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All Journal Abdi Geomedisains Usadha Journal of Pharmacy
Sikanaa, Arinaa Manaa
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Earth & Planetary Sciences Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing

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Pengaruh Edukasi DAGUSIBU Obat terhadap Peningkatan Pengetahuan Kader PKK di Dusun Sanggrahan Desa Potronayan, Kecamatan Nogosari, Boyolali Karuniawati, Hidayah; Salsabila, Aulia Shafa; Sikanaa, Arinaa Manaa; Saskia, Adinda Tri Prabandari; Dewi, Meilenia Shinta Kusuma; Hanjani, Wildanoor Sekar; Muhayaroh, Miftah
Abdi Geomedisains Vol. 5, No. 1, June 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/abdigeomedisains.v5i1.1778

Abstract

DAGUSIBU (DApatkan, GUnakan, SImpan, BUang) is a program initiated by pharmacists to improve the general community so that people can know how to get medicine, store, and dispose of drugs that are no longer used properly. The inappropriate use of drugs by the community is because of the lack of knowledge and information about the correct use of drugs. Therefore, efforts are needed to increase public knowledge through educational activities. This activity was conducted using the socialization method through counseling and distributing brochures containing knowledge about DAGUSIBU. Respondents filled out the questionnaire twice, namely before and after counseling. Data were analyzed descriptively and analytically with the Wilcoxon test because the data were not normally distributed. A total of 65 participants participated in this activity, with the age of the participants ranging from 21-60 years, the majority of education levels were Senior High School (SMA), as much as 45%, and 68% were homemakers. Statistical results showed a significant increase in knowledge between before and after counseling (p-value<0.05). So it can be concluded that counseling can increase appropriate knowledge about obtaining, using, storing, and disposing of drugs.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI JINTAN HITAM (Nigella sativa L.) TERHADAP BAKTERI Klebsiella pneumoniae DAN Methicillin Resistant Staphylococcus aureus (MRSA) SERTA BIOAUTOGRAFINYA Sikanaa, Arinaa Manaa; Muflihah, Cita Hanif
Usadha Journal of Pharmacy Vol. 4 No. 3 (2025): Agustus
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v4i3.538

Abstract

Jintan hitam (Nigella sativa L.) adalah salah satu tanaman yang berfungsi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak dan fraksi jintan hitam terhadap bakteri Klebsiella pneumoniae dan Methicillin Resistant Staphylococcus aureus (MRSA). Biji jintan hitam diekstraksi dengan etanol 96% hingga diperoleh ekstrak cair. Ekstrak difraksinasi menggunakan pelarut n-heksan, etil asetat, dan air. Uji aktivitas antibakteri dilakukan dengan metode disc diffusion dengan parameter diameter zona hambat. Kandungan senyawa diuji dengan kromatografi lapis tipis (KLT) dengan fase diam silika gel GF 254 dan fase gerak metanol: sikloheksana: diklorometana (6:20:74). Uji bioautografi dilakukan dengan metode bioautografi kontak. Hasil penelitian menunjukkan ekstrak Nigella sativa L. memiliki aktivitas antibakteri paling baik terhadap bakteri Klebsiella pneumoniae dan Methicillin Resistant Staphylococcus aureus (MRSA) adalah ekstrak dengan konsentrasi 80% v/v (10 µL/disk) dengan diameter zona hambat berturut-turut adalah 11,33 dan 11,5 mm. Hasil uji KLT menunjukkan adanya senyawa alkaloid, flavonoid, dan tanin. Hasil bioautografi tidak menunjukkan adanya aktivitas antibakteri.
Co-Authors Cita Hanif Muflihah Dewi, Meilenia Shinta Kusuma Hanjani, Wildanoor Sekar Hidayah Karuniawati Muhayaroh, Miftah Salsabila, Aulia Shafa Saskia, Adinda Tri Prabandari