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ANOSMIA SYMPTOMS AND RT-PCR SWAB RESULTS IN COVID-19 DIAGNOSTICS Lusida, Vincent Geraldus Enoch; Limawan, Denillia; Arifin, Fabilla Faiz; Utami, Nabilah Puspa; Kesuma, Raudhatuzzahra; Qonitatillah, Jihan; Amatullah, Nida` Fahima; Prajitno, Subur
Journal of Community Medicine and Public Health Research Vol. 3 No. 1 (2022): Journal of Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (253.361 KB) | DOI: 10.20473/jcmphr.v3i1.28915

Abstract

Coronavirus Disease-19 (Covid-19) is an infectious disease that has become a pandemic since March 11, 2020. PCR (Polymerase chain reaction) swab is a definitive diagnostic tool for Covid-19, because it has a high level of sensitivity and specificity. One of the symptoms of this infection is anosmia. This study aimed to determine the relationship between the symptoms of anosmia and the positive RT-PCR swab results in Covid-19 diagnostics. This study used a systematic review and meta-analysis method that was in accordance with PRISMA. From 16 articles that met the inclusion and exclusion criteria, we selected 12 articles through EPHPP that reported smell disorder among Covid-19 patients. Four reports studied whether smell disorder was independently associated with Covid-19 diagnosis. The frequency of anosmia ranged between 7,5-95%. Anosmia has high specificity for detecting Covid-19 but has low sensitivity. There was a strong relationship between anosmia symptoms and positive RT-PCR swab results. This showed that anosmia can be a marker for patients to carry out further investigations.
Effectiveness of Zinc Therapy with Zinc-Probiotic Combination Therapy on the Duration of Diarrhea During Hospitalization at Mawaddah Medika Hospital in October - December 2023 Rosyid, Riga Abida; Arifin, Fabilla Faiz; Kristanto, Andika Yudha
Golden Ratio of Data in Summary Vol. 5 No. 2 (2025): February - April
Publisher : Manunggal Halim Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52970/grdis.v5i2.1106

Abstract

Diarrhea is the third leading cause of death among children under five years old worldwide, with improper management both at home and in healthcare facilities being the primary cause. The World Health Organization (WHO) recommends zinc supplementation as a treatment for acute diarrhea, while probiotics, commonly used alongside fluid rehydration, are not yet included in WHO guidelines. This study used a single-blinded randomized Controlled Trial design to compare the effectiveness of zinc therapy versus a combination of zinc and probiotics on the duration of diarrhea during hospitalization at Mawaddah Medika Hospital. Children suffering from diarrhea who met specific inclusion and exclusion criteria were randomly assigned to two groups: one received zinc therapy, while the other received a combination of zinc and probiotics, along with standard treatments. The data were analyzed using the Mann-Whitney test. Eighty children participated in the study, with the majority (60.0%) aged 1-5 years, and 53.8% of the children were male. In the group receiving zinc therapy, diarrhea was approximately 8.54 hours shorter than in the zinc-probiotic combination group. However, the analysis revealed no significant difference in the duration of diarrhea between the two treatments (p > 0.05). Consequently, while no significant difference was found between zinc supplementation and zinc-probiotic combination therapy regarding the duration of diarrhea, further research is needed to explore the administration of these treatments in diarrhea patients.