Claim Missing Document
Check
Articles

Found 2 Documents
Search

Comprehensive Review of Sambiloto (Andrographis Paniculata) Rohama, Rohama; Dari, Kristina Wulan; Elieser, Michael; Kristina, Isha Desty; Puspita, Melinda Dian
PROMOTOR Vol. 7 No. 4 (2024): AGUSTUS
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v7i4.797

Abstract

This article provides a literature review of Sambiloto (Andrographis paniculata) covering key aspects such as raw material name, content and composition of raw material, active constituents/secondary metabolites, claimed benefits, empirical data, raw material standardization, preclinical studies, and toxicity tests. Data is sourced from various Indonesian journals and books published in the last five years to give an in-depth understanding of the benefits and potential of Sambiloto. The review results show that Sambiloto has significant health potential, but standardization and further tests are required to ensure its safety and efficacy.
Penetapan Kadar Flavonoid Ekstrak Daun Kalapapa (Vitex Pinnata L.) dengan Tingkatan Fraksi Elieser, Michael; Rohama, Rohama; Alawiyah, Tuti; Hakim, Ali Rakhman
El-Mujtama: Jurnal Pengabdian Masyarakat  Vol. 5 No. 1 (2025): El-Mujtama: Jurnal Pengabdian Masyarakat
Publisher : Intitut Agama Islam Nasional Laa Roiba Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/elmujtama.v5i1.5893

Abstract

The background to this research is that one of the plants that is often used by people in the interior of Central Kalimantan, specifically in the village of Tumbang Talaken, is the Kalapapa plant. The Dayak tribe community in the Tumbang Talaken area of Central Kalimantan uses Kalapapa leaves as a trusted medicinal plant and is used as a traditional medicine to heal wounds using the simple method of crushing the leaves and applying them directly to the surface of the injured skin. Kalapapa leaves contain flavonoids, alkaloids, saponins and tannins. In the context of wound healing, flavonoids have an important role in increasing the speed of wound healing. The aim of the research was to determine the levels of total flavonoid compounds in the distilled water fraction, ethyl acetate fraction, and n-hexane fraction of kalapapa leaf extract (Vitex Pinnata L.). The research method used was a descriptive method by looking at the results of qualitative data, namely a reaction test. color and quantitative data, namely using Uv-Vis spectrophotometry to see total flavonoid levels. The results of the qualitative analysis research showed that the color test identification of kalapapa leaf extract (Vitex Pinnata L.) was positive for containing flavonoids. The results of quantitative analysis using Uv-Vis spectrophotometry showed that the total flavonoid content with 96% ethanol extract was 43.95 QE/g, distilled water with a value of 42.14 QE/g, ethyl acetate with a value of 196.8 QE/g, and n -hexane with a value of 54.42 QE/g or 96% 4.39% ethanol extract, distilled water 4.21%, ethyl acetate 19.68%, and N-hexane 5.44%. The highest total flavonoid levels were found in the ethyl acetate fraction. The research conclusion is that kalapapa leaf extract at fraction levels contains flavonoid compounds with total flavonoid levels in the ethanol extract of 96%, distilled water fraction, ethyl acetate fraction and n-hexane fraction of 43.95 mg QE/g or 4.39%; 42.14 mg QE/g or 4.21%; 196.8 mg QE/g or 19.68%; and 54.42 mg QE/g or 5.44%.