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All Journal Conservative Dentistry Journal
Agustin Wahjuningrum, Dian
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Dentistry

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Pulp tissue regeneration in the treatment of immature premolars accompanied by infection: A case report Gabriella Djuanda, Anastasia; Dianti, Eska; Auzan Fepiosandi, Radixtio; Lazuardi Ramadhan, Daniyal; Agustin Wahjuningrum, Dian; Setyabudi
Conservative Dentistry Journal Vol. 12 No. 2 (2022): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v12i2.2022.95-99

Abstract

Background: Young permanent teeth are one of the challenges in performing endodontic treatment. Revascularization is a good yet simple treatment option for pulp tissue regeneration to stimulate periapical lesion healing, continue root growth and restore pulp tissue function. Purpose: This case report describes management of pulp tissue regeneration in teeth with infection. Case: Female, 16 years old, came complaining of pain in the left lower back tooth accompanied by recurrent swelling. Radiograph showed an open apex with apical lesion on tooth 35. The diagnosis was pulpal necrosis accompanied by a chronic apical abscess. Case management: The treatment plan was revascularization and direct composite restoration. After accessing the cavity, the teeth were prepared, irrigated, and medicated with TAP, which was repeated for 2 visits. On the next visit, after the root canal was cleaned, over instrumentation was performed for bleeding and Collaplug was placed over the blood clot, covered with MTA, and composite resin for coronal sealing. Follow up was carried out for up to 9 months and was asymptomatic. Radiographs show healing of the lesion accompanied by closure of the root canal. Conclusion: Regenerative endodontics has been shown the successful in stimulating root canal closure to treat immature teeth
Human dental pulp mesenchymal stem cells regenerative potential Fadiyan Amriel, Menza; Priyo Prasetyo, Eric; Auzan Fepiosandi, Radixtio; Agustin Wahjuningrum, Dian; Suardita, Ketut; Zora, Zofia; Natan, Daniel; Bin Zainal Abidin, Imran; Ohara, Masaru
Conservative Dentistry Journal Vol. 15 No. 1 (2025): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i1.2025.27-32

Abstract

Background: Stem cells can be divided into mono-potent, oligopotent, multipotent, pluripotent, and totipotent. Dental and oral stem cells are stem cells found in the teeth and mouth that has the potential to develop into various cell types. The rapid development of regenerative dentistry has resulted in the exploration of stem cells, including dental pulp mesenchymal stem cells. Mesenchymal stem cells, have important regenerative potential in repairing dental and surrounding tissues. One of dental stem cells source that have been discovered is dental pulp mesenchymal stem cells. Purpose: This article aims to review the regenerative potential of human dental pulp mesenchymal stem cells (HDPMSCs). Review: HDPMSCs are potential for regenerative dentistry, including regenerative endodontics due to their multipotency, ease of collection, and ability to support tissue repair, immunomodulation, and regeneration across dental, orthopedic, neurological, and cardiovascular applications. Conclusion: The regenerative potentials of HDPMSCs on various treatments are vastly explored by many studies.
Co-Authors Bin Zainal Abidin, Imran Dianti, Eska Fadiyan Amriel, Menza Gabriella Djuanda, Anastasia Ketut Suardita, Ketut Lazuardi Ramadhan, Daniyal Natan, Daniel Ohara, Masaru Priyo Prasetyo, Eric Radixtio Auzan Fepiosandi Setyabudi Zora, Zofia