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All Journal Jurnal Teknosains IJOEP : International Journal of Ecophysiology Journal of Agri-Food Science and Technology (JAFoST)
Wati, Dini Prastyo
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Industrial & Manufacturing Engineering Mechanical Engineering

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Combination effectiveness of glucomannan and moringa oleifera leaf extract on lipid profil of hypercholesterolemia rats Wati, Dini Prastyo; Setyaningsih, Endang
Jurnal Teknosains Vol 13, No 1 (2023): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.82693

Abstract

cholesterol levels in the blood. This study aims to determine the effectiveness of the combination of glucomannan (Amorphophallus muelleri Blume) and Moringa oleifera leaf extract on the lipid profile of hypercholesterolemic Wistar rats. This research design used True experimental with a pretest-posttest control group design. The animal used in this study was 24 male Wistar rats (Rattus norvegicus) aged 8 weeks divided into 2 control groups and 6 treatment groups of glucomannan and Moringa oleifera leaf extract. The results of this study showed that there were significant changes in TC, TG, LDL-C, and HDL-C levels (p<0.05). It can be concluded that the combination of glucomannan (Amorphophallus muelleri Blume) and Moringa oleifera leaf extract can change the lipid profile effectively in the P5 (80mg/kgBW GAmB: 120mg/kgBW MoEL) and P4 (120mg/kgBW GAmB:80mg/kgBW MoEL ) as the most influential group in reducing TG, TC, LDL-C levels and increasing HDL-C levels.
Moringa oleifera Leaf Extract and (Amorphophallus muelleri Blume.) Glucomannan Effects on Obese White Rat Feed Intake and Body Weight Wati, Dini Prastyo; Endang Setyaningsih
International Journal of Ecophysiology Vol. 6 No. 1 (2024): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v6i1.15990

Abstract

Obesity significantly raises the rates of illness and death in humans due to its association with several health conditions such as cardiovascular disease, hypertension, hypercholesterolemia, type 2 diabetes mellitus, osteoporosis, depression, breast cancer, and colon cancer. This study aims to determine the effect of Moringa oleifera leaf extract and glucomannan (Amorphophallus muelleri Blume.) on feed intake and body weight of obese white rats. This study used an experimental method with a pretest-posttest-only control grub design using 24 white male rats of the Wistar strain aged 8 weeks which were divided into 2 control groups, namely positive(K1) and negative(K2) and six treatment groups with extract doses Moringa oleifera leaves and glucomannan (Amorphophallus muelleri Blume.) 100mg/kgBW:100mg/kgBW(K3), 80mg/kgBW:120mg/kgBW(K4), 120mg/kgBW: 80mg/kgBW(K5), 50mg/kgBW:50mg/kgBW(K6), 40mg/kgBW:60mg/kgBW(K7), and 60mg/kgBW:40mg/kgBW(K8). Data analysis on body weight and feed intake used the SPSS ANOVA test and paired T-test. The results of the paired T-test (p<0.05) showed that Moringa oleifera leaf extract and glucomannan (Amorphophallus muelleri Blume.) significantly reduced body weight and feed intake. In conclusion, administration of Moringa oleifera leaf extract and glucomannan (Amorphophallus muelleri Blume.) in group K4 (80 mg/kgBW Moringa oleifera leaf extract: 120 mg/kgBW glucomannan Amorphophallus muelleri Blume) can reduce feed intake (4.29 g) and body weight (36.67 g) effectively.
The Substitution of Purslane Weed (Portulaca oleracea L.) Flour and Glucomannan Powder on Organoleptic and Proximate Test of Instant Noodles Wati, Dini Prastyo; Fajrina, Meinira Dinar; Putra, Sahasika Sean; Suryani, Titik
Journal of Agri-Food Science and Technology Vol. 5 No. 1 (2024): April
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jafost.v5i1.9380

Abstract

Instant noodles are a food product that the public highly favors because of their diverse taste, easy presentation, and economical price. Instant noodles cannot be considered whole food because they do not meet the needs of balanced nutrition for the body. Purslane flour (Portulaca oleracea L.) contains macronutrients and micronutrients in the form of carbohydrates, protein, dopamine, potassium salts, tannins, saponins, vitamin A (β-carotene), Vitamin B, Vitamin C, nicotinic acid and natural antioxidants related to fatty acids omega 3 by 44.29%. This study contributed to compare the effectiveness of the substitution of Purslane flour and glucomannan powder on organoleptic test instant noodles. This study was an experiment with a completely randomized design of two-factorial with six treatments including the formulation of purslane flour 25%, 30%, and 35%, while glucomannan formulation of 5%, 10%, 15% with two temperature treatments, 50 °C, and 60 °C. We conducted an organoleptic test with statistical analysis t-test and descriptive. The substitution of purslane flour and glucomannan in instant noodles gave the best organoleptic characteristics in the K2S2 treatment (the formulation of 60% wheat flour, 30% purslane flour, and 10% glucomannan at a drying temperature of 60 °C) with proximate analysis content of 12.26% moisture, 5.53% ash, 5.13% fat, 13.91% protein, and 63.14% carbohydrates.
Co-Authors Endang Setyaningsih Fajrina, Meinira Dinar Putra, Sahasika Sean Titik Suryani