Khotijah, Alfreda Amelia; Basya, Hana Nuraisa; Cakranegara, Rama; Ariant, Zinedine Yusuf; Handayani, Nina Tiwi
Jurnal Kesehatan - STIKes Prima Nusantara Vol 15 No 2 (2024): Jurnal Kesehatan
Publisher : LPPM Universitas Prima Nusantara Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35730/jk.v15i2.1095

Abstract

Background: Type 2 diabetes mellitus (DM) is a non-communicable disease with an increasing incidence. DM is associated with deaths caused by several complications. One of the efforts to manage DM is to control blood glucose by maintaining regular check-ups and treatment compliance. Unfortunately, many people with DM still need to visit health facilities regularly.Purpose: This study aimed to explain the factors associated with the irregularity of type 2 DM patients having check-ups at the public health center (puskesmas).Methods: This cross-sectional study used the medical record data from Grabag II Public Health Center. The subjects were 135 outpatients with type 2 DM and complete medical records.Results: The results showed that visit irregularity was significantly associated with sex (OR = 3.8; 95% CI = 1.12-12.79), distance from home (OR = 0.2; 95% CI =  0.06-0.52), and duration of diagnosis (OR = 0.3; 95% CI=  0.12-0.85), but not with age, insurance, comorbidities, and types of therapy.Conclusion: Factors associated with type 2 diabetes mellitus patients' irregular visits to Puskesmas are sex, distance from home, and duration of diagnosis. Educational interventions at all levels of society should be carried out to increase knowledge about DM and the importance of regular check-ups and medication
Co-Authors Amaylia Oehadian Ariant, Zinedine Yusuf Basya, Hana Nuraisa Cakranegara, Rama Handayani, Nina Tiwi M. Marthoenis Suyoso Suyoso Titik Kuntari