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All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Pengabdian Masyarakat Tjut Nyak Dhien
Firdaus, Tya Novita
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Religion Chemistry Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Penyuluhan Penggunaan Obat Antibiotika Yang Tepat Pada Ibu PKK Di Desa Sunggal Tambunan, Ika Julianti; Febriani, Yessi; Nadia, Syarifah; Margatha, Linda; Sihotang, Supran Hidayat; Putri, Nurul Maulida; Pratiwi, Nur Hanifa; Firdaus, Tya Novita
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 3 No 2 (2024): Edisi Juli 2024 - Desember 2024
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v3i2.1283

Abstract

Pengobatan sendiri dengan antibiotik sering dipengaruhi oleh faktor kesehatan sosio-kultural dan terkadang terkait dengan penyerahan antibiotik tanpa resep serta praktik peresepan yang kurang baik. Masyarakat memiliki peran penting dalam mencegah dan mengendalikan penyebaran resistensi antibiotik. Tingginya penyalahgunaan antibiotik di masyarakat disebabkan oleh rendahnya pengetahuan tentang penggunaan yang tepat. Tujuan dari pengabdian ini adalah menyebarkan pemahaman kepada masyarakat mengenai penggunaan antibiotik yang benar untuk mencegah terjadinya resistensi antibiotik. Metode pengabdian ini melibatkan pendekatan deskriptif dengan menggunakan kuisioner pre-test dan post-test untuk menganalisis pemahaman masyarakat sebelum dan setelah pemaparan materi. Pengabdian ini, dihadiri 25 partisipan yang terdiri dari ketua dan anggota PKK Desa Sunggal, Dosen dan mahasiswa Fakultas Farmasi Universitas Tjut Nyak Dhien. Harapannya pengabdian ini dapat memberikan pengetahuan tentang cara yang tepat dalam menggunakan antibiotik untuk menghindari resistensi yang dapat berdampak pada Kesehatan dan perekonomian.
Phytochemical Screening and Anti-hyperglycemic Effect Test of Ethanol Extract of Waru Leaf (Hibiscus tiliaceus) on Glucose-loaded Mice Sofia, Vivi; Firdaus, Tya Novita; Saputri, Muharni
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 3 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i32024.345-355

Abstract

Background: The treatment of diabetes mellitus relies on synthetic drugs with various side effects. Therefore, it is necessary to explore alternative treatments with herbal therapies, such as Hibiscus tiliaceus leaves. Objectives: The aim of this study was to determine the anti-hyperglycemic effect of an ethanol extract from Hibiscus tiliaceus leaves in glucose-loaded mice. Methods: The initial stage of dried leaf characterization was to ensure the identity, quality, purity, and safety to be used, and then extracted using the maceration method with 70% ethanol solvent. The next step was phytochemical screening to identify secondary metabolite content. The anti-hyperglycemic effect was evaluated using the oral glucose tolerance test (OGTT) on 25 male mice divided into five treatment groups. The negative control group was given Na CMC 0.5% w/v Na CMC, and the positive control group was administered glibenclamide. The ethanol extract of Hibiscus tiliaceus leaves was administered at doses of 200, 400, and 800 mg/kg. Approximately 200 µL of blood was collected and analyzed for glucose levels. The data were statistically analyzed using one-way analysis of variance (ANOVA) with SPSS ver. 25 program. Results: Hibiscus tiliaceus leaves contain alkaloids, flavonoids, saponins, and tannins. The highest decrease in blood glucose levels was observed in the ethanol extract group at a dose of 400 mg/kg BW, with a decrease of 78.52%, followed by a dose of 200 mg/kg BW of 76.63%, a dose group of 800 mg/kg BW of 73.48%, and a positive control group (glibenclamide) of 34.68%, which was significantly different from the negative control group (Na CMC 0.5%) (p < 0.05). Conclusion: The ethanol extract of H. tiliaceus has anti-hyperglycemic effects.
Co-Authors Febriani, Yessi Margatha, Linda Nadia, Syarifah Pratiwi, Nur Hanifa Putri, Nurul Maulida Saputri, Muharni Sihotang, Supran Hidayat Tambunan, Ika Julianti Vivi Sofia