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All Journal Agroprimatech Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Vitamin: Jurnal Ilmu Kesehatan Umum
Finna Piska
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Agriculture, Biological Sciences & Forestry Dentistry Environmental Science Health Professions Nursing Public Health Veterinary

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Uji Toksisitas Subkronik Ekstrak Etanol Biji Ketumbar (Coriandrum Sativum L.) Terhadap Fungsi Jantung Dan Paru-Paru Pada Tikus Jantan (Rattus Norvegicu.) Jennie Try Varian Laoli; Nerly Juli Pranita Simanjuntak; Finna Piska
An-Najat Vol. 2 No. 3 (2024): AGUSTUS - An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i3.1530

Abstract

Coriander seed plant (Coriandrum sativum.) Apiaceae family As an alternative medicine to reduce various risk factors for heart disease including LDL cholesterol levels and high blood pressure, characterization and preparation of ethanol extract of coriander seeds (EEBK) using the maceration method was the first step in this research, followed by with subchronic toxicity testing. Subchronic toxicity testing used male rats (Rattus Norvegicu.) each of which was divided into 5 groups, namely control CMC Na 0.5%, EEBK doses of 100, 200, 400 and 500 mg/kg bw. In the subchronic toxicity test, the parameters observed included toxic symptoms, changes in body weight, death, as well as microscopic and macroscopic examination of organs, including hematological examination. This observation lasted for 28 days. Subchronic test data were analyzed using the Statistical Product and Service Solution with two-way ANOVA, followed by the Tukey and Kruskal-Wallis post-hoc test. Findings from the subchronic toxicity study indicated that EEBK did not have a toxic effect, because there was no significant difference in changes relative organ weight, body weight, number of mouse deaths, toxic symptoms, organ macroscopic, and hematological values ​​were compared with the control group (P > 0.05).
Karakteristik Fisik Sabun Organik Berbasis Minyak Jelantah dan Ekstrak Buah Pinang (Areca cathecu L) Dengan Biosurfaktan Buah Lerak (Sapindus rarak DC) Agustina, Nur Ariyani; Finna Piska
Agroprimatech Vol. 7 No. 2 (2023): Agroprimatech
Publisher : Prodi Agroteknologi Fakultas Agro Teknologi Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/agroprimatech.v7i1.4416

Abstract

Used cooking oil waste is very dangerous for the environment if it is not used or processed properly. Used cooking oil can be used as a raw material for used cooking oil mixed with areca nut. Areca nut contains substances that are beneficial for skin health such as tannins, alkaloids, and flavonoids. In improving the quality of this organic soap, biosurfactants from lerak fruit can also be added as a mixture of organic soaps. This research aims to develop an organic soap based on used cooking oil and areca nut extract with lerak fruit biosurfactant to improve skin health and reduce negative environmental impacts. The research method used a 2 factorial completely randomized design with factor 1, namely areca nut extract (P) which consisted of 3 levels: 4 mL, 6 mL, and 8 mL. Factor 2 was lerak fruit extract (L) which consisted of 3 levels, namely 35%, 45%, and 55%. The research results obtained that activated charcoal and zeolite are very effective in absorbing impurities contained in used cooking oil. This can be seen from the clear golden yellow color of the used cooking oil that has been purified. In organoleptic testing, it was found to have a dark red color, a characteristic odor and a thick texture. The results showed that the addition of areca nut extract and lerak fruit extract had a very significant effect on the results of variance where P<0.05 for all test parameters. The best treatment was found in P3L3 where 8 mL of areca nut extract and 55% of lerak fruit extract resulted in a pH of 8.89, foam height of 10.4 cm, foam stability of 97%, water content of 34.97%. The results of all treatments show that they have fulfilled SNI 06-4085-1996 which can be used as organic liquid body soap. Keyword: lerak, organic soap, used cooking oil, areca nut, biosurfactant
Rasionalitas Penggunaan Obat Hiperurisemia dan Gout Artritis di Poli Penyakit dalam RSU Royal Prima Marelan Olivia Happy Novita; Razoki Lubis; Finna Piska
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 3 No. 2 (2025): April : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v3i2.1307

Abstract

The use of drugs for hyperuricemia and gout arthritis is given for conditions that cause higher purine metabolism in the body. This study was conducted at RSU Royal Prima Marelan to determine the pattern of drug use for hyperuricemia and gout arthritis due to inflammation caused by uric acid deposits in the joints. Data collection in this study was carried out retrospectively by collecting medical records of patients with hyperuricemia and gout arthritis. The descriptive method used in this study was a cross-sectional plan. Qualitative descriptive analysis was applied to the data. Tables or narratives were used to present the data in this study. The results showed that 30 patients out of 50 were male and 20 were female. The results of the evaluation of the rationality of drug use for hyperuricemia and gout arthritis showed that patients who were given several versions of drugs with the xanthine oxidase inhibitor group 64% were allopurinol with patients with the most appropriate indications, the right patient, and the right dose of 96%.
Co-Authors Jennie Try Varian Laoli Nerly Juli Pranita Simanjuntak Nur Ariyani Agustina Olivia Happy Novita Razoki Lubis