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Formulasi dan Uji Aktivitas Serum Spray Gel Minyak Adas (Feoniculum Vulgare Mill.) terhadap Bakteri Propionibacterium Acnes Agistia, Nesa; ., Nofriyanti; Pratiwi, Erniza; Azizah, Mifza
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2449

Abstract

Acne is a prevalent dermatological condition primarily caused by the bacterium Propionibacterium acnes. Antibiotics are used in acne therapy; however, increasing bacterial resistance has been reported in numerous studies. Fennel (Foeniculum vulgare Mill.) essential oil is known to exhibit antibacterial properties, mainly due to its active constituents, anethole and fenchone. This study aimed to develop a pharmaceutically stable serum spray gel formulation containing fennel essential oil and to evaluate its anti-acne activity. Fennel essential oil was formulated into serum spray gel preparations at concentrations of 10%, 15%, and 20%. The formulations were evaluated for organoleptic characteristics, pH, homogeneity, viscosity, flow behavior, adhesiveness, physical stability, spray pattern, and antibacterial activity.The results demonstrated that all serum spray gel formulations exhibited good physical stability, as indicated by acceptable organoleptic properties, homogeneity, pH values, viscosity, flow behavior, adhesiveness, stability, and spray patterns. One-way analysis of variance (ANOVA) revealed a statistically significant difference (p < 0.05) among the formulations in terms of antibacterial activity, as measured by the diameter of the inhibition zones. Post hoc Tukey analysis showed that the 10% fennel essential oil formulation exhibited the highest antibacterial activity, with an inhibition zone diameter of 23.6 mm, which was classified as strong antibacterial activity.
Gambaran Tingkat Pengetahuan Masyarakat tentang Swamedikasi Obat Apotek di Kabupaten Sleman dan Yogyakarta Marlian, Ririn Irma; Shalahuddin Al Madury; Sual, Kezia Charania Vinly Marcya; Joangga, Ilham; Alvita, Stefani Nuri; Rahmawati, Nisa; Azizah, Mifza; Amalia, Siska
Jurnal Indonesia Sehat Vol. 4 No. 3 (2025): JURINSE: Desember 2025
Publisher : SAMODRA ILMU: Lembaga Penelitian, Penerbitan, dan Jurnal Ilmiah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58353/jurinse.v4i3.273

Abstract

Background: Self-medication is the use of drugs by individuals to treat perceived or self-diagnosed health conditions without consulting healthcare professionals. While self-medication can offer benefits such as faster relief of symptoms without the need to visit healthcare facilities, improper practices in obtaining, using, storing, and disposing of medications remain common in the community. Objective: This study aims to describe the public’s level of knowledge regarding self-medication.  The findings help to strengthen health behavior theories that emphasize the role of knowledge as a key determinant in responsible self-medication practices. Methods: A descriptive research design was employed using an observational method through a questionnaire consisting of 20 statements. A total of 90 respondents participated in the study with randomized sampling. Results: The majority of respondents were aged 18–25 years (28.88%), female (64.44%), worked as housewives (25.55%), and had completed senior high school (63.33%). The level of knowledge about self-medication was mostly in the "low" category (43.33%). The highest average correct response was in the category of knowledge related to how to obtain self-medication drugs, with a score of 74.07%. Conclusion: The public's knowledge level about self-medication is generally moderate. There is a need for enhanced education and outreach programs to promote proper self-medication practices and reduce the risk of drug misuse.