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All Journal Respiratory Science Barigas: Jurnal Riset Mahasiswa
Parhusip, Mual Bobby Enrico
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Literatur review : hubungan eosinofil pada kejadian asma akut Fatmawati; Fatmaria; Parhusip, Mual Bobby Enrico
Barigas: Jurnal Riset Mahasiswa Vol. 1 No. 3 (2023): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v1i3.8176

Abstract

An increase in the number of eosinophils in the airways is a pathological feature of asthma. Airway eosinophils are frequently associated with poor lung function measurements. This study is a literature review type which aims to find out whether there is a relationship between eosinophils in the incidence of acute asthma. The method in this study uses a Systematic Literature Review. Source of data obtained from research journals. The journals obtained were 9 national journals and 6 international journals. The results obtained were 9 journals (60%) which agreed that there was a relationship between eosinophils in the incidence of acute asthma. Whereas 6 (40%) journals said it was not related, one of the factors that could occur was because the patient arrived late so that when the eosinophil examination in the blood decreased and infiltration into the tissues had occurred, besides that it was also considered the presence of comorbidities in asthma sufferers.
The Relationship of Serum Zinc Levels and Clinicopathological Characteristics in Individuals with Lung Cancer Haryati, Haryati; Eko Prasetyo, Nugroho; R. Simarmata, Eviriana; Parhusip, Mual Bobby Enrico; Arganita, Fidya Rahmadhany; Humaira, Adhwa
Respiratory Science Vol. 5 No. 1 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i1.143

Abstract

Background: Lung cancer is one of the main contributors to malignancy and leads to the patient's death. The immune system, genetics, and inflammation affect lung cancer progression. Zinc (Zn) is an essential mineral; a Zn deficiency increases the tumor suppressor's expression, damaging deoxyribonucleic acid (DNA) repair ability in tumor growth. The study focused on establishing a relationship between serum Zn levels and lung cancer patients' clinicopathologic characteristics. Method: Thirty-five patients diagnosed with lung cancer were part of the study. The study collected clinicopathological data and serum Zn levels at the initial diagnosis. Serum Zn insufficiency is characterized by a below 80 μg/dL serum Zn level. Results: The median Zn level in our study was 65 μg/dL (range=56.5-73 μg/dL). Serum Zn deficiency was observed in 91.4% of patients, particularly those who had a smoking history, advanced stage, or had hypoalbuminemia. The low-level group exhibited significantly lower albumin concentrations (3.06 g/dL vs. 3.66 g/dL; P=0.024) than the normal group. Conclusion: Most patients with lung cancer at initial diagnosis had a deficiency in Serum Zn, which was associated with hypoalbuminemia.
Co-Authors Arganita, Fidya Rahmadhany Eko Prasetyo, Nugroho Fatmaria Fatmawati Fatmawati Haryati Haryati Humaira, Adhwa R. Simarmata, Eviriana