Ainun Qolbi Wasdili, Fini
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GAMBARAN AKTIVITAS ENZYME ALANINE TRANSAMINASE (ALT) PADA PENGKONSUMSI MINUMAN BERALKOHOL Ainun Qolbi Wasdili, Fini; Aslamiyah, Suaibatul; Romlah, Sitti
JURNAL KESEHATAN KARTIKA Vol. 18 No. 2 (2023): Jurnal Kesehatan Kartika
Publisher : Faculty of Health Science and Technology, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkkes.v18i2.258

Abstract

Alcohol consumption is the third largest risk factor in the world as a cause of disease and disability. There are various types of diseases caused by alcohol consumption, one of which is impaired liver function. Liver function disorders can be indicated by an increase in enzyme activity, one of which is the ALT enzyme. The purpose of this study was to describe the activity of the ALT enzyme in alcoholic beverage consumers. Examination of blood samples has been carried out on alcoholic drink consumers in the "X" community. The type of research conducted is a descriptive study and the method used in the ALT examination is enzimatyc kinetics IFCC. Process of written questionnaire, Informed Consent, as well as examination in the Laboratory. Examination of ALT enzyme activity was carried out at the FITKES UNJANI Laboratory using the Mindray BA-88A tool. This study used 30 samples from alcoholic drink consumers in the "X" community, the results obtained from the examination of ALT enzyme activity in alcoholic beverage consumers were then carried out data management. The results of the examination of 30 samples of alcoholic drinkers whose blood samples were taken 1 day after consuming alcoholic beverages showed abnormal ALT activity examination results in 2 people (7%) and normal results in 28 people (93%)
PERBANDINGAN KADAR UREUM PASIEN GAGAL GINJAL KRONIK YANG MENJALANI TERAPI HEMODIALISA DI RS X TAHUN 2022 PQNAW Kusuma, Ajeng; Ainun Qolbi Wasdili, Fini; Mahargyani, Wikan
JURNAL KESEHATAN KARTIKA Vol. 19 No. 3 (2024): Jurnal Kesehatan Kartika
Publisher : Faculty of Health Science and Technology, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkkes.v19i3.320

Abstract

Background: Chronic renal failure is a condition of decreased kidney function, where the kidneys cannot function to remove metabolic waste in the body that accumulates in the blood. In the end stage of chronic renal failure, hemodialysis therapy is needed to remove the rest of the body's metabolism that accumulates in the blood and reduce the risk of death. The effectiveness of hemodialysis can be seen from the decrease in serum ureum levels in patients with chronic renal failure after hemodialysis therapy. Objective: to determine the description of serum ureum levels in pre and post hemodialysis chronic renal failure patients at X Hospital in 2022 and to get an overview of the effect of hemodialysis on ureum levels. Method: Descriptive Analytic with Cross sectional design. Data collection was done by using a questionnaire. Furthermore, the data were analyzed using the paired sample t-test statistical test. Results: The results obtained p value = 0.000 (α ≤ 0.05) means that there is a difference in ureum levels of chronic renal failure patients before and after undergoing hemodialysis. Conclusion: There was a decrease in serum ureum levels of chronic renal failure patients after hemodialysis therapy, but not all returned to normal values.