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Analysis of Risk Factors that Influence Patient Compliance in Taking Antiretroviral Drugs for HIV/AIDS Treatment in Hanoi Hospital, Vietnam Pham Uyen; Mariette Jackson
Scientific Journal of Dermatology and Venereology Vol. 2 No. 2 (2024): Scientific Journal of Dermatology and Venereology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjdv.v2i1.132

Abstract

Introduction: HIV/AIDS infection remains a global public health problem, with antiretroviral therapy (ARV) being key in its management. Patient adherence to ARV treatment is critical to achieving viral suppression and preventing drug resistance. This study aims to analyze the risk factors that influence patient compliance in taking ARV drugs at Hanoi Hospital, Vietnam. Methods: This study used a cross-sectional analytical observational design involving 300 HIV/AIDS patients undergoing ARV therapy at Hanoi Hospital. Data was collected through structured interviews and patient medical records. Data analysis used logistic regression to identify risk factors associated with patient compliance. Results: The research results showed that the level of patient compliance with ARV treatment was 72%. Risk factors that are significantly associated with patient compliance are: Low social support (OR=2.3; p=0.02), Limited knowledge about HIV/AIDS and ARV treatment (OR=1.8; p=0.04), Stigma and discrimination related to HIV/ AIDS (OR=1.7; p=0.03), Severe side effects of ARV drugs (OR=1.6; p=0.03), Complexity of ARV treatment regimens (OR=1.5; p=0.04). Conclusion: This study found that patient adherence to ARV treatment at Hanoi Hospital was influenced by various factors, including social support, knowledge about HIV/AIDS and ARVs, stigma and discrimination, drug side effects, and the complexity of the treatment regimen. Interventions targeting these risk factors may help improve patient compliance and achieve more optimal treatment outcomes.
Microinvasive Dentistry: A Comparative Study of Resin Infiltration vs. Conventional Methods for Managing Early Caries Lesions in Surabaya, Indonesia Firman Hadi; Abu Bakar; Mariette Jackson; Aprilia Sari
Crown: Journal of Dentistry and Health Research Vol. 1 No. 2 (2023): Crown: Journal of Dentistry and Health Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/crown.v1i2.59

Abstract

Introduction: Early caries lesions are increasingly prevalent, demanding minimally invasive treatment modalities. This study compared the efficacy of resin infiltration and conventional methods in managing early caries lesions in Surabaya, Indonesia. Methods: A randomized controlled clinical trial was conducted involving 120 patients with early caries lesions. Participants were randomly assigned to three groups: resin infiltration, microabrasion, and fluoride varnish application. Lesion characteristics were assessed at baseline, 6, 12, and 24 months using ICDAS criteria and DIAGNOdent readings. Results: Resin infiltration demonstrated significantly higher success rates in arresting lesion progression compared to microabrasion and fluoride varnish at all follow-up periods (p<0.05). Lesion depth and DIAGNOdent values decreased significantly in all groups, with the most significant reduction observed in the resin infiltration group. Conclusion: Resin infiltration proved to be a superior minimally invasive technique for managing early caries lesions compared to conventional methods. Its ability to effectively arrest lesion progression and improve aesthetics highlights its potential as a valuable treatment option in contemporary clinical practice.