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All Journal JOURNAL LA MEDIHEALTICO AMMA : Jurnal Pengabdian Masyarakat
Nurrifdah, Nadilla
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Humanities Chemistry Health Professions Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary

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Aloin Extract on Histopathological Features of Osteogenesis in Fractures of Rattus Norvegicus Wistar Strains Abdullah, Dessy; Nurrifdah, Nadilla; Febrianto, Budi Yulhasfi; Vani, Ade Teti; Dewi, Nadia Purnama
Journal La Medihealtico Vol. 5 No. 1 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i1.1049

Abstract

The process of bone repair after trauma or fracture will involve cells, signalling molecules, and processes that have been active during the remodelling process. The new study found that Aloin can promote the expression of osteogenic differentiation regulators, such as Bmp-1 (Bone morphogenetic protein 1) and Runx1 (Runt-related transcription factor 1) in MC3T3–E1 cells, where Runx1 is a transcription factor in osteogenic differentiation—knowing and analyzing aloin extract on the histopathological picture of osteogenesis in Wistar strain rattus norvegicus fractures. This type of research is a laboratory experimental test with a post-test-only control group design. The population number will be divided into four groups, namely positive control group (+), negative control (-), treatment group 1, and treatment group 1, with 14 samples using the Purposive Sampling technique. Univariate data analysis is presented as mean and standard deviation and one-way ANOVA statistical test. Data processing using computerized IBM version 15.0 of the SPSS program. Histopathological picture of osteogenesis in fractures of male rats (Rattus norvegicus) based on osteoblast values at least at K(-), which is 30.64, and K(+), which is 31.90. In the P1 group, the highest average osteoblast value was 39.58, and P1's was 38.14. The osteoclast value is obtained at least at K(-) and 8, and K(+) is 19.01. In the P1 group, the highest average osteoclast value was 16.73, and P1 was 11.70. Aloin extract did not affect the histopathological picture of osteogenesis in fractures of male rats (Rattus norvegicus) with a sig of >0.05.
Penyuluhan Perilaku Hidup Bersih Dan Sehat Di SDN 16 Air Tawar Padang Utara Birman, Yuliza; Rosmaini; Wahyuda Ismail, Fikri; Peratami Putri, Shyntia; Nurrifdah, Nadilla; Wanandri, Puja; Azzahra, Latifah; Saputra, Rezy; Widya Kartika, Dwita
AMMA : Jurnal Pengabdian Masyarakat Vol. 2 No. 4 (2023): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Clean and healthy life behavior, often abbreviated as PHBS, is all behavior as a form of embodiment of a healthy life orientation in individual, family and community culture, which aims to improve, maintain and protect one's health physically, mentally, spiritually and socially. One of the most important PHBS is PHBS in schools. PHBS in schools is an activity to empower students, teachers and the school community to want to adopt a healthy lifestyle to create healthy schools. The benefits of PHBS in schools are able to create a clean and healthy environment, improve the teaching and learning process and students, teachers and the school community become healthy. implementation of PHBS in schools includes washing hands with soap, consuming healthy snacks, using clean and healthy latrines, exercising regularly, eradicating mosquito larvae, not smoking in the school environment, disposing of trash in its place, and, doing community service with school residents to creating a healthy environment. Health promotion regarding PHBS was carried out at SDN 16 Air Tawar, North Padang District, Padang City on Saturday, December 3, 2022 with a total of 46 participants consisting of grade 3 and 4 students.
Co-Authors Abdullah, Dessy Azzahra, Latifah Birman, Yuliza Dewi, Nadia Purnama Febrianto, Budi Yulhasfi Peratami Putri, Shyntia Rosmaini Saputra, Rezy Vani, Ade Teti Wahyuda Ismail, Fikri Wanandri, Puja Widya Kartika, Dwita