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All Journal Jurnal Kesehatan Prima JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH
Meliana, Ahila
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Health Professions Medicine & Pharmacology Nursing Public Health

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Effect of Solo Garlic Extract (Allium Sativum) on Malondialdehyde (MDA) in Rats (Rattus Norvegicus) Exposed to Cigarette Smoke Kinasih, Dewangga Sakti Satria; Meliana, Ahila; Safitri, Indri
Jurnal Kesehatan Prima Vol 18, No 1 (2024): FEBRUARY
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v18i1.1497

Abstract

Cigarette smoke is one of the oxidant sources which cause stress oxidative. Cigarettes contain more than 4500 gases and chemicals that have negative effect on human body. Stress oxidative is marked by various parameters, one of which is malondialdehyde (MDA). As natural plant, solo garlic has a potential as antioxidant because contain a lot of active compounds. This study determines the effect of solo garlic on MDA level of Rattus norvagicus which exposed to cigarette smoke. This study is experimental animal study which use randomized posttest only control group design. Twenty-five rats were included and divided into five groups, such as negative control, positive control, and the treatment groups. Solo garlic administrated at doses of doses of 2.5, 5, and 10 (mg/200gBW/day) respectively. The statistical result showed that solo garlic extract can reduce the MDA level of treatment groups (p=0.000). This study concluded that solo garlic extract can reduce the MDA levels of rats to cigarette smoke. The significant effect was obtained at a dose of 10 mg/200gBW/day.
Attitude and Behavior Towards Covid-19 Control Among High School Students in Surabaya and Sidoarjo, Indonesia Muhammad Nuh Ihsan; Meliana, Ahila; Hasanatuludhhiyah, Nurina; Visuddho , Visuddho; Abdul Khairul Rizki Purba; Annete D'Arqom
Journal of Community Medicine and Public Health Research Vol. 4 No. 1 (2023): Journal Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jcmphr.v4i1.41954

Abstract

Morbidity and mortality due to Covid-19 tend to be milder in adolescents. Nevertheless, their perception, attitude, and behavior towards Covid-19 deserve attention since they would also contribute to the success of Covid-19 control. Therefore, the aim of this study was to examine the perceived severity, susceptibility, attitudes, and behavior toward Covid-19 among high school students. This was a cross-sectional study conducted in five schools in Surabaya and Sidoarjo. Questionnaires were given online to teachers who then forwarded them to high school students. Data were taken from July to October 2021. Attitude and behavior were examined using the scoring previously tested. The data were then analyzed using Mann-Whitney U and Spearman's correlation tests. The significance level was set at p<0.05. More than 50% of students had good preventive behavior, the most frequent one was wearing masks (87.3%), followed by washing hands (73%). The behavior was correlated with their attitude (r= 0.285, p=0.000). Fifty-three percent of the respondents felt they would experience mild symptoms if they were infected with Covid-19. Most students perceived that they were susceptible to getting infected with Covid-19. Significant results were obtained using the Mann-Whitney test on gender toward attitudes and behavior (p<0.05). There were significant correlations between the mother's educational level (r=0.164, p=0.001) and the father's educational levels (r=0.120, p=0.013) with attitude toward Covid-19 control policies. Female students in Surabaya and Sidoarjo have better behavior in dealing with the Covid-19 pandemic. Parents' educational level plays a role in influencing the student's attitude toward Covid-19 control.
Effect of Solo Garlic Extract (Allium Sativum) on Malondialdehyde (MDA) in Rats (Rattus Norvegicus) Exposed to Cigarette Smoke Kinasih, Dewangga Sakti Satria; Meliana, Ahila; Safitri, Indri
Jurnal Kesehatan Prima Vol. 18 No. 1 (2024): FEBRUARY
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v18i1.1497

Abstract

Cigarette smoke is one of the oxidant sources which cause stress oxidative. Cigarettes contain more than 4500 gases and chemicals that have negative effect on human body. Stress oxidative is marked by various parameters, one of which is malondialdehyde (MDA). As natural plant, solo garlic has a potential as antioxidant because contain a lot of active compounds. This study determines the effect of solo garlic on MDA level of Rattus norvagicus which exposed to cigarette smoke. This study is experimental animal study which use randomized posttest only control group design. Twenty-five rats were included and divided into five groups, such as negative control, positive control, and the treatment groups. Solo garlic administrated at doses of doses of 2.5, 5, and 10 (mg/200gBW/day) respectively. The statistical result showed that solo garlic extract can reduce the MDA level of treatment groups (p=0.000). This study concluded that solo garlic extract can reduce the MDA levels of rats to cigarette smoke. The significant effect was obtained at a dose of 10 mg/200gBW/day.
Co-Authors Abdul Khairul Rizki Purba Mustofa Indwiani Astuti Annete D'Arqom Indri Safitri, Indri Kinasih, Dewangga Sakti Satria Muhammad Nuh Ihsan Nurina Hasanatuludhhiyah Visuddho , Visuddho