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All Journal Jurnal Pendidikan Sains Indonesia (Indonesian Journal of Science Education) Biosaintifika: Journal of Biology & Biology Education
Ramasamy, Sujatha
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Agriculture, Biological Sciences & Forestry Education

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The potency of Elaeocarpus grandiflorus Leaf Extract as Anti-obesity:  in vivo and in silico Study Nugrahaningsih, WH; Ramasamy, Sujatha; Laraswati, Vivi Anggraeni; Yuniastuti, Ari; Christijanti, Wulan
Biosaintifika: Journal of Biology & Biology Education Vol. 16 No. 2 (2024): August 2024
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v16i2.3695

Abstract

The research aims to determine the effect of ethanol extract of Elaeocarpus grandiflorus leaves extract as anti-obesity by in vivo and silico computational models.  The pre-and -post-tests were carried out on 20 female Wistar rats, divided into 4 groups. The control group (K) received no treatment and the experimental groups were treated with E. grandiflorus extract of 200 mg/kg BW (P1), 400 mg/kg BW (P2), and 800 mg/kg BW (P3) for 14 days. The body weight, abdominal circumference, and abdominal fat mass were measured on Day 1 and Day 15. The results showed differences in body weight (p=0.02), abdominal circumference (p=0.01), and abdominal fat mass (p=0.00). In silico exploration, bioactive compounds of rutin, orientin, luteolin, vitexin, iso orientin, isovitexin, kaempferol, and quercetin were identified, and targeted ELAVL1, IGF1R, CREB1, AKT1, and PIK3R1 of the AMPK signaling pathway that involved in the anti-obesity mechanism. The high binding affinity values was rutin-EVAL1 (-9.3), orientin-ELAVL1 (-8.3), and quercetin- IGFR1 (-8.2). It can be concluded that the ethanol extract of E. grandiflorus leaves has the potential to be developed as an anti-obesity agent.
Ethnobotanical Study on Plants Used As Natural Dye by Handwritten Batik Craftsmen in Cirebon Indonesia Jabar, Muhammad Abdul; Rahayu, Enni Suwarsi; Ramasamy, Sujatha
Biosaintifika: Journal of Biology & Biology Education Vol. 16 No. 2 (2024): August 2024
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v16i2.10923

Abstract

Cirebon Regency is one of the few Indonesian batik craft center which still use natural dyes in hand-written batik making. The natural dyes are generally extracted from plants. The kind of plants used as natural dyes source for batik in Cirebon Regency are not yet known. This ethnobotanical research aimed to describe the kinds of plants and their characteristics, the frequency of citation by respondents, the parts of the organs used, the sources of obtaining plants, the colors produced, usage technique, as well as the role of using natural dyes in batik to support implementation of green economy. The research approach was exploratory descriptive through observation and interview techniques for data collection. The research was carried out at Kebon Gedang Block, Ciwaringin Village, Cirebon Regency, Indonesia in September 2023. Thirty respondents were selected by purposive sampling method and subjected to the interview. The results showed there were 14 plants species from 12 families used as natural dyes. The most frequently used species were Mangifera indica and Indigofera tinctoria. The organ most widely used was the bark which comes from the purchased, and the color generally produced was brown. The most frequently coloring method used was boiling technique. This research is the first study in this area and useful for providing data and strategic potential for developing local plants as environmentally friendly natural dyes, as well as supporting efforts to use natural dyes in the batik industry.
Development of Ethnoscience-Based E-Modules on Arabica Java Ijen-Raung Coffee Plant to Improve Learning Outcomes of Grade IV Elementary Students Sofian*, Aulia Dwi Putri; Nuriman, Nuriman; Wardani, Rizki Putri; Ramasamy, Sujatha
Jurnal Pendidikan Sains Indonesia Vol 13, No 1 (2025): JANUARY 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jpsi.v13i1.41524

Abstract

Indonesia is a country that has a rich culture and abundant natural resources. In the globalization era, local cultures are significantly fading due to the incoming influence of foreign cultures. Education is a tool to bridge knowledge and values embedded in a place to the community. Ethnoscience is an approach that connects local culture and scientific knowledge. This study uses an ethnoscience approach to preserve knowledge derived from natural potential in Indonesia. Integrating ethnoscience concepts in learning helps students improve their learning outcomes and master 21st-century skills that are relevant today. This study aims to develop an ethnoscience-based e-module on the arabica java ijen-raung coffee plant. This module highlights the unique methods of planting Arabica coffee in the Ijen highlands. This study examines the validity, effectiveness, and practicality of using an ethnoscience-based e-module on the arabica java ijen-raung coffee plant to improve learning outcomes of grade IV elementary students. This quantitative development research uses the ADDIE model, which contains analysis, design, development, implementation, and evaluation processes. The result of this research shows a 93% validity score. Effectivity score using N-Gain methods earns 79,2822 included in the effective category. Practicality score earns 94% including in excellent category. Based on this result. It can be concluded that the ethnoscience-based e-module on the arabica java ijen-raung coffee plant is valid, effective, and practical to improve student learning outcomes for grade IV elementary school students
Co-Authors Ari Yuniastuti Enni Suwarsi Rahayu Jabar, Muhammad Abdul Laraswati, Vivi Anggraeni Nugrahaningsih, WH Nuriman Nuriman, Nuriman RIZKI PUTRI WARDANI Sofian*, Aulia Dwi Putri Wulan Christijanti