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All Journal Dental Journal (Majalah Kedokteran Gigi) Indonesian Journal of Dental Medicine Community Empowerment
Leo, Leviena Merlynike
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Arts Humanities Dentistry Education Public Health Social Sciences

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The Combination of Ultraviolet-B and Vitamin K2 Exposure Effect on Fibroblast-like cell Number in Wistar Rats Nelwan, Sindy Cornelia; Tedjosasongko, Udijanto; Dharmawan, Devi; Leo, Leviena Merlynike; Ardiana, Hana Ai; Rahmawati, Siti
Indonesian Journal of Dental Medicine Vol. 6 No. 1 (2023): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v6i1.2023.19-23

Abstract

Background: Vitamin D deficiency in children is one of the problems most often discussed and received attention from around the world today, especially during the Corona virus disease-19 (Covid-19) pandemic. Vitamin D3 increases the production of vitamin K2 protein and activates a protein involved in bone metabolism. Vitamin K2 increases bone formation by stimulating osteoblast differentiation, regulating mineralization of the extracellular matrix, regulating bone marker gene expression, and inhibiting osteoclastogenesis. Purpose: to analyzed the effect of sun exposure, Ultraviolet-B (UV-B) and vitamin K2 supplementation on fibroblast-like cell as bone formation marker in Wistar rats (Rattus novergicus). Methods: twenty-four samples divided into 4 groups namely control group, UV-B group, vitamin K2 group, combination of UV-B and vitamin K2 group. After 21 days, extraction of lower incisors was done to examine fibroblast-like cell number "‹"‹after treatment. After being decalcified, specimens underwent histological evaluation using Haemotoxylin and Eosin staining to observe the fibroblast-like cell number. Result: Data analysis of fibroblast like cells number expression using one way analysis of variance (ANOVA) test showed a significant difference between sample groups (p<0.05). Conclusion: The combination of UV-B exposure and vitamin K2 administration group increased of fibroblast-like cells in Wistar rats (R. novergicus).
Improving dental emergency literacy for preschool teachers and parents Nelwan, Sindy Cornelia; Puteri, Mega Moeharyono; Wicaksono, Dimas Prasetianto; Leo, Leviena Merlynike; Kumalasari, Agnes Herlina; Prayogo, Rosiana Dewi; Nisak, Rosyida Ainun; Karuniadewi, Anak Agung Sagung Dyah; Putri, Sofia Tandya; Ardani, Pradhika; Nasia, Avina Anin
Community Empowerment Vol 10 No 4 (2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.12528

Abstract

Medical emergencies can occur in dentistry, including trauma to primary teeth. The global prevalence of dental trauma in children is 10-15%. Trauma to primary teeth can have severe medical, aesthetic, and psychological impacts. Parents and teachers at school are among the most important actors in providing emergency dental care for children. Therefore, providing information that increases parents’ and teachers’ knowledge about pediatric dental emergencies must be done so that appropriate management can be carried out. The method used was training on managing pediatric dental emergencies for parents and teachers at Whiz Kids Playschool Kindergarten. The evaluation showed increased participants’ knowledge before (Range = 10–80, Mean = 47.2) and after (Range = 70–100, Mean = 87.0) the training. Thus, this training successfully increased parents’ and teachers’ knowledge of managing pediatric dental emergencies.
Cell phone radiation effect on osteocalcin and bone alkaline phosphatase Nelwan, Sindy Cornelia; Tedjosasongko, Udijanto; Puteri, Mega Moeharyono; Wicaksono, Dimas Prasetianto; Leo, Leviena Merlynike; Ardiana, Hana Ai; Rahmawati, Siti; Nowwarote, Nunthawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 1 (2024): March
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i1.p28-32

Abstract

Background: Electromagnetic fields are forces associated with moving electric charges and have electrical, magnetic components and contain electromagnetic energy, one of which is radio frequency (RF) energy which is commonly used in telecommunications. Cell phones are one of the RF electromagnetic radiation devices that can emit 90-2450 MHz waves and are often placed near the head. The human body works like an electromagnetic field in that each cell has its own electrical circuit characteristics. As the number of electromagnetic radiation devices in the environment increases, the electromagnetic balance in the human body may be disturbed by the magnetic waves produced by cell phones. Electromagnetic radiation is known to have the ability to induce oxidative stress, which is characterized by the accumulation of reactive oxygen species (ROS) in tissues. The accumulation of ROS in the body leads to osteoblast cell death. Osteoblasts are needed for mineralization of the extracellular matrix during bone growth. Therefore, bone growth is not optimal and can caused malocclusion. Purpose: This study aims to evaluate the relationship between electromagnetic radiation and osteocalcin and bone alkaline phosphatase (BALP) serum levels. Methods: Experimental laboratory research with a pre- and post-control group design approach was carried out on 12 Rattus norvegicus Wistar strain. Osteocalcin and BALP serum levels were calculated before and after treatment. This study used the t-test as a comparative study (p<0.05). Results: There are significant differences in osteocalcin and BALP values between the treatment groups before and after treatment. Conclusion: Cell phone radiations (electromagnetic field exposure) reduce osteocalcin and BALP serum levels.
Co-Authors Ardani, Pradhika Ardiana, Hana Ai Avina Anin Nasia, Avina Anin Dharmawan, Devi Dimas Prasetianto Wicaksono Karuniadewi, Anak Agung Sagung Dyah Kumalasari, Agnes Herlina Mega Moeharyono Puteri Nelwan, Sindy Cornelia Nisak, Rosyida Ainun Nowwarote, Nunthawan Prayogo, Rosiana Dewi Putri, Sofia Tandya Rahmawati, Siti Irma Siti Rahmawati Udijanto Tedjosasongko