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All Journal Jurnal Mahasiswa Ilmu Kesehatan Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan Vitamin: Jurnal Ilmu Kesehatan Umum
Razoki Lubis
Unknown Affiliation
Health Professions Nursing Public Health

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Uji Aktivitas Ekstrak Etanol Daun Kersen (Muntingia Calabura) Terhadap Bakteri Staphylococcus Aureus Dari Luka Diabetes Syahratul Hasanah; Meldawati; Razoki Lubis
Jurnal Mahasiswa Ilmu Kesehatan Vol. 2 No. 3 (2024): Juli: Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v2i3.1507

Abstract

Gangrenous wounds are wounds that occur due to diabetes complications caused by nerve damage and poor blood circulation which makes diabetic wounds unable to prevent infection. Infection is caused by the growth of microbes. High levels of sugar in the blood of DM sufferers provide food for microbes to reproduce. One of the bacteria that causes gangrene is Staphylococcus aureus. Plants that can be used as antibacterials are cherry leaves, also known as seri (Muntingia calabura L.), which contain tannins, terpenoids, saponins, flavonoids and polyphenols. This research aims to identify the antibacterial activity of cherry leaf extract against Staphylococcus aureus bacteria from DM wound wipes. This research was carried out in an experimental laboratory by applying the disc diffusion research method. The resistance is measured through the clear zone that extends around the paper disc. Kersen leaf extract was obtained through a maceration process with 96% ethanol solvent to obtain a thick extract of 0.074%. The test concentrations used were 12.5%, 25%, 50% and 75%. Positive control tetracycline 500 mg and negative control DMSO (dimethyl sulfoxide). The results of this research show that Kersen leaf extract inhibits the growth of Staphylococcus aureus bacteria in diabetic wounds. In concentrations of 12.5%, 25%, 50%, and 75%, the average diameter obtained was 2.70 mm, 4.67 mm, 6.30 mm, 7.89 mm. Conclusion: the effect of ethanol extract of cherry leaves on the growth of Staphylococcus aureus bacteria in diabetic wounds is antibacterial.
Rasionalitas Penggunaan Obat Hiperurisemia dan Gout Artritis di Poli Penyakit dalam RSU Royal Prima Marelan Olivia Happy Novita; Razoki Lubis; Finna Piska
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 3 No. 2 (2025): April : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v3i2.1307

Abstract

The use of drugs for hyperuricemia and gout arthritis is given for conditions that cause higher purine metabolism in the body. This study was conducted at RSU Royal Prima Marelan to determine the pattern of drug use for hyperuricemia and gout arthritis due to inflammation caused by uric acid deposits in the joints. Data collection in this study was carried out retrospectively by collecting medical records of patients with hyperuricemia and gout arthritis. The descriptive method used in this study was a cross-sectional plan. Qualitative descriptive analysis was applied to the data. Tables or narratives were used to present the data in this study. The results showed that 30 patients out of 50 were male and 20 were female. The results of the evaluation of the rationality of drug use for hyperuricemia and gout arthritis showed that patients who were given several versions of drugs with the xanthine oxidase inhibitor group 64% were allopurinol with patients with the most appropriate indications, the right patient, and the right dose of 96%.
Analisis Interaksi Obat Antihipertensi pada Pasien di Rumah Sakit Umum Royal Prima Marelan Janice Tjandra; Razoki Lubis; Novitaria Br Sembiring
Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan Vol. 3 No. 2 (2025): Juni : Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/corona.v3i2.1310

Abstract

Hypertension is a chronic disease that often attacks the elderly and can cause serious complications, including stroke and heart disease. This study aims to evaluate the use of antihypertensives and analyze drug interactions based on severity in hospitalized patients at RSU Royal Prima Marelan. The research method is descriptive retrospective of patient medical records in 2024. The results showed that the majority of patients were women (62.5%) aged 60–74 years (50%). The use of a combination of two antihypertensive drugs was most commonly found (40%), with the combination of amlodipine and candesartan being the most frequently used. The severity of the most drug interactions was in the moderate category (82.35%), followed by major (10.50%) and minor (7.14%). The most significant interactions occurred in the combination of candesartan and spironolactone (major), and amlodipine and bisoprolol (moderate).
Co-Authors Finna Piska Janice Tjandra Meldawati Novitaria Br Sembiring Olivia Happy Novita Syahratul Hasanah