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Uji aktivitas antiglikemik ekstrak kulit labu kuning (Cucurbita moschata) secara in vitro Auliyah, Mayasin Tania; Toemon, Angeline Novia; Martani, Natalia Sri
Barigas: Jurnal Riset Mahasiswa Vol. 1 No. 3 (2023): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v1i3.8055

Diabetes Mellitus is a chronic disease with the main symptoms of hyperglycemia. Phytochemical screening of pumpkin skin (Cucurbita moschata) contains alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins which have potential as antiglycemic agents. This study aims to prove the antiglycemic activity of pumpkin peel extract (Cucurbita moschata) which acts as a reducing sugar and binds glucose in vitro using the Nelson Somogyi method. The sample of this study was pumpkin peel extract with concentrations of 60, 80, 100, 120, 140 ppm and 5 ppm quercetin as positive control. Pumpkin peel extract (Cucurbita moschata) has a potention as reducing sugar. The absorbance of each concentration of group 60, 80, 100, 120, 140 ppm is 0.400; 1.100; 1.182; 1.217; 1.505. The statistical test resulted p = 0.039, means the concentration of pumpkin peel extract (Cucurbita moschata) has an effect on decreasing glucose levels and resulted in EC50 = 56.1

Tingkat keparahan penyakit COVID-19 pada penerima vaksin influenza pada pegawai Kejaksaan Tinggi Provinsi Kalimantan Tengah Salsabilah, Alfisa Fitri; Carmelita, Austin Bertilova; Toemon, Angeline Novia
Barigas: Jurnal Riset Mahasiswa Vol. 1 No. 3 (2023): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v1i3.8077

Influenza virus is a common respiratory tract infection with mild to severe clinical manifestations. Influenza and COVID-19 produce similar clinical symptoms and affect the same groups, namely age, gender and high-risk groups. Influenza vaccine effectiveness varies by group by about 40-60%. Individuals who get the influenza vaccine receive protection against COVID-19. The method used for sampling in the population is a simple random sampling method. The total number of respondents is 61 employees of the High Court of Central Kalimantan Province in 2020 and 2021 who have met the inclusion and exclusion criteria. The conclusion of this study is that there is a significant relationship between the administration of the influenza vaccine and the severity of the COVID-19 disease.

Pengaruh Penyuluhan terhadap Tingkat Pengetahuan dalam Pencegahan HIV/AIDS pada Remaja di SMAN-1 Palangka Raya Panueh, Jovanka Mangium Wijayanti; Martani, Natalia Sri; Toemon, Angeline Novia
Barigas: Jurnal Riset Mahasiswa Vol. 2 No. 1 (2024): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v2i1.10465

Human Immunodeficiency Virus (HIV) is a virus that infects cells of immune system, destroys or impairs their function so it can cause progressive damage of the immune system which leads to Acquired Immunodeficiency Syndrome (AIDS). Adolescent knowledge about reproductive health is generally influenced by education, personal experience, culture and mass media. The provision of adequate and factual information about HIV/AIDS allows a teenager to raise awareness, an understanding and behave according to the knowledge they has. The purpose of this study is to determine the effect of counseling on the level of knowledge in preventing HIV/AIDS among students at SMAN-1 Palangka Raya. This study used a Quasy-experimental design, a one group pretest posttest design, with a simple random sampling technique. The data analysis used is the Wilcoxon test. The results showed that the level of knowledge of adolescents about HIV/AIDS at SMAN-1 Palangka Raya before being given counseling was mostly in the less category as many as 57 people (57%), then the level of knowledge of teenagers about HIV/AIDS after being given counseling was mostly in the good category as many as 91 people (91%). There is an influence in the provision of counseling on the level of knowledge of adolescents about HIV/AIDS at SMAN-1 Palangka Raya.

Perubahan tekanan darah dan heart rate recovery pasca olahraga aerobik mix impact (senam dayak) pada mahasiswa Universitas Palangka Raya Steffany Angelina Monica; Balyas , Abi Bakring; Sitompul, Sanggap Indra; Toemon, Angeline Novia; Ahmad, Farah Fauziah Radhiyatulqalbi
Barigas: Jurnal Riset Mahasiswa Vol. 2 No. 3 (2024): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v2i3.12063

One indicator of a person's heart health can be assessed by looking at resting heart rate (HR), resting blood pressure (BP), and cardiac output. Based on data from the Central Kalimantan Provincial Health Office, the prevalence of hypertension in 2019 was 34.47%. This figure shows that hypertension is still above the national average. This study aims to analyze changes in blood pressure and heart rate recovery after mix impact aerobic exercise in the form of dayak gymnastics in Palangka Raya University students. The research design used a descriptive research design using a cross-sectional study design. The subjects were 36 students of the Sendratasik Study Program who met the criteria. The instrument used was the Dayak gymnastics video. Data were analyzed using Univariate and Multivariate. Data analysis was carried out using the Friedman test, for BPs and TDd paired t-test, for heart rate recovery. The decrease in systolic and diastolic blood pressure after doing Dayak gymnastics occurred at minutes 30, 45, and significantly at minute 60 by 6.21/4 mmHg. While the decrease in heart rate recovery after Dayak gymnastics significantly occurred at minute 5 by 22.27 bpm

Hubungan tingkat adiksi gadget dengan kejadian insomnia pada siswa SMPN 1 Palangka Raya Kesuma, I Putu Gede Candra; Balyas, Abi Bakring; Toemon, Angeline Novia
Barigas: Jurnal Riset Mahasiswa Vol. 2 No. 3 (2024): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v2i3.12131

Insomnia is one or more sleep disorders that include difficulty starting sleep, difficulty maintaining sleep so that often waking up from sleep, waking up too early in the morning and difficult to fall back asleep, poor quality sleep. Addiction is a condition in which a person is bound by his habits and will feel difficulty when he will be kept away or released from these activities, the negative impact of addiction gedged this study aims to determine the relationship between the level of addiction and the incidence of insomnia in students of SMPN 1 Palangka Raraya. This research was conducted at SMPN 1 Palangka Raya on October 23, 2023. This research method uses cross sectional, data collection using questionnaires and analytical data using spearman correlation, in this research obtained results from the chi square test and spearman correlation obtained P valule of 0.000 <0.05 and r value of 0.245. In conclusion, there is a relationship with a low correlation strength between addiction and insomnia in SMPN 1 Palangka Raya students.

Peningkatan Pemahaman Osteoporosis pada Wanita di Kelurahan Kereng Bangkirai Kota Palangka Raya Toemon, Angeline Novia; Carmelita, Austin Bertilova; Turnip, Oktaviani Naulita
Jurnal Pengabdian Masyarakat Nusantara (JPMN) Vol. 5 No. 1 (2025): Februari - Juli 2025
Publisher : Lembaga Otonom Lembaga Informasi dan Riset Indonesia (KITA INFO dan RISET)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35870/jpmn.v5i1.3484

Osteoporosis is a disease characterised by a decrease in bone density, leading to the risk of fractures, especially in the elderly and post-menopausal women. Although it can be prevented and managed, many people are not aware of the importance of prevention and early detection of osteoporosis. This community service activity aims to increase community understanding and knowledge related to osteoporosis, as well as provide information on the prevention and management of the disease. This activity was carried out in Kereng Bangkirai village, involving people from various age groups, especially the elderly and post-menopausal women. Activities included counselling on the causes, symptoms, and prevention of osteoporosis, light exercise, and physical examination to detect osteoporosis risk. Evaluation showed a significant increase in participants' knowledge about osteoporosis after participating in this activity. Overall, this activity showed high enthusiasm for the material presented and triggered participants to lead a healthy lifestyle to prevent osteoporosis. This activity has a positive impact in increasing public awareness of the importance of maintaining bone health, and is expected to be held on an ongoing basis to reach more individuals, especially those at high risk.

Evaluation of the combination patch of betel leaf extract (Piper sp.) - ultrasonic assisted extraction as a transdermal delivery system on fibroblast cell formation and collagen density Valencia, Regina; Trinovita, Elsa; Shinta, Herlina Eka; Toemon, Angeline Novia; Ysrafil, Ysrafil
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1687

The combination of red betel (Piper crocatum) and green betel (Piper betle L.) leaves is believed to act synergistically in enhancing wound healing. Transdermal patches offer advantages over conventional topical forms due to their sustained drug release, ease of application, and prolonged therapeutic effect. This study evaluated the histopathological effects of a combination patch containing betel leaf extracts for incision wound treatment in Wistar rats. The studies used an true experimental post-test-only control group design, five groups were tested: a blank patch (K−), a povidone-iodine patch (K+), and combination extract patches at concentrations of 7.5% (K1), 15% (K2), and 30% (K3), applied over 14 days with six animals per group. Patch characteristics were assessed through organoleptic tests, thickness, weight uniformity, folding endurance, and pH, while wound healing was evaluated through histological analysis of fibroblast cell counts and collagen density. Statistical analysis was conducted using the Kruskal-Wallis test followed by Mann-Whitney post-hoc tests. The 30% combination patch (K3) showed the most significant healing effect, with fibroblast counts exceeding 50 cells and dense collagen formation scoring +3. These results indicate that a transdermal patch combining Piper crocatum and Piper betle L. extracts effectively promotes wound healing by enhancing fibroblast proliferation and collagen synthesis.

Karakteristik Pasien Epilepsi di RSUD dr. Doris Sylvanus di Palangka Raya Parhusip, Luther; Tori, Marthin; Br Surbakti, Ranintha; Lestarisa, Trilianty; Toemon, Angeline Novia
Barigas: Jurnal Riset Mahasiswa Vol. 3 No. 1 (2025): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v3i1.11909

electrical charges in neurons in the brain. Globally, an estimated 5 million people are diagnosed with epilepsy each year. In Indonesia until now there is no definite incidence data because many people with epilepsy are not detected or not visit health centers. This study aims to determine characteristics of epilepsy patients based on age, gender, type of epilepsy, education level, occupation, ethnicity, type of medication, and amount of medication in epilepsy patients at Dr. Doris Sylvanus Hospital. Observational descriptive method with retrospective approach, research data were taken from medical record data for epilepsy patients in 2021-2022. In this study, there were 93 epilepsy patients, dominated by the age group <20 years (45%), male gender (51%), not working (74%), high school (37%), Dayak (51%), type of generalized epilepsy (64%), number of monotherapy drugs (58%), type of valproic acid drug (30%). The characteristics of epilepsy patients at RSUD dr. Doris Sylvanus Central Kalimantan in 2021-2022 in the age group <20 years, male, not working, high school, Dayak tribe, general epilepsy type, number of monotherapy drugs with valproic acid type of drug

Presence of Salmonella sp. In Tilapia and Catfish from Cages in Pahandut Seberang Along the Kahayan River Flow Kurniawan, Mutiara; Praja, Rian Ka; Widiarti, Astri; Hanasia, Hanasia; Toemon, Angeline Novia
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.185-191

Salmonellosis is a zoonosis, which means that it may be spread from animals to people through fish meat. It is a sickness brought on by an infection with the salmonella bacteria that infect humans and animals and invade the digestive tract. According to data from the Institute for Health Metrics and Evaluation, the global rate of salmonellosis in 2019 was 4.22 cases per 100,000 people, with a 1.72 fatality rate. Indonesia had a mortality rate of 2.42 and 5.82 per 100,000 people 2019. The objective of this study is to identify Salmonella sp. bacteria in 14 samples of river water, catfish (Clariidae), and tilapia (Oreochromis niloticus) raised in rivers. This study includes two water samples, three catfish samples, and nine tilapia samples from the cage of the Pahandut Seberang River in Palangka Raya City. It employs a descriptive research design using an experimental technique. Among the metrics noted is the detection of Salmonella sp. The study found that all water samples, tilapia, and catfish tested positive for Salmonella sp bacteria in the selective media Salmonella Shigella Agar (SSA), that 14 samples (100%) in the gram staining test displayed the traits of Salmonella sp bacteria, and that 5 samples (B N1, C N2-3 samples in tilapia, B L1 samples in catfish, and water sample 2 showed the type of Salmonella paratyphoid b bacteria) and 9 samples, namely samples Salmonella tyhpimarium bacteria were found in samples A L1, C L1 in catfish, B N2-3, C N1 in tilapia, and water 1. As a result, every sample surpassed the SNI 7388:2009 maximum level of microbial contamination, which is positive/25g. According to the Indonesian National Standardization Agency's SNI 7388:2009 guidelines for the upper limit of microbial contamination in food, the tilapia meat, catfish, and river water in the river cage of Kahayan Pahandut Seberang Palangka Raya City do not satisfy the requirements.

Peningkatan Pemahaman Osteoporosis pada Wanita di Kelurahan Kereng Bangkirai Kota Palangka Raya Toemon, Angeline Novia; Carmelita, Austin Bertilova; Turnip, Oktaviani Naulita
Jurnal Pengabdian Masyarakat Nusantara (JPMN) Vol. 5 No. 1 (2025): Februari - Juli 2025
Publisher : Lembaga Otonom Lembaga Informasi dan Riset Indonesia (KITA INFO dan RISET)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35870/jpmn.v5i1.3484

Osteoporosis is a disease characterised by a decrease in bone density, leading to the risk of fractures, especially in the elderly and post-menopausal women. Although it can be prevented and managed, many people are not aware of the importance of prevention and early detection of osteoporosis. This community service activity aims to increase community understanding and knowledge related to osteoporosis, as well as provide information on the prevention and management of the disease. This activity was carried out in Kereng Bangkirai village, involving people from various age groups, especially the elderly and post-menopausal women. Activities included counselling on the causes, symptoms, and prevention of osteoporosis, light exercise, and physical examination to detect osteoporosis risk. Evaluation showed a significant increase in participants' knowledge about osteoporosis after participating in this activity. Overall, this activity showed high enthusiasm for the material presented and triggered participants to lead a healthy lifestyle to prevent osteoporosis. This activity has a positive impact in increasing public awareness of the importance of maintaining bone health, and is expected to be held on an ongoing basis to reach more individuals, especially those at high risk.

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