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All Journal Jurnal Kefarmasian AKFARINDO Jurnal Pengabdian Masyarakat Nian Tana
Ibnu Nugroho Saputra
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Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Social Sciences

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FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN SERUM GEL ANTIJERAWAT EKSTRAK ETANOL DAUN KEMANGI (Ocimum basilicum L.)TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 DENGAN VARIASI KONSENTRASI Hydroxyethyl Cellulose (HEC) Ibnu Nugroho Saputra; Opstaria Saptarini; Fitri Kurniasari
Jurnal Kefarmasian Akfarindo Vol 8 No 2 (2023)
Publisher : Akademi Farmasi Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37089/jofar.v8i2.206

Abstract

Daun kemangi mempunyai kandungan senyawa flavonoid yang berfungsi sebagai zat antibakteri mampu menghambat penyumbatan bahan keratin pada lapisan pilosebaseus yang dipicu oleh bakteri yaitu Staphylococcus aureus 25923. Penelitian ini bertujuan untuk memformulasikan ekstrak etanol daun kemangi menjadi sediaan serum gel antijerawat dengan memvariasikan konsentrasi Hydroxyethyl Cellulose (HEC) 0,5%, 0,75%, 1% dan menguji mutu fisik serta aktivitas antibakteri terhadap Staphylococcus aureus 25923. Penelitian dilakukan dengan mengekstraksi daun kemangi menggunakan metode maserasi. Uji evaluasi fisik yang meliputi uji organoleptis, pH, viskositas, homogenitas, stabilitas serta uji aktivitas antibakteri pada sediaan serum gel antijerawat dengan variasi konsentrasi Hydroxyethyl Cellulose (HEC), F1 (0,5%), F2 (0,75%), F3 (1%). Metode difusi yang meliputi penyiapan sempel, pembuatan suspensi biakan, pembuatan media lempeng agar, identifikasi bakteri dan pengujian secara difusi. Hasil penelitian menunjukkan bahwa formula dengan variasi konsentrasi Hydroxyethyl Cellulose (HEC), F1 (0,5%), F2 (0,75%), F3 (1%) memiliki aktivitas antibakteri namun pada formula 2 memiliki mutu fisik paling baik dan memiliki diameter zona hambat sebesar 13,00 mm sedangkan pada formula 1 memiliki zona hambat 14,93 mm dan formula 3 memiliki zona hambat sebesar 10,97 mm.
Optimalisasi Pengetahuan Masyarakat Tentang Penggunaan Obat Harian Secara Aman di Desa Candirejo Ungaran Barat Dea Ayu Vidina; Ibnu Nugroho Saputra; Dimas Adam Asrori; Sikni Retno Karminingtyas
JPMNT JURNAL PENGABDIAN MASYARAKAT NIAN TANA Vol. 4 No. 3 (2026): Juli: Jurnal Pengabdian Masyarakat Nian Tana
Publisher : Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59603/jpmnt.v4i3.1386

Abstract

Irrational drug use remains a common health problem in the community, including the use of medications without following dosage instructions, discontinuation of treatment before completion, the use of antibiotics without prescriptions, and improper drug storage. These problems were also identified among residents of Candirejo Village, West Ungaran District, who still have limited knowledge regarding the safe use of daily medications. This community service activity aimed to improve public knowledge and awareness regarding rational and safe medication use. The implementation methods included program socialization, health education sessions, distribution of educational media in the form of leaflets and posters, and evaluation through question-and-answer sessions and simple quizzes. Educational materials covered how to read medication labels, proper dosage and duration of use, differences between over-the-counter drugs and prescription drugs, risks of antibiotic misuse, and proper medication storage methods. The results of the activity showed an increase in community understanding regarding medication use instructions, the importance of reading labels, the dangers of using antibiotics without prescriptions, and correct drug storage practices. Participants also demonstrated high enthusiasm and active participation during the activities. This program is expected to improve community health literacy and encourage more appropriate, safe, and responsible medication use behavior in daily life.
Co-Authors Dea Ayu Vidina Dimas Adam Asrori Kurniasari, Fitri Opstaria saptarini Sikni Retno Karminingtyas