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Sucralfate and Honey in Burn Wound Healing: An Article Review Wardhana, Aditya; Farhana, Nadya
Jurnal Plastik Rekonstruksi Vol. 11 No. 1 (2024): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25251/yjadqx70

Abstract

Introduction : Several studies stated that sucralfate and honey topically promote wound healing process. Sucralfate has been used for stomatitis, excoriation in perianal and peristomal, ulcers, and burn wounds. Honey as a food which is taken orally, is also used topically for several kind of wounds including burn wounds. However, there is no study reviewing sucralfate and honey in burn wounds. Method : Literature review was conducted from 1st until 6th of June 2022 using the terms of “honey”, “sucralfate”, “burns” and “wound healing”. Pubmed, Cohrane, Science Direct, Scopus, and Google Scholar were the online data bases we used. We identified eight studies, three trials evaluated the effects of sucralfate in burn wounds and five trials evaluated the effects of honey in burn wounds. Result : 3 Randomized Controlled Trials (RTCs) (n=170) about the effects of sucralfate and 5 RCTs (n=474) reported the effects of honey in burn wounds. Both Sucralfate and Honey group had similar wound healing duration around 18 days and had early sign of wound healing by day 7. Honey has faster complete wound healing compared to sucralfate by day 21. Honey has remarkable antimicrobial effect within one hour. No side effects were reported in both trials. Both honey and sucralfate reduce the necessity for skin grafting. Conclusion: Both sucralfate and honey have similar rapid re-epithelization in burn wounds, but honey has faster complete wound healing by day 21. Both has similar antimicrobial effect, no side effects, and reduce the necessity for skin grafting.
Analyzing The Efficacy and Outcome of Amniotic Membrane in Burn Care: A Systematic Review and Meta-Analysis Putri, Nandita Melati; Wardhana, Aditya; Sandora, Normalina; Syarif, Akhmad Noviandi; Farhana, Nadya; Oklia, Sheila
Jurnal Plastik Rekonstruksi Vol. 12 No. 1 (2025): (2025): Jurnal Plastik Rekonstruksi
Publisher : The Lingkar Studi Bedah Plastik Foundation and is affiliated with the Department of Plastic Surgery, Faculty of Medicine, Universitas Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v12i1.384

Abstract

Introduction: Managing burn injuries is a significant clinical challenge in promoting wound healing and minimizing complications. Advances like amniotic membrane as a biological dressing have been introduced to improve wound healing. This study analyzes the efficacy of amniotic membrane in burn care and its impact on wound healing outcomes.Methods: We conducted a systematic review in Pubmed, Cochrane, and ScienceDirect, using “Amnion”, “Burns”, and “Wound healing” as keywords. The inclusion criteria are studies assessing the application of amniotic membrane on burn wounds. The outcome measures were mean healing time, wound healing rate, incidence of wound infection, dressing renewal frequency, pain score, and LOS.Results: We identified eleven trials (n=971) ranging from the year 1989 to 2023, containing eight RCTs, and three NRCTs. The pooled RR showed statistically significant differences between amniotic membrane group and control group in mean healing time (RR -4.52 [95% CI; -6.93, -2.11]; p=0.0002), wound healing rate (RR 1.60 [95% CI; 1.09, 2.33]; p=0.02), incidence of wound infection (RR 0.48 [95% CI; 0.30, 0.77]; p=0.002), and dressing renewal frequency (RR -1.64 [95% CI; -2.48, -0.79]; p=0.0002).Conclusion: This meta-analysis indicates that amniotic membrane is advantageous as a biological dressing for burn patients.
Analisis Safety stock dan Reorder point Persediaan Produk Wheel-Grinding 4" di PT XYZ Farhana, Nadya; Wildan Firmayuda Yahya; Khamdi Mubarok
Jurnal Teknik Industri (JATRI) Vol. 3 No. 1 (2025): Jurnal Teknik Industri (JATRI)
Publisher : Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jatri.v3i1.2304

Abstract

Dalam industri manufaktur, pengelolaan persediaan menjadi aspek krusial yang mempengaruhi efisiensi produksi dan kepuasan pelanggan. Penelitian ini bertujuan untuk menganalisis safety stock dan menentukan reorder point untuk produk Wheel-Grinding guna memastikan kontinuitas produksi serta menghindari kehabisan stock yang dapat mengganggu operasional. Metode yang digunakan meliputi analisis permintaan historis, lead time, serta fluktuasi permintaan untuk menghitung tingkat safety stock yang optimal. Penentuan reorder point didasarkan pada kombinasi antara rata-rata penggunaan harian dan lead time, dengan penyesuaian berdasarkan tingkat safety stock yang telah dihitung. Hasil penelitian menunjukkan bahwa penerapan strategi safety stock dan reorder point yang tepat dapat meningkatkan efisiensi inventaris, mengurangi biaya penyimpanan, serta meminimalkan risiko kehabisan stok. Rekomendasi diberikan untuk implementasi kebijakan manajemen persediaan yang lebih baik, yang diharapkan dapat memberikan manfaat jangka panjang bagi perusahaan.
Sucralfate and Honey in Burn Wound Healing: An Article Review Wardhana, Aditya; Farhana, Nadya
Jurnal Plastik Rekonstruksi Vol. 11 No. 1 (2024): (2024) Jurnal Plastik Rekonstruksi
Publisher : The Lingkar Studi Bedah Plastik Foundation and is affiliated with the Department of Plastic Surgery, Faculty of Medicine, Universitas Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v11i1.371

Abstract

Introduction : Several studies stated that sucralfate and honey topically promote wound healing process. Sucralfate has been used for stomatitis, excoriation in perianal and peristomal, ulcers, and burn wounds. Honey as a food which is taken orally, is also used topically for several kind of wounds including burn wounds. However, there is no study reviewing sucralfate and honey in burn wounds.Method : Literature review was conducted from 1st until 6th of June 2022 using the terms of “honey”, “sucralfate”, “burns” and “wound healing”. Pubmed, Cohrane, Science Direct, Scopus, and Google Scholar were the online data bases we used. We identified eight studies, three trials evaluated the effects of sucralfate in burn wounds and five trials evaluated the effects of honey in burn wounds.Result : 3 Randomized Controlled Trials (RTCs) (n=170) about the effects of sucralfate and 5 RCTs (n=474) reported the effects of honey in burn wounds. Both Sucralfate and Honey group had similar wound healing duration around 18 days and had early sign of wound healing by day 7. Honey has faster complete wound healing compared to sucralfate by day 21. Honey has remarkable antimicrobial effect within one hour. No side effects were reported in both trials. Both honey and sucralfate reduce the necessity for skin grafting.Conclusion: Both sucralfate and honey have similar rapid re-epithelization in burn wounds, but honey has faster complete wound healing by day 21. Both has similar antimicrobial effect, no side effects, and reduce the necessity for skin grafting.
WOUND HEALING EFFICACY OF MOIST EXPOSED BURN OINTMENT (MEBO) AND SILVER SULFADIAZINE IN PARTIAL-THICKNESS BURNS: A SYSTEMATIC REVIEW Wardhana, Aditya; Farhana, Nadya
Jurnal Rekonstruksi dan Estetik Vol. 10 No. 2 (2025): Jurnal Rekonstruksi dan Estetik, December 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jre.v10i2.71980

Abstract

Highlights: Superior efficacy between MEBO and SSD in burn patients. Improved Clinical Outcomes of wound healing in burn patients. Natural, Plant-Based Alternative for burn patients.  Abstract: Introduction: Burn injuries are a common global health issue that often require prolonged wound care and can lead to complications such as infections, delayed healing, and surgical interventions. Silver sulfadiazine (SSD) has long been the standard topical treatment for partial-thickness burns, but concerns remain regarding delayed healing and potential side effects. Moist Exposed Burn Ointment (MEBO), a Chinese herbal-based topical agent containing sesame oil, beta-sitosterol, and berberine, has emerged as a potential alternative due to its anti-inflammatory, antimicrobial, and moisture-retaining properties. Method: This systematic review aimed to evaluate the efficacy of MEBO compared to SSD in partial-thickness burn wound healing. A comprehensive search of PubMed, Cochrane, and Science Direct using the terms “MEBO,” “SSD,” “Burns,” and “Wound healing” identified five trials conducted between 2000 and 2008. Result: The results consistently demonstrated that MEBO provided comparable or superior outcomes to SSD, including shorter wound healing time, reduced pain, absence of infection in wound swabs, minimal slough and crust formation, lower complication rates, and reduced need for surgical intervention. Conclusion: These findings suggest that MEBO is an effective and potentially preferable alternative to SSD for managing partial-thickness burn wounds.
Association Between Burn Excision Timing and Mortality in ICU Burn Patients: A Two-Year Retrospective Study Wardhana, Aditya; Farhana, Nadya; Leksono, Tiara Putri
Indonesian Journal of Anesthesiology and Reanimation Vol. 8 No. 1 (2026): Indonesian Journal of Anesthesiology and Reanimation (IJAR)
Publisher : Faculty of Medicine-Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijar.V8I12026.17-21

Abstract

Introduction: Severe burn injuries requiring Intensive Care Unit (ICU) admission are strongly associated with high mortality, particularly in patients with extensive total body surface area (TBSA) involvement, sepsis, and mechanical ventilation. Surgical excision is widely recommended as a component of burn care. However, its association with survival in critically ill burn patients remains debated, especially in low-resource settings. Objectives: To evaluate the association between burn excision timing and mortality outcomes in ICU-admitted burn patients. Methods: This retrospective cohort study was conducted at a burn unit referral hospital in Jakarta, Indonesia, from January 2023 to December 2024, and included 130 ICU-admitted burn patients. The intervention was burn excision, either early or delayed, compared with nonoperative management. Data were analyzed to determine mortality outcomes using chi-square testing, with p < 0.05 considered significant. Results: Among the included patients, most sustained flame burns involving more than 40% TBSA, with burn depth ranging from superficial dermal to full-thickness. Surgical burn excision was performed in 71.5% of cases. Mortality occurred in 44 patients in the early excision group, with early tangential excision conducted in 52.3% (68/130). Delayed excision, primarily due to late presentations and referral system delays, was performed in 25 patients with 10 deaths. Of the 35 patients who did not undergo excision, 32 died prior to surgical intervention. Statistical analysis revealed a significant association between excision timing and mortality outcome (p < 0.001), suggesting that surgical excision was associated with improved survival compared to non-operative care. Conclusion: These findings suggest that burn excision is associated with improved survival in critically ill populations. However, the retrospective design and survivor bias mean this association is not causal.