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All Journal Pancasakti Journal Of Public Health Science And Research Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Tambunan, Adrian Nurrachman
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Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Relationship between LDH Levels with COVID-19 Degree of Severity Tambunan, Adrian Nurrachman; Ganie, Ratna Akbari; Tarigan, Amira Permatasari
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 4 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i4.14414

Abstract

Background: LDH has proved to be a significant predictor for prognosis and follow-up in COVID-19 patients. Several studies report elevated LDH in hospitalized COVID-19 patients to be associated with a higher risk of death. Increased LDH levels can result from any tissue damage due to SARS-CoV-2 infection. The study aims to describe the relationship between LDH levels with COVID-19 19 degree of severity. Methods: This study is a cross-sectional study of 55 patients who confirmed positive by RT-PCR SARS-CoV-2 at H. Adam Malik General Hospital Medan (November 2021 – Maret 2022). Examination of the LDH level was carried out by the Chemiluminescent Immunoassays method (Abbott Architect). COVID-19 degree of severity was assessed based on the diagnostic criteria for COVID-19 cases in Indonesia. Results: Among the 55 COVID-19 patients in this study, the average age found was 45.73, with men 54.5%. Moderate, severe, and critical patients were found in 63.6%; 29.1%; and 7.3% respectively. The mean LDH level at admission was 278 U/L, higher in the severe (333.19 U/L) and critical (465.75 U/L) groups compared to the moderate (231.31 U/L) groups. Increased LDH ≥ 256 U/L proved to be related to COVID-19 degree of severity upon hospital admission (CI 95%; p = 0.001). Conclusions: LDH levels that increased ≥ 256 U/L were significantly related to COVID-19 degree of severity during hospital admission.
The Effect of Botox on Women of Productive Age at Evoluskin Batam Clinic Mangkuanom, Adrian Saleh; Rusip, Gusbakti; Mutia, Maya Sari; Putra, Ananda Rahmat; Tambunan, Adrian Nurrachman
Pancasakti Journal Of Public Health Science And Research Vol 5 No 2 (2025): PJPHSR
Publisher : Fakultas Kesehatan Masyarakat, Universitas Pancasakti, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47650/pjphsr.v5i2.1893

Abstract

Botox (botulinum toxin) is a commonly used aesthetic procedure to reduce facial wrinkles, especially in women of reproductive age. Although its physical benefits have been widely recognized, the effect of Botox on the psychological aspects and quality of life of patients still needs to be studied further. This study aims to analyze the impact of Botox use on the patient's skin condition, self-esteem, self-confidence, and quality of life psychologically, socially, and physically. This quantitative study involved 30 respondents selected by purposive sampling. Data were collected through a questionnaire measuring the frequency of Botox use, dosage, and using the Rosenberg Self-Esteem Scale and WHOQOL-BREF to measure quality of life. Data were analyzed using paired t-test and Pearson correlation at 0.05 level of significance. The results showed a significant reduction in wrinkles and skin problems after Botox treatment (mean from 49% to 34%, p=0.003). There was a significant positive relationship between Botox use and self-esteem (r=0.45, p=0.012), self-confidence (r=0.38, p=0.025), and quality of life (r=0.62, p<0.001). These findings indicate that Botox has a positive effect not only on physical appearance, but also on the psychological aspects and overall quality of life of patients.
Co-Authors Gusbakti Rusip Mangkuanom, Adrian Saleh Mutia, Maya Sari Putra, Ananda Rahmat Ratna Akbari Ganie, Ratna Akbari Tarigan, Amira Permatasari