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All Journal Jurnal Serambi Biologi
Rahmawati, Atika Ayu
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Literature Article Review: Gambir Plant (Uncaria gambir Roxb) as Antioxidant Producer Rahmawati, Atika Ayu; Yuniarti, Elsa
Jurnal Serambi Biologi Vol. 9 No. 1 (2024): Jurnal Serambi Biologi
Publisher : Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/srmb.v9i1.316

Abstract

Abstract Gambier (Uncaria gambir Robx) is one of the typical spices of West Sumatra which contains chemical compounds and bioactive components that have the potential to be used as raw materials for medicines in the pharmaceutical industry. The bioactivity of this gambier plant can stimulate and enhance the immune system. The purpose of study is to present a summary of the literature review to gather overall information about the gambier plant as an antioxidant producer. The method used in literature review article research is the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) approach. Using literature in the form of Publish or Perrish, (2010-2023). Based on the results of the literature review, 12 journals were obtained. Based on the results of a literature review article showing various properties found in gambier plants due to suspected chemical compounds including phenolics and flavonoids such as quercetin and catechin, which have potential bioactivity, namely having antioxidant and anti-inflammatory properties. From several research results, the gambier plant part is proven to have many pharmacological properties that can increase the productivity of drugs with natural ingredients. Key words : Gambir, Antioxidant, Bioactive Compound, Literature Review
Genetic Variation Analysis of the E6 HPV 16 Gene Using RFLP In Silico Annisa, Silvy; Rahmawati, Atika Ayu; Nadira; Khairani, Fidia Aura; Achyar, Afifatul
Jurnal Serambi Biologi Vol. 9 No. 1 (2024): Jurnal Serambi Biologi
Publisher : Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/srmb.v9i1.331

Abstract

Cervical cancer is cancer that attacks epithelial cells or the outer surface layer of the cervix. This cancer is most commonly caused by the high risk type of Human Papillomavirus. The RFLP method uses restriction enzymes to cut certain nucleotide sequences at specific positions that produce fragments of different lengths. The purpose of this study was to determine the polymorphism that occurs in the E6 gene of the HPV 16 virus. This research was conducted using RFLP in silico. Virtual descriptive methods are used to analyze data and collect information about the object of study. The restriction enzyme HpaII was used in this study. The results showed that there were two alleles (A1 and A2) out of a total of 15 sequences of the E6 HPV 16 gene in Popset 636528409 indicating that there was a genetic variation in the gene.
Co-Authors Achyar, Afifatul Annisa, Silvy Elsa Yuniarti Khairani, Fidia Aura Nadira