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Fasting and Dietary Restriction Impact on Immune System in Aging Population: A Narrative Review Handayani, Luh Gede Laksmi Rahayu; Rahmawati, Fitriana Nur; Saputri, Dianita Susilo
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 7 No. - (2023): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v7i-.200

Abstract

Dietary habits and nutrition metabolism are strongly associated with human physiology. Overnutrition or calorie excess has been shown to have many deleterious effects. At the same time, the impact of fasting as part of dietary restriction (DR) remains elusive, especially on the immune system during the aging process. Here, we describe current updates of fasting and DR impact on the immune system and host responses in the aging population. Generally, fasting causes alteration in immune cell distribution by increasing the homing of peripheral cells to the bone marrow. In the aging population, fasting reduces the inflammatory response and promotes cell regeneration. Additionally, fasting is associated with the B cell clonal expansions important to counter infection. This review offers new perspectives and enhances our understanding of immunosenescence as a key to healthy aging.
Abses Paru pada COVID-19 Kurniawan, Adi; Khairan, Paramita; Librianty, Nurfanida; Mahrani, Mahrani; Faisal, Hana; Mutmainah, Iffa; Rahmawati, Fitriana Nur; Marwadhani, Sarah Shafa; Adinda, Gadistya Novitri; Sari, Uti Nilam; Prawirohardjo, Pukovisa
Majalah Kedokteran Indonesia Vol 70 No 8 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.8-2020-255

Abstract

Objective: COVID-19 is a new emerging disease since December 2019 that later was announced by WHO as a global pandemic. Radioimaging appearance of COVID-19 is varied yet dominantly showed as a ground glass appearance in CT-imaging. Lung abscess in COVID-19 is an extremely rare case, therefore it needs further discussion. Method: We report a 39 year-old male patient of COVID-19 with lung abscess.Result: This case report describe a COVID-19 patient who showed a very rare clinical manifestation; lung abscess. The patient showed negative result of TB molecular test. Chest tube insertion procedure was performed in this patient who showed an improvement after abscess being drained. Conclusion: Lung abscess may occur in COVID-19. Abscess drainage procedure may improve clinical condition of COVID-19 patient.