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All Journal Majalah Obstetri dan Ginekologi Medica Hospitalia
Putra, Very Great Eka
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Incidence of radiation proctitis in cervical cancer receiving radiation therapy at Dr. Kariadi Hospital, Semarang, Indonesia Mirza Iskandar, Teuku; Kristiawan, Endy Cahyono; Faizal, Teuku Rendiza; Ambari, Ediwibowo; Putra, Very Great Eka; Achmad, Lubena
Majalah Obstetri & Ginekologi Vol. 31 No. 3 (2023): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V31I32023.123-128

Abstract

HIGHLIGHTS Radiation proctitis is a post-radiotherapy concern, urging research to reduce its occurrence and improve the well-being of patients. Radiotherapy is the primary treatment for advanced cervical cancer, offering hope and preserving quality of life for patients.   ABSTRACT Objective: To determine the incidence of radiation proctitis in cervical cancer patients after radiation at Dr. Kariadi Hospital, Semarang, Indonesia. Materials and Methods: A descriptive analytic study on 356 cervical cancer patients who received radiation therapy at Dr. Kariadi Hospital Semarang from January 2017 to December 2018 who met the inclusion criteria. Factors assessed included age, BMI, hematologic, stage, histopathology, history of radical hysterectomy surgery and duration of radiation. Cervical cancer staging was assessed using FIGO 2018. Statistical analysis was performed using Mann Whitney with a significant value of p <0.05. Results: From the Chi-square analysis, the relationship between radiation period (less than 56 days and more than 56 days)  (p=0.164), the relationship between age ≥45 and the incidence of proctitis (p=0.208), BMI ≥25 and the incidence of proctitis (p=0.838), Hb <10 with the incidence of proctitis (p=0.492), parity ≤1 with the incidence of proctitis (p=0.137), the relationship between the histopathological examination results with the incidence of proctitis (p=0.253), and stage level with the incidence of proctitis (p=0.226) were not significant. The highest incidence of proctitis occurred in stage 3B of the cervical cancer patients (14.5%). Conclusion: The prevalence of proctitis in cervical cancer patients for the period 2017-2018 was 15.4%. Age, histopathological appearance, stage, history of anemia, history of radical surgery and appearance of symptoms after surgery with symptoms of proctitis did not show a significant relationship.
Correlation between referral type (emergency vs scheduled) and maternal perinatal outcome in suspected placenta accreta spectrum : a retrospective cohort study in Dr.Kariadi hospital Semarang 2020-2023 Umami, Hayyina Maslikhatul; Cahyanti , Ratnasari Dwi; Tjahjanto, Hary; Hadijono, Soerjo; Dewantiningrum, Julian; Putra, Very Great Eka
Medica Hospitalia : Journal of Clinical Medicine Vol. 13 No. 1 (2026): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v13i1.1366

Abstract

BACKGROUND : Maternal Mortality Rate (MMR) in Indonesia at 2023 was 189 over 100.000 live births. The most popular reason for maternal death was obstetrics hemorrhage. Obstetric hemorrhage can be caused by abnormal placentation. Abdominal delivery by cesarean section has increased recently in Indonesia. Cesarean section will increase the risk for placenta accreta spectrum, which raises maternal morbidity and mortality. AIM : To analyze the correlation of emergency and scheduled referral with maternal and perinatal outcomes of suspected placenta accreta spectrum patients in Dr.Kariadi Hospital Semarang 2020 – 2023.METHODS : A cohort retrospective study performed in May 2024, involved 153 women with suspected placenta accreta spectrum were referred to Dr.Kariadi Hospital Semarang in 2020 – 2023, divided by emergency referral and scheduled referral groups. We use Placenta Accreta Index (PAI) Score and all patients who fulfilled the criteria of the placenta accreta spectrum based on FIGO to predict suspicious placenta accreta spectrum. Descriptive analysis included the base characteristics of the patients. Correlation analysis with maternal and perinatal outcomes using Chi Square analyze of SPSS 25.00 version.RESULTS : A total of 69 patients with emergency referrals and 84 patients with scheduled referrals. Mean age was 32.97, median 32(24-44), median of gestation was 3(1-6) and 3(1-9), median of gestational age was 35(22-41) and 36(32-39). The emergency referral had a higher risk for cesarean hysterectomy with OR (95%CI) 2.92 (1.51–5.67), for maternal hemorrhage with OR (95%CI) 2.34 (1.22–4.49), for blood transfusion with OR (95%CI) 6.02 (2.46–14.76), for intensive care admission with OR (95%CI) 4.39 (1.5–12.79), for prematurity with OR (95%CI) 2.56(1.32–4.92), for asphyxia with OR (95%CI) 3.41(1.56–7.47). There were significant differences between emergency and scheduled referrals for vaginal delivery (p=0.03), and perinatal mortality (p=0.04). Estimated blood loss was 1453.7± 1253.6 ml in emergency referral and 878.3 ± 823.7 ml in scheduled referral.CONCLUSION : Emergency referrals had worse maternal and perinatal outcomes than scheduled referrals for suspicious placenta accreta spectrum patients.
Co-Authors Achmad, Lubena Cahyanti , Ratnasari Dwi Ediwibowo Ambari Faizal, Teuku Rendiza Hary Tjahjanto Julian Dewantiningrum Kristiawan, Endy Cahyono Mirza Iskandar, Teuku Soerjo Hadijono Umami, Hayyina Maslikhatul