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., Nofriyanti
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Formulasi Losion Minyak Sereh Wangi (Citronella Oil) Sebagai Anti Kutu Kepala (Pediculisid) Agistia, Nesa; Hafizah, Afrah; Susanti, Emma; ., Nofriyanti
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 3 No 1 (2024): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v3i1.1269

Abstract

Fleas (Pediculus humanus capitis) is one of the little parasites that live by sucking blood from a human head. While sucking blood, the flea secretes a secretion that irritate the skin tissues it causes a massive itch. Fleas can be treated by chemical drugs like 1 % permethrin, but it did have side effect of itching, rusting, swelling in the skin and massive burning sensation. Citronella oil (Cymbopogon nardus) have a chemical content which are insecticidal among them is citronellal which can be used as a natural pediculosid. This research aims to formulate lotion preparations that are stable and effective as anti-fleas and increase the time of death of fleas compared to permethrin. The concentrations of citronella oil used for F1, F2 and F3 were 5%; 7.5%; and 10%. The three formulas were evaluated including organoleptic examination, homogeneity, pH, emulsion type, dispersibility, viscosity, skin irritation, cycling test, and anti-lice activity test. Data analysis used the Kruskal Wallis statistical test. Based on the results of the evaluation of the preparations, it was found that the organoleptic examination of the preparation of lotions FI, FII, FIII had a consistency of thick to liquid form, white to pale yellow, had a distinctive smell of citronella oil, FI test pH = 7.31-6.51, FII = 7 03-6,38 and FIII = 6,98-6,35, FI spread ability test = 6,15-7,75 cm, FII = 6,55-8,25 cm and FIII = 8,55-10,05 cm, emulsion type test FI, FII, FIII have emulsion type M / A, FI viscosity test = 2956-3107 cPs, FII = 2360-2677 cPs, FIII = 764-980 cPs, homogeneity test on FI, FII, FIII homogeneous, freeze and thaw test on FI, FII is stable while FIII is unstable, skin irritation test on FI, FII, FIII is not irritation, FI anti-flea activity test = 122-167 seconds, FII = 117-128 seconds, FIII = 69-90 seconds.
Formulasi dan Uji Aktivitas Serum Spray Gel Minyak Adas (Feoniculum Vulgare Mill.) terhadap Bakteri Propionibacterium Acnes Agistia, Nesa; ., Nofriyanti; Pratiwi, Erniza; Azizah, Mifza
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2449

Abstract

Acne is a prevalent dermatological condition primarily caused by the bacterium Propionibacterium acnes. Antibiotics are used in acne therapy; however, increasing bacterial resistance has been reported in numerous studies. Fennel (Foeniculum vulgare Mill.) essential oil is known to exhibit antibacterial properties, mainly due to its active constituents, anethole and fenchone. This study aimed to develop a pharmaceutically stable serum spray gel formulation containing fennel essential oil and to evaluate its anti-acne activity. Fennel essential oil was formulated into serum spray gel preparations at concentrations of 10%, 15%, and 20%. The formulations were evaluated for organoleptic characteristics, pH, homogeneity, viscosity, flow behavior, adhesiveness, physical stability, spray pattern, and antibacterial activity.The results demonstrated that all serum spray gel formulations exhibited good physical stability, as indicated by acceptable organoleptic properties, homogeneity, pH values, viscosity, flow behavior, adhesiveness, stability, and spray patterns. One-way analysis of variance (ANOVA) revealed a statistically significant difference (p < 0.05) among the formulations in terms of antibacterial activity, as measured by the diameter of the inhibition zones. Post hoc Tukey analysis showed that the 10% fennel essential oil formulation exhibited the highest antibacterial activity, with an inhibition zone diameter of 23.6 mm, which was classified as strong antibacterial activity.
Co-Authors Agistia, Nesa Azizah, Mifza Hafizah, Afrah Pratiwi, Erniza Ronapadua Musyirna Rahmah Nasution Sahara dan Emma Susanti