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All Journal Journal of General Procedural Dermatology and Venereology Indonesia Bali Dermatology Venereology and Aesthetic Journal
Sitohang, Irma Bernadette Simbolon
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Markedly clinical improvement of papulopustular rosacea with multimodality therapeutic approach: a case report Priyanto, Mufqi Handaru; Wardani, Amanda Nandi; Legiawati, Lili; Sitohang, Irma Bernadette Simbolon; Suseno, Lis Surachmiati
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 6, Issue 1 (June 2023)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/85p5m842

Abstract

Introduction: Rosacea is a chronic inflammatory skin disease that mainly affects the central area of the face. There are four subtypes, and they may progress between subtypes or span multiple subtypes. Due to its long course of the disease, optimum treatments are needed to control the disease progression. Case: We reported rapid improvement of combining topical metronidazole, doxycycline, and light emitting diode for treating a patient with papulopustular rosacea in a 44-years-old woman, a week from the initial therapy. Discussion: Therapeutic approaches to rosacea mainly focus on controlling the symptoms with anti-inflammatory agents. More recently, photodynamic therapy, especially light-emitting diodes, has been introduced as a valid alternative or an adjuvant therapy to conventional treatment through their synergic mechanism between therapeutic modalities. Conclusions: This combination treatment may be effective for treating papulopustular rosacea without any side effects.
Comparing Sodium Fusidate and Petrolatum for Electrosurgery-related Wound Healing: A Double-blind Randomized Controlled Trial Parrol, Firman; Wibawa, Larisa Paramitha; Sitohang, Irma Bernadette Simbolon; Saldi, Siti Rizny Fitriana
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Electrosurgery is a common surgical technique used to treat skin tumors. This procedure produces necrotic skin, which might impair the wound healing process, prompting physicians to prescribe topical antibiotics to prevent infection. This study aims to analyze the efficacy of sodium fusidate ointment compared to petrolatum for wound healing after electrosurgery. Methods: We conducted a double-blind, randomized, controlled study with a within-person design. The inclusion criteria were adult subjects with seborrheic keratosis or acrochordon with a size of 4 mm to 10 mm on the face and neck, with a minimum of 2 lesions. Electrodessication was performed on the subject lesions. The patients were then randomized to receive and sodium fusidate ointment or petrolatum. Follow-up was done for up to 14 days, during which wound healing score, erythema, edema, crusts, re-epithelialization, incidence of infection, and subjective symptoms were assessed. This study is registered in ClinicalTrials.gov (NCT05353374). Results: Twenty-two subjects with 90 wounds were enrolled. The subjects had a mean age of 48.18 ± 11.25 years old and 86.4% of them had seborrheic keratosis. Statistical analysis revealed no significant difference in erythema, edema, crusts, re-epithelialization, infection, subjective symptoms, and total wound healing score appearance on days 3, 7, and 14 following the procedure. Conclusion: Both sodium fusidate ointment and petrolatum showed similar efficacy for wound healing after electrosurgery.
Co-Authors Larisa Paramitha Lili Legiawati Parrol, Firman Priyanto, Mufqi Handaru Saldi, Siti Rizny Fitriana Suseno, Lis Surachmiati Wardani, Amanda Nandi