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All Journal Jurnal Kedokteran Universitas Palangka Raya Journal of Health and Nutrition Research
Ardiputra, Muh. Akbar
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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PERBANDINGAN EKSTRAKSI AKAR KUCING (ACALYPHA INDICA L.) DENGAN EKSTRAK ETANOL 96% DAN EKSTRAK AKUADES TERHADAP PERTUMBUHAN EPEC DAN CANDIDA ALBICANS M. Guli, Musjaya; Zahra, Yuyun Jannatul; Ardiputra, Muh. Akbar; Toemon, Agnes Immanuela
Jurnal Kedokteran Universitas Palangka Raya Vol 11 No 2 (2023): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v11i2.11038

Abstract

The root of the cat (Acalypha indica L.) was used as the object of research and extraction was carried out to determine the antimicrobial activity of 96% ethanol extract and distilled water against EPEC (Enterophatogenic Escherichia coli) bacteria and the fungus Candida albicans. The method used for plant sampling is purposive sampling method. Extraction of active compounds using maceration method. The antimicrobial potency test used the agar-diffusion method using two types of microbial pathogens, namely the bacteria EPEC and the fungus Candida albicans. Each paper disk was given 50 µL of bacterial isolate, incubated at 37 0C for 24 hours and continued for 48 hours. The observed parameter is the clear zone formed around the paper disk. The results showed that cat root (A. indica L.) contains compounds that can inhibit the growth of EPEC bacteria and the fungus C. albicans. A good solvent to extract the active compounds contained in the cat root plant (A. indica L.) is distilled water. Treatment with aquadest extract with a concentration of 100% had the widest inhibition zone among other treatments, namely 6.8 mm against the growth of EPEC bacteria and ethanol extract with a concentration of 100% which was 3.8 mm against the growth of the fungus Candida albicans.
Skrining Fitokimia Tumbuhan Potensi Obat Kanker Kolorektal Begonia Medicinalis Ardi & D.C. Thomas Ardiputra, Muh. Akbar; Musjaya M. Guli; Andi Saifah; Santi; Bambang Sardi; Wafiq Nurfadilah; Mohammad Rivaldi Putra Pratama; Afifah Islamia
Jurnal Kedokteran Universitas Palangka Raya Vol 12 No 2 (2024): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v12i2.13207

Abstract

Cancer is a condition in which cells or tissues undergo abnormal progressive growth. Colorectal cancer is cancer that occurs in the colon to rectum organs of humans. Alternative therapy for colorectal cancer treatment is the use of herbs such as Begonia medicinalis Ardi & D.C. Thomas. This study aimed to screen the bioactive compounds in the Begonia medicinalis Ardi & D.C. Thomas. extract and its potential as a colorectal cancer drug. This research consists of two stages, namely the extraction stage using the maceration method and the screening stage. The results showed that the extract of Begonia medicinalis Ardi & D.C. Thomas. positively contains flavonoids, alkaloids, and saponins. These bioactive compounds have potential activity as preventive and curative agents for colorectal cancer through several mechanisms, including suppressing oxidative stress, inhibiting CDK activity, suppressing intestinal inflammation, and increasing floranormal diversity and probiotic barrier activity in the intestine.
Faktor-Faktor yang Mempengaruhi Peyakit Diabetes Melitus di Kota Palu Musjaya M.; Ayu Dia Agustina; Nur Annisa Safirah; Ardiputra, Muh. Akbar; Sardi, Bambang; Saifah, Andi; Putra, Suwarty Nursahara Usman
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.19586

Abstract

Diabetes mellitus is a metabolic disorder caused by insufficient production of the hormone insulin by the pancreas. This disease can be said to be a chronic disease because it can occur over a long period . This research is about the factors that influence Diabetes Melitus disease in Palu City. This study aims to determine the description of patient visits suffering from Diabetes Melitus at the Central Sulawesi Provincial Laboratory. The sampling technique uses the purpose sampling method, namely purposeful sampling or sampling carried out with subjects based on criteria set by the researcher. The results of this study analyze the factors that influence Diabetes Melitus disease in Palu City. The research result obtained were that there were more women with 288 people and 132 men. Meanwhile, in 2024 from January to march, there will be 90 women and 44 men, the number of patients suffering from diabetes melitus. Namely those aged 46-55 ini 2023 there will be 240 people and ini 2024 there will be 143 people with diabetes melitus agen 40-59 person. The gender factor is that there are more female sufferers of diabetes mellitus compared to male sufferers    
Ambient Air Pollution Exposure and Social Health Outcomes in Communities Near the Kawatuna Landfill, Palu, Indonesia Saifah, Andi; Ardiputra, Muh. Akbar; Miswan, Miswan; Safirah, Nur Annisa; Arifuddin, Adhar; Guli, Musjaya; Parmin, Parmin
Journal of Health and Nutrition Research Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i2.540

Abstract

Communities living near landfill sites are often exposed to high levels of ambient air pollution, which may impact their physical and psychosocial health. This study aims to explore the relationship between ambient air pollution exposure, particularly carbon monoxide (CO) and nitrogen dioxide (NO₂), and the social health outcomes of communities residing near the Kawatuna Landfill in Palu, Indonesia. A cross-sectional study involving 143 respondents was conducted using structured interviews and environmental exposure assessments. Correlation analyses, Mann-Whitney U tests, and regression models were applied to examine the relationships between air pollution exposure and respiratory disorders, smoking behavior, stress levels, and social interaction. The findings revealed a significant positive correlation between CO and NO₂ exposure and stress levels (r=0.217, p = 0.022), although the relationship was weak. No significant associations were found between air pollution exposure and smoking behavior, social interaction, or respiratory disorders in multivariate analyses. The Mann-Whitney U test indicated that individuals with respiratory disorders were exposed to higher levels of CO and NO₂ (p = 0.038). Ambient air pollution exposure in this community is more closely related to psychosocial stress than to physical health behaviors or social interaction. Community-based health interventions should consider the cultural context and perceived environmental risks to effectively promote health in such vulnerable populations.
Co-Authors Adhar Arifuddin Afifah Islamia Andi Saifah Ayu Dia Agustina Bambang Sardi Guli, Musjaya Miswan Miswan Mohammad Rivaldi Putra Pratama Musjaya M. Musjaya M. Guli Nur Annisa Safirah Parmin - Putra, Suwarty Nursahara Usman Safirah, Nur Annisa Santi Toemon, Agnes Immanuela Wafiq Nurfadilah Zahra, Yuyun Jannatul