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All Journal Global Medical and Health Communication Jurnal Biogenerasi
Laila, Nazmy Noor
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Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Nursing Public Health Other

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Clinicopathological Characteristics of Breast Cancer at Cibabat Regional General Hospital in 2022–2023 Rachmawati, Meike; Acang, Nuzirwan; Purbaningsih, Wida; Robian, Rian; Nugraha, Adhi; Melati, Rina; Aryanti, Aryanti; Anugrah, Aninditya Putri; Laila, Nazmy Noor
Global Medical & Health Communication (GMHC) Vol 12, No 1 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i1.13462

Abstract

Breast cancer is the most common malignancy found in women throughout the world and is the fifth leading cause of cancer death in the world. Cibabat Regional General Hospital is one of the places for breast cancer examination and treatment in West Java. This study aims to determine the clinical and histopathological features at Cibabat Regional General Hospital. The method used in this research is descriptive-analytic with a total sampling technique using secondary data obtained from the medical records of Cibabat Regional General Hospital patients from 2022 to June 2023. The results show that most cases of breast cancer at Cibabat Regional General Hospital occur in those aged 45–54 (32.3%), left breast (52.1%), grade 3 (44.8%), histopathological type invasive carcinoma of no special type (75%), lymph node status unknown (88.5%), negative lymphovascular invasion (43.7%), and fat invasion status unknown (68.7%). The conclusion is that breast cancer cases at Cibabat Regional General Hospital mainly occur in patients of productive age with a high grade and predominantly in the left breast, with the most common type being invasive carcinoma of no particular type.
EKSTRAK ANTOSIANIN DARI BUAH STROBERI (FRAGARIA X ANANASSA) SEBAGAI PENGGANTI EOSIN PADA JARINGAN HATI TIKUS DENGAN PEWARNAAN HEMATOXYLIN-EOSIN Laila, Nazmy Noor; Mahmud, Dani; Oktari, Anita; Rukhiat, Diat
Jurnal Biogenerasi Vol. 10 No. 2 (2025): Volume 10 no 2 periode februari - september 2025 ( continues)
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v10i2.6022

Abstract

Tissue staining is necessary to show the structure and morphology of the tissue, namely Hematoxylin Eosin (H&E) staining. However, eosin is carcinogenic when used in the long term. The aim of this research is expected to develop the use of natural materials as an alternative for Hematoxylin-Eosin histological staining. One of the color pigments that can be obtained from natural materials is the anthocyanin pigment found in strawberries. The anthocyanin extract from strawberries, which is acidic like eosin, will bind to positively charged molecules in the basic cytoplasm. The design of this study uses a simple experimental design (Posttest Only Design). Based on the Mann Whitney U test, a significant result was obtained with a value of sig.<.001 <0.05, indicating a significant difference in the results between the preparations stained with hematoxylin and eosin and those stained with hematoxylin and anthocyanin extract. Thus, it can be concluded that statistically, staining with hematoxylin and anthocyanin extract cannot be used as a substitute for hematoxylin eosin. Nevertheless, the results of staining the preparations using hematoxylin and anthocyanin extract still produce color in the cytoplasm, and are sufficiently contrasting to distinguish between the color of the cytoplasm and the color of the nucleus.
Co-Authors Adhi Nugraha Anita Oktari, Anita Anugrah, Aninditya Putri Aryanti Aryanti Mahmud, Dani Meike Rachmawati Melati, Rina Nuzirwan Acang Robian, Rian Rukhiat, Diat Wida Purbaningsih