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Elfia, Linda
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Biochemistry, Genetics & Molecular Biology Public Health

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Uji Perbandingan Aktivitas Antibakteri Ekstrak Kulit Buah Kandis (Garcinia Xanthochymus) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus Rahmat Yuza, Ibnu; Abeiasa, M. Saka; Elfia, Linda
Jurnal Medisains Kesehatan Vol. 4 No. 2 (2023): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v4i2.205

Abstract

Penelitian ini bertujuan untuk mengetahui dan melihat perbandingan aktivitas daya hambat ekstrak kulit buah kandis (Garcinia xanthochymus) pada fraksietanol dan fraksi air terhadap bakteri Staphylococcus aureus. Metode yang digunakan untuk mengetahui potensi ekstrak dalam menghambat pertumbuhan bakteri ialah menggunakan metode cakram kertas yang berupa zona inhibisi yang membentuk disekitar cakram kertas. Berdasarkan dari hasil skrining fitokimia dari tanaman yang digunakan diketahui bahwa tanaman kulit buah kandis (Garcinia xanthochymus) memiliki zat aktif berupa saponin, flavanoid, alkaloid. Hasil penelitian peningkatan dosis pada ekstrak kulit buah kandis (Garcinia xanthochymus) fraksi etanol konsentrasi 5% terhadap konsentrasi 10% ada perbedaan, sedangkan konsentrasi 5% terhadap konsentrasi 15% dan konsentrasi 10% terhadap 15% itu tidak ada perbedaan. Hasil penelitian peningkatan dosis pada ekstrak kulit buah kandis (Garcinia xanthochymus) fraksi air konsentrasi 5% terhadap konsentrasi 10% dan terhadap konsentrasi 15% tidak memiliki perbedaan. Maka dapat disimpulkan ekstrak kulit buah kandis fraksi etanol lebih efektif dalam menghambat pertumbuhan aktifitas bakteri Stapylococcus aureus dibandingkan dengan ekstrak kulit buah kandis fraksi air. Aktivitas anti bakteri terhadap bakteri Staphylococcus aureus terbaik ditunjukkan oleh fraksi etanol ekstrak kulit buah kandis (Garcinia xanthochymus) konsentrasi 5% terhadap 10%, yaitu dengan nilai signifikansi 0.021.
Pengaruh Pemberian Ekstrak Pacar Kuku (Lawsonia inermis L) Untuk Penyembuhan Luka Bakar Pada Mencit Putih Elfia, Linda; Abeiasa, M Saka; Humaira, Vilma; Rahmi, Fatihatur
Jurnal Medisains Kesehatan Vol. 3 No. 2 (2022): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v3i2.251

Abstract

Burns are injuries caused by direct contact or exposure of the body to sources of heat, chemicals, electricity and radiation. Burns not only cause damage to the skin but can also affect the body's system. Therefore, burns require special attention in handling. Lawsonia inermis L. is a plant that contains compounds that play a role in wound healing such as flavonoids, saponins and tannins. This study aims to determine whether there is an effect of henna leaf extract on healing burns. Nail henna leaf extract was made by maceration using 96% ethanol as solvent. This study used male mice as test animals which were divided into 5 groups, the positive control group was not given treatment, the negative control group was given vaseline flavum and 3 groups were given henna leaf extract with concentrations of 20%, 40% and 60%. Burns were made by using preheated solder for 5 minutes. The intervention was carried out once a day. The results of the statistical analysis of the One Way ANOVA test showed that the concentration of fast burn healing was 40%.
Uji Aktifitas Daya Hambat Ekstrak Daun Jambu Biji (Psidium Guajava) Terhadap Pertumbuhan Bakteri Streptococcus Mutans Ramadhan, Willy Syahrina; Elfia, Linda; Iisniawati, Iisniawati
Jurnal Medisains Kesehatan Vol. 6 No. 1 (2025): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v6i1.523

Abstract

Dental caries is a common oral health problem caused by Streptococcus mutans, a bacterium that ferments carbohydrates into acid and damages tooth enamel. The high prevalence of dental caries in Indonesia highlights the need for natural antibacterial alternatives. Guava (Psidium guajava) leaf contains flavonoids, tannins, and saponins that have antibacterial potential. This study aims to determine the inhibitory effect of ethanol extract of guava leaves on Streptococcus mutans at concentrations of 1.25%, 2.5%, and 5%. The research used a laboratory experimental method with a Completely Randomized Design (CRD). Extraction was performed using maceration with 96% ethanol, while antibacterial testing used the disc diffusion method. The results showed inhibition zones at all concentrations, with the strongest inhibition at 5%. These findings indicate that guava leaf extract may serve as a natural antibacterial agent for preventing dental caries.
Co-Authors Abeiasa, Muhammad Saka Iisniawati, Iisniawati Rahmat Yuza, Ibnu Rahmi, Fatihatur Ramadhan, Willy Syahrina Vilma Humaira