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All Journal Jurnal Kedokteran Diponegoro Community Development Journal: Jurnal Pengabdian Masyarakat
Ardiansyah, Revi
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Humanities Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Public Health

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The Effect of Lemon Skin Extract on Uric Acid Levels of Hyperuricemia Male Wistar Rats Ardiansyah, Revi; Wijayahadi, Noor; Mahati, Endang; Nindita, Yora
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 2 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i2.43036

Abstract

Background: Purine metabolism, carried out in the liver, results in the production of uric acid. Hyperuricemia is a condition of elevated level of uric acid in the blood that can lead to gout if untreated. Lemon (Citrus Limon.) contains flavonoids which act as antioxidants and have the potential role as antihyperuricemia. Aim: To determine the effect of lemon peel extract on uric acid levels. Methods: Thirty-six male wistar rats from Farmhouse Ungaran were randomly divided into 6 groups, consists of healthy control group (K0), hyperuricemic control (K1), allopurinol control (K2), and 3 treatment groups (P1, P2, P3). Hyperuricemia induced with administration of block broth and potassium oxonate for 4 weeks. Lemon peel extract doses of 17,5, 35, and 70 mg/kg BW, and allopurinol 90 mg/kg BW was given orally for 2 weeks. Statistical analysis was conducted to evaluate differences among groups before and after the intervention. Results: There was a significant difference (p<0,05) in uric acid levels before and after intervention of lemon peel extract in groups K1, K2, and P3. Meanwhile, in groups K0, P1, and P2, there were no significant differences observed. In the pre-test uric acid levels, there was a significant difference (p<0,05) between the K0 group and K1, K2, P1, P2, and P3. Conclusion: There were no significant differences observed in the uric level acid of the treatment and control group after intervention, but there were significant differences in the effects of graded dosages between the treatment groups. 
OPTIMALISASI PROGRAM BIORAMA MELALUI PERANCANGAN BRAND IDENTITY DAN MEDIA BRANDING SEBAGAI PENGEMBANGAN PARIWISATA SEJARAH KOTA PURWOKERTO Suryani, Riri Irma; Setyoko, Adnan; Yudianto, Robert Hendra; Ardiansyah, Revi
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 6 (2024): Vol. 5 No. 6 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i6.40182

Abstract

BIORAMA merupakan program cipta ruang atau placemaking yang menghadirkan berbagai macam produk UMKM organik dan berbagai macam aktivitas kreatif. BIORAMA hadir untuk pertama kali sebagai alternatif solusi wisata sejarah kota Purwokerto yang dilaksanakan satu hari setiap dua kali dalam sebulan. BIORAMA lahir dengan konsep creative market, mini workshop, experience dan walking tour yang pelaksanaannya berlokasi di Gedung Karesidenan Bakorwil. Selain program creatif placemaking, BIORAMA juga mengembangkan program perancangan aset-aset bangunan bersejarah Purwokerto kedalam berbagai rancangan desain seperti desain sign system gedung-gedung bersejarah, perancangan animasi infografis gedung bersejarah dan guide map gedung bersejarah yang ada di Purwokerto. Dalam perancangan ruang kreatif BIORAMA menggunakan metode penelitian kualitatif dan analisis data 5W+1H (what, where, who, when, why and How) dalam pengolahan data observasi dan wawancara yang telah di dapatkan. Penelitian yang dilakukan dengan desain brand identity dan media promosi BIORAMA dalam rangka peningkatan pariwisata kota Purwokerto ini menggunakan metode kualitatif. BIORAMA hadir di Purwokerto sebagai wahana piknik alternatif untuk masyarakat Purwokerto yang merindukan tempat piknik tengah kota yang nyaman dan penuh keakraban dengan suasana bangunan gedung bersejarah di Purwokerto
Co-Authors Adnan Setyoko Endang Mahati Noor Wijayahadi Riri Irma Suryani Robert Hendra Yudianto Yora Nindita