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All Journal Jurnal Administrasi Kesehatan Indonesia Majalah Obat Tradisional Pharmascience Jurnal Surya Medika Meditory : The Journal of Medical Laboratory Herb-Medicine Journal Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Kedokteran Universitas Palangka Raya Jurnal Insan Farmasi Indonesia Journal of Experimental and Clinical Pharmacy (JECP) Pengabdian Kampus: Jurnal Informasi Kegiatan Pengabdian Pada Masyarakat Kontribusi: Jurnal Penelitian dan Pengabdian Kepada Masyarakat JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Farmasi Indonesia Barigas: Jurnal Riset Mahasiswa Jurnal Media Analis Kesehatan Tropis: Jurnal Riset Teknologi Laboratorium Medis
Natalia Sri Martani
Departemen Mikrobiologi Fakultas Kedokteran Universitas Palangka Raya, Palangka Raya, Kalimantan Tengah, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

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Pemanfaatan Penawar Sampai (Tinospora crispa L.) sebagai Tanaman Obat Tradisional oleh Suku Dayak Ngaju Natalia Sri Martani; Fatmaria Fatmaria
Jurnal Pharmascience Vol 7, No 2 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.8799

Abstract

 Kehidupan sub rumpun Suku Dayak Ngaju di Kalimantan Tengah sangat bergantung pada hutan dan alam. Masyarakatnya menggunakan berbagai obat-obatan tradisional yang bermanfaat, salah satunya adalah tanaman penawar sampai (Tinospora crispa L.). Penelitian ini bertujuan mengeksplorasi tanaman T. crispa sebagai obat tradisional Suku Dayak Ngaju. Metode yang digunakan ialah penelitian eksploratif dari Basir, para ahli pengobatan tradisional Suku Dayak Ngaju. Pemilihan Basir menggunakan metode snowball sampling. Hasil penelitian ini menunjukkan bahwa T. crispa yang digunakan oleh masyarakat Suku Dayak Ngaju secara empiris digunakan sebagai antihipertensi; menunjang diabetes agar terkontrol; pengobatan penyakit kulit; melawan alergi; meningkatkan selera makan; penyembuhan luka; sakit kuning (hepatitis); penyembuhan rematik; antimalaria; menstimulasi saraf; dan antidiare. Kesimpulan penelitian ini bahwa T. crispa merupakan tanaman obat tradisional yang memiliki banyak manfaat. The life of the sub ethnic of Dayak Ngaju Tribe in Central Kalimantan is very dependent on the forest and nature. People use a variety of traditional medicines are beneficial, one of which is the penawar sampai (Tinospora crispa L.). The research objective to explore the utilization of the T. crispa as a medicinal plant traditional Dayak Ngaju Tribe. The method used is exploratory research of Basir, the traditional healers from Dayak Ngaju Tribe. The selection of Basir using the method of snowball sampling. The results of this study indicate that the antidote to that used by the people of Dayak Ngaju Tribe empirically used as an antihypertensive; support to controlled diabetes; a skin disease that can be treated; fight allergies; improves appetite; wound healing; yellow fever (hepatitis); the healing of rheumatism; antimalaria; stimulates the nerves and anti diarrhea. The conclusion of this study that the antidote to is a traditional medicinal plant that has many benefits.Keywords: Penawar Sampai, Tinospora crispa L., Medicinal Plants, Dayak Ngaju Tribe
COMMUNITY KNOWLEDGE, ATTITUDES, AND BEHAVIOR TOWARDS SOCIAL DISTANCING POLICY AS PREVENTION TRANSMISSION OF COVID-19 IN INDONESIA Budi Yanti; Eko Mulyadi; Wahiduddin Wahiduddin; Revi Gama Hatta Novika; Yuliana Mahdiyah Da'at Arina; Natalia Sri Martani; Nawan Nawan
Indonesian Journal of Health Administration (Jurnal Administrasi Kesehatan Indonesia) Vol. 8 No. 2 (2020): SPECIAL ISSUE
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jaki.v8i2.2020.4-14

Abstract

Background: Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV2 recently became a pandemic worldwide, such as in Indonesia. Social distancing is one of the recommended mitigations to reduce the risk of disasters, such as morbidity and mortality caused by COVID-19. Community compliance with social distancing is a part of the pandemic control.Aims: This study identified knowledge, attitudes, and behavior towards the prevention of SARS-CoV-2 transmission through social distancing during COVID-19 pandemic among Indonesian community.Methods: This descriptive study applied a cross-sectional design and distributed closed questions with online  questionnaire randomly to 34 provinces in Indonesia on social media networks and e-mail. This study successfully collected 1,102 respondents from 29 provinces in Indonesia. The data were analyzed descriptively by calculating frequency, percentage, and cross-tabulation.Results: This study had successfully identified  99%, 59%, and 93% of respondents with good knowledge, positive attitudes, and good behavior respectively towards  social distancing. Among the respondents who had good knowledge showed positive attitudes (58.85%) and good behavior (93.3%). The respondents who had positive attitudes showed good behavior (96.7%).Conclusion: Indonesian community had good knowledge, attitude and behavior towards social distancing as a way to prevent the virus transmission. This strongly supports disaster mitigation in controlling the COVID-19 pandemic in Indonesia. Keywords: attitudes, behavior, COVID-19, knowledge, social distancing.
Literature Review: Analisis Senyawa Aktif Ekstrak Dan Fraksi Tanaman Berpotensi Sebagai Antiplatelet Virena Audelia Rambang; Fatma Ria; Natalia Sri Martani
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 3 (2021): Herb-Medicine Journal Juli 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i3.9436

Abstract

ABSTRACT Stroke is still the main cause of morbidity and mortality in the world. Research found "aspirin resistant" in 5-60% of cases, it’s necessary to develop researches related to antiplatelet therapy. In the antiplatelet research on plant extracts, some were significant and some weren’t. To determine active compound of plant extracts, fractions, mechanism of action, extraction method, isolation methods of active compounds with antiplatelet activity. Literature studies with a systematic approach, data from original articles in GoogleScholar, PubMed. Obtained 32 literatures through data quality analysis and topic suitability. Data synthesis using PICO method. 30 journals significantly have antiplatelet activity, 2 weren’t, the most found compounds were flavonoids, quercetin. Mechanism of action as an antiplatelet, antithrombotic. Extraction methods maceration, reflux, juice, sonication, soxhlet, distillation. The isolation methods using CC, HPLC, TLC, NMR. Conclusion: Insignificant results are from AGE and raw, boiled, fried garlic, both tested in vivo. Journals that significantly have antiplatelet results are from extracts of strawberries, grape seeds, Allium sp., Bay leaves, mango peel, tomatoes, Hawthorn, C.aromatica Salisb., Red ginger, G.verrucosa, S.polycystum, olive leaves, M.alba, P.baumii, R.vernicflua, A.shikokiana, katuk leaves, tempuyung leaves, red cabbage, M.obovata, lempeni leaves, kajajahi leaves, starfruit leaves, U.macrocarpa, M.citrifolia, C.limon, L.japonica, E.bicyclis, S.deserta, V.labrusca. Most found active compound with antiplatelet activity are flavonoids, fraction quercetin. Mechanism of action on COX-1, AA, TXA2, P13K pathways, increased cAMP, VASP stimulation. Extraction methods by maceration, reflux, soxhlet, sonication, juice, distillation. Isolation methods using CC, HPLC, TLC, NMR
Antibacterial activity of extract sangkareho leaves (Callicarpa longifolia LAM.) on Salmonella typhi and Staphylococcus epidermidis Silvani Permatasari; Ervi Audina Munthe; Muntir Guru Singa; Elsa Trinovita; Ratna Widayati; Natalia Sri Martani; Anna Marthea Veronica
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art7

Abstract

Background: The most commonly found disease-causing microorganisms are the Salmonella typhi and Staphylococcus epidermidis bacteria. S.typhi is a gram-negative bacterium that causes typhoid fever, and S.epidermidis is a gram-positive bacterium that attacks mucous membranes and human skin. Sangkareho (Callicarpa longifolia Lam.) is one of the indigenous herbal plants of Central Kalimantan, which is empirically used as a wound medicine, diarrhea, diabetic, anti-inflammatory, and can be an antibacterial agent.Objective: This study used six groups are concentrations of 10%, 25%, 50%, and 100%, Chloramphenicol as a positive control, and dimethyl sulfoxide (DMSO) as a negative control. Methods: The method used for this test is the well diffusion method. In Nutrient Agar (NA) media, holes were made to insert 40 μl of each extract concentration, positive and negative control with four repetitions, then incubated for 18-24 hours at 37ºC. Data analysis using the One Way Anova test.Results: The research findings showed that ethanol extract of sangkareho leaves with all concentrations had an inhibitory effect against both bacteria tested.Conclusion: The ethanol extract of sangkareho leaves at the concentration of 10% was found to be the optimum and at the concentration of 100% was the maximum effectiveness for inhibiting S. typhi and S. epidermidis.
Identifikasi Bakteri pada Alat-Alat Medis Bedah Minor di Ruang UGD Puskesmas Pahandut Kota Palangka Raya: Identification of Bacteria on Minor Surgical Medical Devices in the er of Pahandut Public Helath Center Palangka Raya Sherly Marselina; Natalia Sri Martani; Silvani Permatasari
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.5673

Abstract

Background: HAIs are infections that are obtained from hospitals or other health care facilities, such as health centers. According to the Ministry of Health, in Indonesia it reaches 15.74%, much higher than in developed countries, which ranges from 4.8 to 15.5%. According to the Indonesian Ministry of Health, the average is 8.1%. At the Puskesmas, the Emergency Unit (ER) is the place most at risk for HAIs, for patients undergoing treatment using less sterile equipment, such as minor surgical equipment. Object: To determine the presence or absence of bacteria and to identify the types of bacteria in minor surgical medical devices in the ER Pahandut Public Health Center, Palangka Raya City. Methods: This study used a descriptive quantitative design method, to determine the presence or absence of bacteria in sterilized minor surgical medical devices. Results: The identification results found gram-positive bacteria in 3 samples of minor surgical instruments, namely 2 samples identified as Staphylococcus aureus and 1 sample identified as Streptococcus sp. Conclusion : There are bacterial contaminants in minor surgical medical devices used in the ER Pahandut Public Health Center, Palangka Raya City.
SKRINING FITOKIMIA DAN UJI ANTIBAKTERI EKSTRAK ETANOL DAUN HANJUANG MERAH (Cordyline fruticose) TERHADAP BAKTERI Staphylococcus epidermidis Ayuchecaria, Noverda; Sri Martani, Natalia; Kartika Komara, Nisa; Chuchita; Pereiz, Zimon; Oksal, Efriyana
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1683

Abstract

Hanjuang Merah (Cordyline fruticosa) is one of the plants used by the Dayak people as traditional medicine. Red hanjuang is an ornamental plant that is very abundant in Indonesia, but there is still not much research that proves the efficacy of red hanjuang. The aim of this research was to determine the phytochemical screening and antibacterial activity of leaf extract of hanjuang merah (Cordyline fruticose) against the bacteria Staphylococcus epidermidis. The method used in sample extraction was maceration, while in the antibacterial test used the paper strip diffusion method with concentrations of 25%, 50%, 75% and 100%. The yield of ethanol extract of hanjuang merah leaf was 11.35%. There was an increase in the diameter of the inhibition zone with the addition of the concentration of ethanol extract of hanjuang merah leaf. The addition of ethanol extract of hanjuang merah leaf at a concentration of 75% sensitive inhibited the growth of Staphylococcus epidermidis bacteria. Secondary metabolites such as tannins, alkaloids, saponins, flavonoids and quinones found in ethanol extract of hanjuang merah leaves are considered responsible for inhibiting the growth of Staphylococcus epidermidis bacteria.
Uji Aktivitas Antibakteri Sediaan Gel Ekstrak Daun Sungkai (Peronema Canescens Jack) terhadap Streptococcus pyogenes Secara In Vitro Trinovita, Elsa; Fiska, Friskilla Andia; Martani, Natalia Sri
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 16 No. 1 (2024): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v16i1.211

Abstract

Impetigo merupakan penyakit yang sering menyerang anak-anak yang disebabkan oleh infeksi bakteri Streptococcus pyogenes. Meningkatnya resistensi bakteri terhadap antibiotik merupakan peluang besar untuk memanfaatkan senyawa metabolit sekunder pada tanaman di Indonesia khususnya yang tumbuh di Kalimantan Tengah yaitu daun sungkai (Peronema canescens Jack). Daun sungkai (Peronema canescens Jack) memiliki senyawa metabolit sekunder yaitu flavonoid, alkaloid, fenolik, saponin, tanin, steroid dan triterpenoid yang dapat menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri sediaan gel ekstrak daun sungkai (Peronema canescens Jack) terhadap Streptococcus pyogenes. Proses ekstraksi daun sungkai dilakukan dengan menggunakan metode maserasi dengan pelarut etanol 96%. Beberapa kelompok perlakuan pada penelitian ini adalah kelompok gel daun sungkai 2%(F1), 4%(F2), 8%(F3), kelompok positif (Mupirocin 2%) dan kelompok negatif (Na-CMC 1%). Lalu dilakukan uji evaluasi sifat fisik sediaan gel meliputi uji organoleptis, pH, homogenitas, daya sebar, dan daya lekat. Evaluasi pada aktivitas antibakteri pada Streptococcus pyogenes menggunakan metode sumuran dengan mengukur diameter pada zona hambatHasil penelitian ini menunjukkan seluruh kelompok formulasi sediaan gel ekstrak daun sungkai (Peronema canescens Jack) memenuhi syarat uji evaluasi sifat. Kelompok F3 (konsentrasi 8%) menunjukklan aktivitas antibakteri dengan diameter zona hambat terbesar yaitu rata-rata zona hambat dengan diameter 19,18 mm. Hal ini dapat disimpulkan bahwa sediaan gel ekstrak daun sungkai (Peronema canescens Jack) memiliki aktivitas antibakteri dalam menghambat pertumbuhan Streptococcus pyogenes.
Studi In Vitro Aktivitas Antibakteri Ekstrak Etanol Penawar Sampai (Tinospora crispa L.) terhadap Staphylococcus epidermidis Martani, Natalia Sri; Turnip, Oktaviani Naulita; Hanasia, Hanasia; Nawan, Nawan
Journal of Experimental and Clinical Pharmacy (JECP) Vol 4, No 2 (2024): August 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v4i2.1074

Abstract

Kulit merupakan jaringan terluar di tubuh manusia yang menjadi pertahanan pertama dari masuknya patogen. Kulit dihuni oleh berbagai flora normal, salah satunya adalah Staphylococcus epidermidis. S. epidermidis adalah patogen oportunistik yang menjadi penyebab infeksi nosokomial yang menetap pada perangkat medis. Kasus infeksi nosokomial banyak terjadi baik di negara maju maupun negara berkembang. Infeksi nosokomial karena S. epidermidis tergolong sulit diatasi karena adanya kemampuan spesies ini dalam membentuk biofilm dan resistensi antibiotik yang menyebabkan kasus nosokomial berujung kematian. Penelitian ini mengujikan ekstrak dari tanaman penawar sampai atau brotowali terhadap S. epidermidis guna mendeteksi adanya aktivitas antibakteri. Batang penawar sampai dimaserasi dan diuapkan menjadi ekstrak kental dengan konsentrasi 20, 50, 75, dan 100%. Ekstrak kental batang penawar sampai diujikan terhadap S. epidermidis dengan metode difusi cakram. Interpretasi kemampuan ekstrak dalam menekan pertumbuhan S. epidermidis dapat diamati dari diameter zona hambat yang terbentuk di sekitar cakram. Konsentrasi terendah dalam menekan pertumbuhan S. epidermidis dihasilkan pada penelitian ini adalah konsentrasi ekstrak 20%. Hal ini mengindikasikan adanya potensi dari ekstrak penawar sampai sebagai antibakteri terhadap S. epidermidis yang tergolong dalam bakteri Gram positif.The skin is the outermost tissue in the human body and the first line of defense against pathogen entry. The skin is inhabited by a variety of normal flora, one of which is Staphylococcus epidermidis. S. epidermidis is an opportunistic pathogen that causes nosocomial infections that persist in medical devices. Cases of nosocomial infections are common in both developed and developing countries. Nosocomial infections due to S. epidermidis are relatively difficult to overcome due to the ability of this species to form biofilms and antibiotic resistance which causes nosocomial cases to lead to death. This study tested extracts from the antidote to brotowali plant against S. epidermidis to detect antibacterial activity. The stem was macerated and evaporated into thick extracts with concentrations of 20%, 50%, 75%, and 100%. The thick extracts were tested against S. epidermidis using disc diffusion method. Interpretation of the ability of the extract to suppress the growth of S. epidermidis can be observed from the diameter of the inhibition zone formed around the disc. The lowest concentration in suppressing the growth of S. epidermidis produced in this study was 20% extract concentration. This indicates the potential of the extract as an antibacterial against S. epidermidis which is classified as Gram-positive bacteria.
Antibacterial Activity of Pasak Bumi Stem (Eurycoma longifolia J.) Extract against Salmonella typhi Sirait, Christine; Hanasia, Hanasia; Martani, Natalia Sri; Ysrafil, Ysrafil; Fatmaria, Fatmaria
Majalah Obat Tradisional Vol 29, No 2 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.91168

Abstract

Typhoid fever is caused by consuming food or water contaminated with Salmonella typhi. The disease develops from bacterial infection through the consumption of contaminated sustenance and drink. The bacterium can cause bacteremia, which is bacteria living in the blood, penetrating the mucosal epithelium of the small intestine and entering the lymphatic flow. Therefore, this study aimed to assess the potential inhibitory effect of ethanol extracts derived from stems of Eurycoma longifolia (pasak bumi) on the growth of Salmonella typhi bacteria. Compounds such as alkaloids, saponins, flavonoids, terpenoids, and tannins in pasak bumi stems possessed antibacterial properties. Extracts were made using 96% ethanol at varying concentrations (10%, 20%, 30%, 40%, 50%) with distilled water and chloramphenicol as negative and positive control. The result showed that pasak bumi stem extracts inhibited Salmonella typhi, with increasing efficacy at higher concentrations and statistical analysis reported significant differences between all treatment groups (p<0.001). Average zone diameter was 0 mm and 23.10 mm for negative and positive control, as well as 2.75 mm, 4.10 mm, 5.24 mm, 6.98 mm, and 8.55 mm for 10%, 20%, 30%, 40% and 50% extracts, respectively. This study provided verification of antibacterial effects of pasak bumi stem ethanol extracts against Salmonella typhi.
Perbedaan tingkat pengetahuan tentang kesehatan reproduksi pada mahasiswa Fakultas Kedokteran, Fakultas Hukum dan Fakultas Ekonomi Universitas Palangka Raya Panjaitan, Gabrielle Angelique; Adnyana, I Gde Hary Eka; Astrid Teresa; Natalia Sri Martani; Dian Mutiasari
Barigas: Jurnal Riset Mahasiswa Vol. 1 No. 2 (2023): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v1i2.7914

Abstract

Knowledge about sexual and reproductive health such as sexually transmitted infections has a huge influence all over the world. Seeing cases related to reproductive health in indonesia is still relatively high both among men and women. This study was conducted to see how different levels of knowledge in the field of reproductive health in students of the FK, FH and FE. This study uses descriptive Analytical Study type with cross sectional method. Data collection was done by using questionnaires that have been tested for validity and reliability, after that univariate analysis and data processing with computerization. This study obtained the results for, the level of knowledge of students of the FK is good 97.7%, students of the FH is good knowledge of 75.5%, while students of the FE are 55.4%. It can be concluded that there is a difference in the level of knowledge between the students of the FK, FH, and FE, where it can be seen that the best level of knowledge is the students of the FK, followed by students of the FH, and sufficient level of knowledge is the students of the FE.
Co-Authors Adelia, Sirli Adnyana, I Gde Hary Eka Angeline Novia Toemon, Angeline Novia Anhar, Khansa Hanifah Anna Marthea Veronica Arif Rahman Jabal Arini Ratnasari ASTRID TERESA Augustina , Indria Auliyah, Mayasin Tania Ayuchecaria, Noverda Budi Yanti Chuchita Dian Mutiasari Eko Mulyadi Elsa Trinovita Ervi Audina Munthe Fatma Ria Fatmaria Fatmaria Fatmaria, Fatmaria Fiska, Friskilla Andia Furtuna, Dewi Klarita Hanasia Hanasia, Hanasia Hertanto, Bima Adithya Manalu, Rosmaryati Muhammad Jafar, Muhammad Muntir Guru Singa Nawan Nawan Nawan Nawan, Nawan Nazhifah, Annida Kholifatun Nisa Kartika Komara Oksal, Efriyana Panjaitan, Gabrielle Angelique Panueh, Jovanka Mangium Wijayanti Patricia, Tisha Permatasari, Silvani Puspita Sari, Dewi Marta Putri Welmart, Devina Vania Ranintha br Surbakti Ratna Widayati Revi Gama Hatta Novika Rian Ka Praja Saputra, Aldi Aditya Sherly Marselina Silalahi, Angelina Brigitta Darawulan Silvani Permatasari Sirait, Christine Teresa, Astrid Tri Widodo Turnip, Oktaviani Naulita Virena Audelia Rambang Wahiduddin Wahiduddin Widayati, Ratna Ysrafil, Ysrafil Yuliana Mahdiyah Da'at Arina Zimon Pereiz