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All Journal Journal of Psychiatry Psychology and Behavioral Research (JPPBR) Jurnal Info Kesehatan
Khoirinda, Ani
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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THE OUTCOMES OF EATING DISORDER BEHAVIOR DURING PREGNANCY Khoirinda, Ani
Journal of Psychiatry Psychology and Behavioral Research Vol. 5 No. 2 (2024): Integration of Mental Health by Review and Clinical Perspectives
Publisher : Departemen Psikiatri Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jppbr.2024.005.02.3

Abstract

Introduction – Eating disorder behavior is a serious mental illness, that is indicated by a person's eating behavior. The eating disorder has several types including anorexia nervosa, bulimia nervosa, binge eating disorder, and eating disorder not otherwise specified. Eating disorders not only occur in adolescents but can also occur in pregnant women. Eating disorders that occur during pregnancy will affect her pregnancy. Methods – The method used is a literature review. From 117 articles, 5 articles were obtained to be analyzed. Articles used for the period 2018-2023. Journal articles, published on PubMed, Europepme, Frontiers, Wiley Online Library, and Google Scholar. Articles are analyzed by looking at, the author, year, and title, researcher goals, design, and results. Results – Eating Disorder during pregnancy is fatal to the outcome of pregnancy. Small for gestational age is more common in mothers with anorexia nervosa. Large for gestational age is more common in mothers with binge eating disorder and bulimia nervosa. The supporting factors that cause eating disorders are the most important are smoking and symptoms of depression and anxiety. Discuss – Pregnant women with eating disorders (AN, BN, BED, and EDNOS) are caused by several strong factors that influence these behaviors, one of which is smoking before and during pregnancy and symptoms of anxiety and depression. Conclusion –Eating disorders in pregnancy produce a large impact on pregnancy outcomes, especially in the fetus, such as LGA, LBW, IUGR, and SGA. The impact that occurs by the fetus can also have an impact until adulthood. Therefore, mothers should be more aware of eating disorder behavior during pregnancy.  Keywords: eating disorder, pregnancy, infant.
The Effect Flavonoids Phaleria macrocarpa Fruit Extract on Thickness of Trabeculae, Cortex Ratio Femoral Bone and Aortic Intima-Media in Mice Menopause Model Fadilah, R. A. Rahmawati Nurul; Khoirinda, Ani; Sutrisno, Sutrisno; Irwanto, Yahya; Anita, Kenty Wantri; Dewi, R. A. Rose Khasana
JURNAL INFO KESEHATAN Vol 22 No 2 (2024): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol22.Iss2.1553

Abstract

A deficiency of the hormone estrogen at menopause can lead to an increased rate of the destruction of the bone tissue that leads to bone loss, which can lead to osteoporosis and impaired fat metabolism, which increases the risk of atherosclerosis. Phytoestrogens from flavonoid extract P. Macrocarpa, having effects similar to endogenous estrogens themselves, prevent osteoporosis and atherosclerosis in menopausal women. The purpose of this research is to assess the influence of flavonoids from P. Macrocarpa fruit extract on trabeculae cortex thickness, ratio of femoral bone, and aortic IMT (A-IMT) in a menopausal mouse model. The study was conducted in a true experimental-posttest-only control group design. Using 32 mice; namely KN (normal mice with no treatment), KP (OVX with no treatment), P1(OVX and given flavonoid 3.75 mg/mice/day), P2 (OVX and given flavonoid 7.5 mg/mice/day), P3(OVX and given flavonoid 11.25 mg/mice/day), P4 (OVX and given flavonoid 15 mg/mice/day), the treatment given within 14 days. Then the thickness of the trabeculae, cortex, and intima-media aorta with Hematoxylin-Eosin (HE) staining. In the trabeculae, cortex thickness ratio obtained KN results meaningfully dissimilar to the KP group and the P3 and P4 groups were meaningfully dissimilar from the KP. The A-BMI in KP is meaningfully dissimilar to P1, P2, P3 and P4. The conclusion of the study is flavonoid fruit extract P. Macrocarpa can increase the thickness ratio of trabeculae, and cortex femoral bone of mice menopausal model in groups P3, P4 and can decrease A-IMT starting in groups P1 to P4.              
The Effect of Flavonoids of Phaleria macrocarpa Fruit Extract on Aortic Diameter Mice Menopause Model Khoirinda, Ani; Fadilah, R. A. Rahmawati Nurul; Sutrisno, Sutrisno; Irwanto, Yahya; Dewi, R. A. Rose Khasana
JURNAL INFO KESEHATAN Vol 22 No 2 (2024): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol22.Iss2.1554

Abstract

Menopause is a phase experienced by women with an age range of 45-55 years. Menopause is a condition where menstruation stops for a minimum of 12 consecutive months due to the decline in ovarian function, leading to a reduction in estrogen levels. A decrease in estrogen can lead to impaired fat metabolism resulting in atherosclerosis. This study aimed to illustrate the influence of flavonoid extract derived from Phaleria Macrocarpa on the enlargement of the aorta's diameter of mice with a menopause condition. The method of this study is a genuine experimental laboratory setting with a research design of a Randomized Post Test Only Control Group setting. Using 32 female mice divided into 6 groups: K- (without ovariectomy and flavonoid extract Phaleria Macrocarpa), K + (ovariectomy without treatment), P1 (ovariectomy + dose 3.75 mg/mice/day), P2 (ovariectomy + dose 7.5 mg/mice/day), P3 (ovariectomy + dose 11.25 mg/mice/day), and P4 (ovariectomy + dose 15 mg/mice/day). Administration of flavonoid extract Phaleria Macrocarpa was carried out for 14 days. Data analysis using statistical analysis. The results showed that in a post-hoc test, namely the administration of Phaleria macrocarpa flavonoid extract at a dose of 11.25 mg/mice/day and 15 mg/mice/day showed that it could increase the dilation of the aortic diameter of mice model menopause. The study concludes that the flavonoid fruit extract from Phaleria Macrocarpa has the ability to increase the width of the aorta in mice with a menopause condition. In future studies, it is recommended to investigate various variables in order to identify the factors that contribute to the narrowing of the aorta. Additionally, it is suggested to perform further research specifically focusing on women going through menopause.
Co-Authors Dewi, Rose Khasana Fadilah, R. A. Rahmawati Nurul Kenty Wantri Anita, Kenty Wantri Sutrisno, Sutrisno Yahya Irwanto