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All Journal Bioscientist : Jurnal Ilmiah Biologi SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Tibrani, Masagus Muhammad
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Anti-Inflamatory Effect Of Aquadest Extract Of Mango Ginger Rhizome (Curcuma mangga Val) In Swiss Webster Mice (Mus musculus) Damaryan, Difa; Tibrani, Masagus Muhammad; Riyanto
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 4 No. 2 (2025): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v4i2.141

Abstract

This study aims to determine the effect of aqueous extract of Curcuma mangga Val. rhizome on the anti-inflammatory response in mice (Mus musculus). The study employs an experimental method with a completely randomized design (CRD) consisting of five treatment groups: a negative control (aqueous solution), a positive control (Sodium Diclofenac 0.13 mg/kgBW), and three doses of Curcuma mangga rhizome extract (7 mg/kgBW, 28 mg/kgBW, and 56 mg/kgBW). Each treatment was administered orally 15minutes before induction with 1 % of egg white. The mice's edema volume was measuredevery hour for six hours after inflammation induction using egg white. Data were analyzed using One-Way ANOVA and Duncan's Multiple Range Test (DMRT). The One-Way ANOVA results indicated a significant effect of Curcuma mangga aqueous extract on the anti-inflammatory response, while the DMRT results showed that the 56 mg/kgBW dose had the most significant anti-inflammatory effect, with an edema inhibition percentage of 63%, closely approaching the effectiveness of Sodium Diclofenac at 62%.
Pengembangan Modul Ajar Pencemaran Lingkungan dengan Materi Realitas Lokal Indralaya pada Jenjang SMA Kelas X Anggraini, Nike; Rohmawati, Shofi; Meilinda, Meilinda; Tibrani, Masagus Muhammad
Bioscientist : Jurnal Ilmiah Biologi Vol. 12 No. 1 (2024): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i1.10580

Abstract

This research is a type of development research which aims to develop the Merdeka Curriculum teaching module with material on environmental pollution accompanied by material on the local reality context of Indralaya which is suitable to be donated or used at the class X high school level. This research includes development research (development research) which uses a model ADDIE development consists of 5 stages, namely analysis, design, development, implementation and evaluation, where the evaluation carried out is a formative evaluation. The assessment results from the validators obtained a feasibility score of 85.16% with several suggestions given as well as the conclusion from the two validators that the product being developed could be tested with improvements according to the suggestions. After the development stage, an evaluation stage is carried out, namely by improving it according to suggestions from the validator. The results of trials with students showed that all students who were respondents could understand and read the contents of the teaching module being developed. According to the results obtained, the Merdeka Curriculum teaching module product on environmental pollution along with material on the local reality context of Indralaya has been successfully developed and received a feasibility validation score in the very valid category.
Co-Authors Anggraini, Nike Damaryan, Difa Meilinda Meilinda Riyanto Rohmawati, Shofi