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Fasting and Dietary Restriction Impact on Immune System in Aging Population: A Narrative Review Handayani, Luh Gede Laksmi Rahayu; Rahmawati, Fitriana Nur; Saputri, Dianita Susilo
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 7 No. - (2023): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v7i-.200

Abstract

Dietary habits and nutrition metabolism are strongly associated with human physiology. Overnutrition or calorie excess has been shown to have many deleterious effects. At the same time, the impact of fasting as part of dietary restriction (DR) remains elusive, especially on the immune system during the aging process. Here, we describe current updates of fasting and DR impact on the immune system and host responses in the aging population. Generally, fasting causes alteration in immune cell distribution by increasing the homing of peripheral cells to the bone marrow. In the aging population, fasting reduces the inflammatory response and promotes cell regeneration. Additionally, fasting is associated with the B cell clonal expansions important to counter infection. This review offers new perspectives and enhances our understanding of immunosenescence as a key to healthy aging.
Abses Paru pada COVID-19 Kurniawan, Adi; Khairan, Paramita; Librianty, Nurfanida; Mahrani, Mahrani; Faisal, Hana; Mutmainah, Iffa; Rahmawati, Fitriana Nur; Marwadhani, Sarah Shafa; Adinda, Gadistya Novitri; Sari, Uti Nilam; Prawirohardjo, Pukovisa
Majalah Kedokteran Indonesia Vol 70 No 8 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.8-2020-255

Abstract

Objective: COVID-19 is a new emerging disease since December 2019 that later was announced by WHO as a global pandemic. Radioimaging appearance of COVID-19 is varied yet dominantly showed as a ground glass appearance in CT-imaging. Lung abscess in COVID-19 is an extremely rare case, therefore it needs further discussion. Method: We report a 39 year-old male patient of COVID-19 with lung abscess.Result: This case report describe a COVID-19 patient who showed a very rare clinical manifestation; lung abscess. The patient showed negative result of TB molecular test. Chest tube insertion procedure was performed in this patient who showed an improvement after abscess being drained. Conclusion: Lung abscess may occur in COVID-19. Abscess drainage procedure may improve clinical condition of COVID-19 patient.
The Relationship Between Physical Activity and Menstrual Cycles in Urban Adolescents Girls Amelia, Dessy; Novembriani, Rizqie Putri; Puriastuti, Alifia Candra; Rahmawati, Fitriana Nur; Mukharam, Khamdan; Billah, Moh.Andi Arif
Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Vol. 14 No. SI1 (2026): Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Educat
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpk.V14.ISI1.2026.115-123

Abstract

Background: Many adolescents face barriers to physical activity due to sociocultural factors, which may deter them from engaging in regular exercise. Sedentary lifestyles typical of urban adolescents may be associated with increased menstrual irregularities due to factors such as unhealthy weight gain, stress, and poor nutrition, all of which could be exacerbated by low levels of physical activity. This study aims to determine the relationship between physical activity and menstrual regularity in urban adolescents in Malang City. Method: An institutional-based cross-sectional study was conducted on public vocational high school students in Malang City from July until August 2025. The total calculated sample size is 96 respondents. Logistic regression is used to find the relationship between dependent and independent variables. Result: Logistic regression analysis showed that the level of physical activity was not significantly associated with menstrual cycle regularity (p > 0.05 across all activity categories). The Exp(B) value for moderate activity was 1.545 (95% CI: 0.424–5.633) and for high activity was 0.800 (95% CI: 0.247–2.596), indicating no meaningful difference in the likelihood of having a regular menstrual cycle compared to the low physical activity group. Model fit testing revealed Cox & Snell R Square of 0.020 and Nagelkerke R Square of 0.027, suggesting that physical activity explained only about 2–3% of the variation in menstrual cycle regularity. Conclusion: Therefore, physical activity level cannot be considered a significant predictor of menstrual cycle regularity in this study.