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Hubungan Kemampuan Menciptakan Gelap Terang Dengan Kemampuan Menggambar Kubus Dalam Gambar Bentuk Pada Siswa Kelas Viii Smp Muhammadiyah Medan Hasan, Nur Aini; Sugito, Sugito
Visual Heritage: Jurnal Kreasi Seni dan Budaya Vol 6, No 3 (2024): Visual Heritage: Jurnal Kreasi Seni Dan Budaya
Publisher : Universitas Indraprasta PGRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30998/vh.v6i3.10777

Abstract

Penelitian ini bertujuan untuk membuktikan apakah ada hubungan antara kemampuan menciptakan gelap terang dengan kemampuan menggambar kubus yang signifikan dan seberapa besarkah pengaruh dari penggunaan teknik dusel terhadap kemampuan menggambar kubus serta hubungan antar faktor yang menjadi penghambat dan pendukung dalam menciptakan gelap terang dengan kemampuan menggambar kubus pada kelas VIII Terpadu 4 SMP Muhammadiyah 1 Medan, Metode yang digunakan pada penelitian ini merupakan Korelasional (Correlational Research) penelitian ini melibatkan satu kelas dan memakai 2 tes dari hasil penelitian diperoleh kenaikan yang signifikan dari hasil Postest dibandingkan dengan hasil Pretest. penggunaan Teknik Dusel mencapai keberhasilan 73% dan penggunaan teknik konvensional sebesar 72% hasil perhitungan (uji linerasi) di peroleh bahwa penelitian ini menggunakan tes menggambar kubus menunjukkan kemajuan pada gambar siswa kelas VII Terpadu 4 pada SMP Muhammadiyah sehingga Ho diterima Ha ditolak, artinya terdapat hubungan signifikan positif antara penilaian prestasi kerja dengan pengembangan individu dapat disimpulkan bahwa terdapat pengaruh yang signifikan dari penggunaan teknik dusel terhadap kemampuan menggambar kubus pada siswa kela VIII Terpadu 4 SMP Muhammadiyah 1 Medan.
Genetic Diversity and Multiplicity of Plasmodium falciparum Infection in Southeast Asia: New Insights from a Systematic Review Praswitasari, Rengganis; Husada, Dominicus; Hasan, Nur Aini; Adnyana, I Made Dwi Mertha
Journal of Multidisciplinary Applied Natural Science Articles in Press
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.357

Abstract

Plasmodium falciparum caused four million new malaria cases in Southeast Asia in 2023, with heterogeneous transmission patterns and the development of artemisinin resistance. The merozoite surface protein genes (msp-1 and msp-2) serve as genetic markers for analyzing the parasite population structure and multiplicity of infection (MOI). However, a comprehensive synthesis of regional data is limited. This study aimed to determine the genetic diversity and MOI of P. falciparum in Southeast Asia. This systematic review was guided by PRISMA guidelines with searches in the Scopus, PubMed, ProQuest, and Google Scholar databases (2014–2024). The inclusion criterion was observational studies, analyzing the genetic diversity of P. falciparum via msp-1 and msp-2 markers in Southeast Asia. The extracted data included the frequency of msp-1 and msp-2 family alleles, the prevalence of polyclonal infections, and the mean MOI value. Quality assessment was performed via the joanna briggs institute critical appraisal tools with narrative synthesis following the synthesis without meta-analysis (SWiM) guidelines. Fifteen studies; Indonesia (40%), Thailand (26.67%), Myanmar (20%), Vietnam and Malaysia (6.66%) with 1,830 samples successfully genotyped from 2,130 collected samples. The MAD20 (msp-1) allele dominated most locations, with frequencies of up to 100% in Lampung. The distribution of msp-2 alleles showed geographical variation, with FC27 dominating in Papua (96.2%) and 3D7/IC in Vietnam (97.0%). The prevalence of polyclonal infection ranged from 0-84.6%, with MOI values ranging from 1.0-2.93. The hyperendemic areas presented high MOIs (>2.0), whereas the hypoendemic areas presented MOIs close to 1.0, confirming a positive correlation with malaria transmission intensity. The P. falciparum population in Southeast Asia shows high genetic diversity, with geographically variable allele distribution patterns, and MOI values are correlated with malaria endemicity levels. These findings support the need for regional molecular surveillance and a polyvalent approach to the development of msp-based vaccines.