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All Journal Barigas: Jurnal Riset Mahasiswa
Auliyah, Mayasin Tania
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Uji aktivitas antiglikemik ekstrak kulit labu kuning (Cucurbita moschata) secara in vitro Auliyah, Mayasin Tania; Toemon, Angeline Novia; Martani, Natalia Sri
Barigas: Jurnal Riset Mahasiswa Vol. 1 No. 3 (2023): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v1i3.8055

Abstract

Diabetes Mellitus is a chronic disease with the main symptoms of hyperglycemia. Phytochemical screening of pumpkin skin (Cucurbita moschata) contains alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins which have potential as antiglycemic agents. This study aims to prove the antiglycemic activity of pumpkin peel extract (Cucurbita moschata) which acts as a reducing sugar and binds glucose in vitro using the Nelson Somogyi method. The sample of this study was pumpkin peel extract with concentrations of 60, 80, 100, 120, 140 ppm and 5 ppm quercetin as positive control. Pumpkin peel extract (Cucurbita moschata) has a potention as reducing sugar. The absorbance of each concentration of group 60, 80, 100, 120, 140 ppm is 0.400; 1.100; 1.182; 1.217; 1.505. The statistical test resulted p = 0.039, means the concentration of pumpkin peel extract (Cucurbita moschata) has an effect on decreasing glucose levels and resulted in EC50 = 56.1
Co-Authors Angeline Novia Toemon, Angeline Novia Natalia Sri Martani