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All Journal Jurnal Kefarmasian Indonesia JMIMAS: Jurnal Pengabdian dan Mitra Masyarakat
Novi Nur Afifah
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Humanities Chemistry Education Medicine & Pharmacology Social Sciences Other

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Chemometric Analysis of Ethanol Extract of Breadfruit Leaves (Artocarpus altilis) from Various Regions in Central Java Yumni, Gharsina Ghaisani; Rini Primitasari; Novi Nur Afifah; Sumantri, Sumantri
Jurnal Kefarmasian Indonesia VOLUME 14, NUMBER 2, AUGUST 2024
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Breadfruit leaves (Artocarpus altilis) contain chemical compounds, including flavonoids, phenolics, tannins, alkaloids, and saponins, which have antioxidant activity. The planting location causes differences in the composition of active compounds, causing their biological activity to change. This research aimed to determine the highest antioxidant activity, flavonoid, phenolic, and tannin content of 96% ethanol extract of breadfruit leaves from 6 sub-districts in Central Java and to group them using the principal component analysis (PCA) and cluster analysis (CA) chemometric methods. Breadfruit leaves were extracted using the maceration method using 96% ethanol solvent. The antioxidant activity test was carried out using the DPPH method using vitamin C as a comparison. Total flavonoid levels were determined using an AlCl3 reagent. Determination of total phenolic and tannin content levels using Folin-Ciocalteu. Then, chemometric analysis was carried out using Principal Component Analysis (PCA) and Cluster Analysis (CA). The results showed that 96% ethanol extract of breadfruit leaves has the highest IC50, flavonoid, phenolic, and tannin levels, respectively, namely 82.79 ± 0.20 µg/ml; 9,96 ± 0,17 mgQE/g; 603.75 ± 2.6; 123.66 ± 0.76 which came from the Tengaran area. The samples were divided into three groups using PCA and CA methods based on the variables used. The first group was Gajahmungkur, Mranggen, and Pamotan. The second group was Gunungpati and Bandungan. The third group was Tengaran.
EDUKASI KESEHATAN MENTAL MELALUI NILAI KEISLAMAN DI MAJELIS TAKLIM MASJID AL-IKHLAS DESA CIMANGGU KABUPATEN CILACAP Sri Mulyani; Kartika Wanojaleni; Novi Nur Afifah; Putri Dhiya Ulhaq; Farchanudin
JMIMAS: JURNAL PENGABDIAN DAN MITRA MASYARAKAT Vol 1 No 03 (2025): JMIMAS: Jurnal Pengabdian dan Mitra Masyarakat
Publisher : Rumah Jurnal INSIMA Cilacap

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Mental health has become an important issue in modern society, including in Indonesia. This article describes a mental health education program based on Islamic values through majelis taklim (Islamic study gatherings) as a means of empowering religious communities. The activities were carried out by a team of volunteers from INSIMA over two months at Masjid Al-Ikhlas Cimanggu, involving 30 participants. The approach used was participatory qualitative with thematic study methods that integrated the spiritual values of fasting and the concept of mental health. The results showed three main achievements: (1) a 90% increase in participants' understanding of the psychological benefits of fasting, (2) the organic growth of a culture of mental health discussions, and (3) the integration of mental health materials into the study curriculum. This program has proven effective in increasing mental health literacy based on Islamic values, strengthening intervention models in religious communities that are relevant to the local socio-cultural context. This finding provides theoretical and practical contributions to national mental health promotion through the synergy between the religious and health sectors.
Co-Authors Farchanudin Gharsina Ghaisani Yumni Kartika Wanojaleni Putri Dhiya Ulhaq Rini Primitasari Sri Mulyani Sumantri Sumantri