Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Puspitasari, Indah Wahyu
Unknown Affiliation
Immunology & microbiology Neuroscience

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Protective effect of corncob extract cream on guinea pig (Cavia porcellus sp) skin pigmentation exposed to ultraviolet B (UVB) rays Harlisa, Pasid; Puspitasari, Indah Wahyu; Yuliyanti, Suryani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 55, No 3 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005503202302

Abstract

Ultraviolet B (UVB) rays exposure causes skin inflammation and pigmentation lead to decrease skin lightness. Corncobs (Zea mays) contain flavonoids which can act as antioxidant to prevent free radicals and protect the skin pigmentation. This study aimed to evaluate the protective effect of corncob extract cream on skin pigmentation exposed to UVB rays. This pre-posttest control group study was applied to 25 guinea pigs (Cavia porcellus sp) randomly divided into five groups. Corncob extract cream was given every day 20 min before and 4 h after UVB exposure. The UVB exposure total dose was 780 mJ/cm2. Mexameter examination was carried out on the 1st day and 28th day after treatment. There were significantly differences in the lightness level and the mean melanin index (MI) difference of guinea pigs before and after intervention on various groups (p<0.05). No significantly different of the MI between pre- and post-treatment was observed on normal control group (0.22) and negative control group (-1.06) (p>0.05). However, significantly different of the MI was observed on positive control group (-4.01), corncob 40% group (-2.72), and corncob 30% group (-2.03) (p<0.05). In conclusion, corncob extract cream can inhibit the skin pigmentation due UVB rays exposure.
Co-Authors Pasid Harlisa Suryani Yuliyanti, Suryani