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All Journal Journal of Health and Dental Sciences International Journal of Health and Pharmaceutical (IJHP)
Soraya Tanjung, Dian
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Dentistry Nursing Public Health

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Effect of Moringa Flower Extract (Moringa Oleifera) on Collagenization and Histopathology of Skin Tissue in the Healing of Dermapen Scars in Obese Male Wistar White Rats Soraya Tanjung, Dian; Kurniawati, Rachmi; Adi Mylano, Tri
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 2 (2024): May 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i2.318

Abstract

Injury can be accidental, intentional, or disease-related. Moringa leaves may help heal wounds. The research aims to test and assess the effects of Moringa oleifera flower extract on dermapen wound healing collagenization in male Wistar strain white rats, an obese model, and their histological findings—quantitative True Experimental Study with Post-Test Only Control Group Design. Twenty-four male Wistar white rats (Rattus norvegicus) were sampled. Accumulation of Test Animals, Moringa Flower Extract Preparation, Phytochemical Screening / Secondary Metabolite Test, Treatment Process (200, 400, and mg/kgBW of Moringa flower extract), Wound Observation, Histopathological Skin Preparations, and Histopathological Examination of Preparations were the research procedures. Window data was analyzed using SPSS 25.0 and One Way ANOVA with a 95% confidence level (p < 0.05). The Post Hoc Test with LSD was used for further analysis. The research results found Moringa flower extract at 200mg/Kg BW, 400mg/KgBW, and 600mg/KgBW could expedite wound healing and improve collagen density in obese mice's dermapen wounds. The 600mg dose was most beneficial. Research conclusions: Moringa flower extract aids dermapen wound healing, collagenization, and obesity weight loss, according to a study.
THE DIFFERENCES IN THE EFFECTS OF PROPOLIS, SODIUM HYPOCHLORITE, AND EDTA AS AN IRRIGANT SOLUTIONS ON THE MICROHARDNESS OF ROOT CANAL DENTIN: IN-VITRO STUDY Florencia Farrent Br S. Pandia, Ellen; Soraya Tanjung, Dian; Reni Purba, Member
Journal of Health and Dental Sciences Vol. 4 No. 3 (2025): Journal of Health and Dental Sciences
Publisher : Fakultas Kedokteran Gigi Unjani

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Abstract

Sodium hypochlorite (NaOCl) and EDTA are commonly used irrigants due to their antimicrobial properties and ability to dissolve both organic and inorganic components. However, the use of these chemicals at varying concentrations and durations can affect the physical and chemical properties of root canal dentin. Recently, propolis has gained attention as an alternative irrigant because it shows similar potential to conventional irrigants. The aim of this study is to examine whether there are differences in the effects of propolis extract, NaOCl, and EDTA on the microhardness of root canal dentin. This study utilized 24 single-rooted premolar teeth. The crowns were removed, and the roots were longitudinally split into two halves. Samples were randomly divided into six groups (n=8), each immersed in 8% propolis, 20% propolis, 30% propolis, 2.5% NaOCl, 5% NaOCl, and 17% EDTA. The microhardness of root canal dentin was measured using a Vickers Hardness Tester before and after immersion. Data were analyzed using One Way ANOVA. The results showed that 8% propolis had the smallest decrease in microhardness among all treatment groups, with an average difference in initial and final microhardness of 3.68, followed by 20% propolis, 2.5% NaOCl, 5% NaOCl, 30% propolis, and 17% EDTA. The conclusion of this study is that there are significant differences (p<0.05) among the treatment groups regarding the microhardness of root canal dentin. Extracts of 8% and 20% propolis can be used as alternative irrigants. DOI : 10.54052/jhds.v4n3.p255-264
Co-Authors Adi Mylano, Tri Florencia Farrent Br S. Pandia, Ellen Rachmi Kurniawati, Rachmi Reni Purba, Member