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All Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Kaban, Sri Melinda
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Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Relationship between Gastroesophageal Reflux Disease (GERD) with Quality of Sleep Ginting, Elianora Bergita; Darmadi; Sofyan, Ferryan; Kaban, Sri Melinda
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 2 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i2.14955

Abstract

Background. Gastroesophageal Reflux Disease (GERD) is a common gastrointestinal disorder caused by reflux of stomach contents into the esophagus, as a result, it causes various symptoms or complications . GERD is a commonly prevalent gastrointestinal disorder in medical students. Based on data from the 2006 US National Health and Wellness survey observing respondents who experienced heartburn at least twice a month, 89% of respondents experiencing nightime GERD symptoms, it showed that the presence of nighttime GERD was associated with decrease quality of sleep. This study aimed to analyze the relationship between GERD and students’ sleep quality in Faculty of Medicine USU 2020-2022. Method. Cross sectional design with total sampling method. Data collection was carried out using an online questionnaire in the form of a google form. The questionnaires used were GERD-Q, FSSG, PSQI, and ISI. The analysis used was univariate and bivariate analysis with Chi-square. Results. This study involved 378 respondents, 114 people (30.2%) with GERD, 67 people (58.8%) with severe of GERD, 286 people (75.7%) had a bad quality of sleep, and 43 people (15%) with moderate and severe of insomnia. The results of statistical analysis showed an association between GERD and quality of sleep. Conclusion. There was a correlation between GERD and quality of sleep of USU Faculty of Medicine students class 2020-2022
The Relationship between SLC22A16 Gene Polymorphism and Hematological Toxicity in Breast Cancer Patients Receiving Doxorubicin-Based Chemotherapy KABAN, SRI MELINDA; Siti Syarifah; Pane, Yunita Sari; Tri Widyawati
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 1 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i1.18520

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ABSTRACT Background Drug transporter polymorphisms are widely associated with the risk of toxicity in many chemotherapy drugs in cancer. This paper aims to assess the relationship of polymorphisms of this transporter, namely SLC22A16, which are associated with side effects of Doxorubicin-based chemotherapy drugs, namely hematological toxicity (anemia, neutropenia, leukopenia and thrombocytopenia) in breast cancer patients. Method This cross-sectional study will be conducted by testing polymorphism using the ARMS PCR method, which will assess the distribution of AA, AG, and GG genotypes. Result  Most patient ages are under 50 years (55%), with overweight BMI (41,7%) and Batak ethnicity (43,3%). There is no relationship between SLC22A16 Gene Polymorphism and Hematological Toxicity in Breast Cancer Patients Receiving Doxorubicin-Based Chemotherapy
Corelation Between Level of Knowledge and Antibiotic Use Behaviour in Kelurahan Sei Putih Timur, Medan KABAN, SRI MELINDA; Kumar, Ajith; Hafaz Zakky Abdillah; Anggrreiny; Siti Syarifah
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 4 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i4.20830

Abstract

Background: Antibiotics are one of the great discoveries in the world of health that have saved many lives since their invention by Sir Henry Flaming in 1928. Not long after its discovery, antibiotic usage faced a new issue, which is antibiotic resistance that caused antibiotic effectivity to decrease and caused millions of deaths ever since. Until now, antibiotics have become a global threat that has to be solved. This research aims to determine the community’s knowledge level about antibiotics, if their use of antibiotics is rational, and if knowledge about antibiotics in the community will affect their usage of antibiotics. Method: A cross-sectional strategy is used in this descriptive-analytical study. The population and sample of this study were the community of Kelurahan Sei Putih Timur 2 Medan that met the criteria of respondents of 120 people.T Results and Discussion: The results obtained were 38 respondent (31.7%) has insufficient level of knowledge about antibiotics, 56 respondent (46.7%) has sufficient knowledge and 26 respondent (21.7%) has good knowledge about antibiotics. The number of respondent who has rational usage of antibiotics was 69 (57.5%) and the other 51 respondent (42.5%) has irrational usage of antibiotics. From analysis, 63 respondent, has sufficient to good knowledge about antibiotics and rational usage of it. Conclusion: Most of the antibiotic use behaviour of the East Sei Putih 2 Community is classified as rational, and has sufficient knowledge about antibiotics
Co-Authors Anggrreiny Darmadi Ferryan Sofyan Ginting, Elianora Bergita Hafaz Zakky Abdillah Kumar, Ajith Pane, Yunita Sari Siti Syarifah Tri Widyawati