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All Journal Paediatrica Indonesiana Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Indonesian Journal of Global Health research Narra J
Muara Lubis
Universitas Sumatera Utara
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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Delayed cord clamping for prevention of iron deficiency anemia in term infants Olga Rasiyanti Siregar; Bugis Lubis; Muara Lubis; Bidasari Lubis; Guslihan Dasa Tjipta
Paediatrica Indonesiana Vol 52 No 4 (2012): July 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (110.655 KB) | DOI: 10.14238/pi52.4.2012.223-8

Abstract

Background Iron deficiency childhood is a concern due to its potentially detrimental effectson development, some of which may be irreversible even after irontreatment. Delayed cord clamping may prevent IDA by increasingan infant's iron reserve at birth.Objective We aimed to evaluate the effect of delayed umbilicalcord clamping at birth on the iron status in newborns at age 24hours of life.Methods This randomized, single􀁒blind study was conducted fromMarch to May 2009, at two general hospitals in Medan, NorthSumatera Province. Eligible newborn infants were randomlyassigned to one of two groups: early cord clamping (Eee)performed 15 seconds after delivery or delayed cord clamping(DeC) performed 2 minutes after delivery. Infants were placed ontheir mothers' abdomens before the umbilical cords were clamped.Hematologic status was determined from umbilical cord blood.Results Sixty􀁒three subjects were included in our study, consistingof31 infants in the Eee group and 32 infants in the Dec group.We found that mean neonatal hemoglobin level was higher inthe Dec group than in the Eee group ( 18.4 g% and 16.2 g%,respectively, P=O.OOOl). Also, mean ferritin level was higher inthe Dec group than in the Eee group (556 mg/dL and 329 mg/dL, respectively, p=o.o 15). Other hematological status indicators,including mean hematocrit and mean corpuscular volume (MeV)level, were also higher in the Dec group. However, mean redblood cell levels were not significantly groups. Nor was there a significant level between the Dec and Eee groups.Concl usion Dela y ed cord c l a m p i n g m a y improve ironstatus and prevent IDA in term infants. [Paediatr Indones.2012;52:223-8].
Quality of Life and Sexual Function of Placenta Accreta Spectrum Disorder Patients after Surgery Muara P. Lubis; Melvin N.G. Barus; M Rizki Yaznil; Edwin M. Asroel; Irwin L. Lumbanraja
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 2 April 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i2.1493

Abstract

Objective: To evaluate sexual function and quality of life features using two validated Female Sexual Function Index (FSFI) questionnaires, and the Short-Form Health Survey (SF-36) in patients with sexually active on Placenta Accreta Spectrum (PAS) Disorder patient.Method: This research is a cross sectional analytic observational study which was conducted in Haji Adam Malik General Hospital from January 2017 - December 2019. Thirty-five study patients who have been diagnosed with PAS disorder and have been treated for at least 3 months were divided into hysterectomy and conservative groups. This study data consisted of primary data from interviews and secondary data from medical records. Independent T test is used if it is normally distributed and Mann-Whitney is used if it is not normally distributed, and it is declared significant if the P value is <0.05. Result: From 8 assessment variables in the SF-36 questionnaire by comparing the questionnaire scores of PASD patients in the hysterectomy and conservative groups by showing significant results on social function (P value 0.021). Whereas in the FSFI questionnaire, there were 6 variables to assess the sexual function of patients with pain variable showing significant results (P value 0.007).Conclusion: There were differences in quality of life (social function) and sexual function (pain) in PASD patients in the hysterectomy and conservative groups.Keywords: Female Sexual Functional Index, Placenta Accreta Spectrum, Quality of Life, Short-Form Health Survey. Abstrak Tujuan: Untuk mengevaluasi fungsi seksual dan fitur kualitas hidup dengan menggunakan dua kuesioner tervalidasi Female Sexual Function Index (FSFI), dan Short-Form Health Survey (SF-36) pada pasien dengan placenta accrete spectrum (PAS) disorder yang aktif secara seksual setelah tindakan operasi.Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode potong lintang yang dilaksanakan di Rumah Sakit Umum Haji Adam Malik dari January 2017-December 2019. Tiga puluh lima pasien yang didiagnosis dengan plasenta akreta spectrum dan telah ditatalaksana minimal 3 bulan dibagi menjadi kelompok histerektomi and konservatif. Data penelitian ini terdiri atas data primer dari wawancara dan data sekunder dari rekam medis. Uji T independen digunakan jika berdistribusi normal dan Mann-Whitney digunakan jika tidak berdistribusi normal, serta dinyatakan signifikan jika nilai P <0.05.Hasil: Dari 8 variabel penilaian dalam kuesioner SF-36 dengan membandingkan skor kuesioner pasien PASD pada kelompok histerektomi dan konservatif dengan menunjukkan hasil yang signifikan pada fungsi sosial (nilai P = 0,021). Sedangkan dalam kuesioner FSFI terdapat 6 variabel untuk menilai fungsi seksual pasien dengan variabel nyeri yang menunjukkan hasil yang signifikan (nilai P = 0,007).Kesimpulan: Terdapat perbedaan dalam kualitas hidup (fungsi sosial) dan fungsi seksual (nyeri) pada pasien PASD di kelompok histerektomi dan konservatif. Kata Kunci: female sexual functional index, placenta accreta spectrum, quality of life, short-form health survey.
Predictive biomarkers of preeclampsia severity in a low resource setting: Role of red blood cell indices, NLR, and albumin-to-creatinine ratio Tobing, Immanuel DL.; Lumbanraja, Sarma N.; Lintang, Letta S.; Edwar, Rafli R.; Adenin, Ichwanul; Lubis, Muara P.; Sukatendel, Khairani; Suarthana, Eva
Narra J Vol. 4 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i2.729

Abstract

Preeclampsia (PE), a serious medical condition with substantial maternal and perinatal implications, poses a significant challenge, particularly in high-incidence countries like Indonesia. Red blood cell (RBC) indices, neutrophil-to-lymphocyte ratio (NLR), and microalbuminuria (albumin-to-creatinine ratio (ACR)) may signal systemic inflammation and endothelial dysfunction, recently recognized as potential indicators for diagnosing and predicting disease severity. The aim of this study was to analyze RBC indices, NLR, and ACR changes in women with PE and their potential for predicting disease severity. A cross-sectional study was conducted at multi-center hospitals across Medan, Indonesia, from June 2022 to June 2023. The patients were grouped into PE cases with and without severe features. Demographic characteristics and complications were recorded while blood and urine were tested. The Chi-squared test, Fisher's exact test and Mann-Whitney test were used to determine biomarkers associated with severe PE. A total of 208 PE patients were included in the study (104 patients for each PE with and without severe features). Our data indicated that PE patients with severe features had higher red cell distribution width (18.5% vs 13.7%; p<0.001), NLR (5.66% vs 4.1%; p<0.001), and ACR (755.97 mg/dL vs 468.63 mg/dL; p<0.001) compared to those without severe features. In contrast, the platelet count was lower in severe features than those without (21.9 × 106/µL vs 27.0 × 106/µL; p=0.002). This study highlighted that PE patients with severe features predominantly had higher levels of RDW, NLR, and ACR and lower platelet counts compared to those without severe features. Therefore, basic tests such as complete blood count and urinalysis, which are inexpensive and feasible in primary care settings with limited resources, offer hope as valuable diagnostic biomarkers for pregnant women diagnosed with PE in a low resource setting.
Correlation between LDH, Liver Function, Platelets and Proteinuria in Preeclampsia with Severe Features Shifa, Rifhani Ashilla; Lubis, Muara Panusunan; Lubis, Hilma Putri; Barus, Melvin Nova Gunawanto
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.635

Abstract

Objectives: To identify the relationship between LDH, bilirubin, SGPT, SGOT, and platelets with proteinuria in preeclampsia with severe features patients. Method: This study is an observational analytical with a retrospective cross-sectional design. The samplings contain 70 patients from the medical records of patients who were diagnosed with preeclampsia with severe features at H. Adam Malik Hospital Medan from January 2020 to March 2023.Results: It was found that 74.3% of the population had semiquantitative urine protein levels ≥+2. The average levels of LDH, total bilirubin, SGPT, SGOT, and platelets were 514.64 U/L, 0.9 mg/dL, 57.77 U/L, 64.01 U/L, and 197,585/mm3, respectively. Statistical analysis showed a positive association between proteinuria and LDH (p=0.001). However, there was no meaningful association between liver and platelet function and proteinuria.Conclusion: There is a relationship between LDH and proteinuria in severe preeclampsia patients.Hubungan antara LDH, Fungsi Hati, Trombosit dengan Proteinuria pada Pasien Preeklamsia BeratAbstrakTujuan: Untuk mengidentifikasi hubungan antara LDH, bilirubin, SGPT, SGOT, dan trombosit dengan proteinuria pada pasien preeklampsia dengan gejala berat.Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain potong lintang retrospektif. Sampel terdiri dari 70 pasien dari rekam medis pasien yang didiagnosis dengan preeklampsia berat di RSUP H. Adam Malik Medan pada periode Januari 2020 hingga Maret 2023.Hasil: Ditemukan bahwa 74,3% dari populasi memiliki kadar protein urin semikuantitatif ≥+2. Kadar rata-rata LDH, bilirubin total, SGPT, SGOT, dan trombosit masing-masing adalah 514,64 U/L, 0,9 mg/dL, 57,77 U/L, 64,01 U/L, dan 197.585/mm3. Analisis statistik menunjukkan hubungan positif antara proteinuria dan LDH (p=0,001). Namun, tidak ada hubungan yang bermakna antara fungsi hati dan trombosit dengan proteinuria.Kesimpulan: Terdapat hubungan antara LDH dan proteinuria pada pasien preeklampsia berat.Kata kunci: hemolisis, fungsi hati, trombosit, preeklamsia berat, proteinuria
Cervical Cancer Patient Experiences with Chemotherapy in Conducting Their Role as Wives Rambe, Jamila; Nasution, Siti Saidah; Lubis, Muara Panusunan
Indonesian Journal of Global Health Research Vol 6 No S6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS6.5093

Abstract

Wives who suffer from cervical cancers and receive chemotherapy treatment potentially have the potential to experience a decrease in the reproductive function of the organs so that the role as a wife experiences changes such as impaired gynecological functions which result in nonfulfillment of sexual desires, pain during intercourse, bleeding, emotional disturbances, and fatigue so that the daily activities of cervical cancer sufferers experience a significant decrease. Objective to understand cervical cancer patients' experiences with chemotherapy in conducting their role as wives. the study was a qualitative design with a phenomenological approach. Data were collected using an interview with 8 participants and analyzed using colaizzi. Then, it is transcribed and analyzed repeatedly. The second step, analyzing, is conducted by extracting significant statements, categorizing, and understanding the essential meaning. In the third step, describing, the researcher communicates, concludes, and defines the phenomenon. 6 Themes are found in this research: 1) conducting the role as a wife part, 2) sexual relationship disorders, 3) self –concept disorder 4) anxiety of cancer 5) medication side effects, 6) getting the family support. The study result indicates that despite the side effects of chemotherapy experienced by wives who suffer from cervical cancer, they still can conduct their role as wives supported by the family.
Co-Authors Adenin, Ichwanul Barus, Melvin Nova Gunawanto Bidasari Lubis Bugis Lubis Edwar, Rafli R. Edwin M. Asroel Eva Suarthana Guslihan Dasa Tjipta Hilma Putri Lubis Irwin L. Lumbanraja Lintang, Letta S. Lumbanraja, Sarma N. M Rizki Yaznil Melvin N.G. Barus Nasution, Siti Saidah OLGA RASIYANTI SIREGAR, OLGA RASIYANTI Rambe, Jamila Shifa, Rifhani Ashilla Sukatendel, Khairani Tobing, Immanuel DL.