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All Journal Pharmascience Bina Bangsa International Journal of Business and Management
Zakiyah, Nadhira
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Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Medicine & Pharmacology

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INTERNAL AUDIT AS A MANAGEMENT AID TOOL IN SUPPORTING SERVICE IMPLEMENTATION AND HUMAN RESOURCES QUALITY Chaerudin, Abdul Rauf; Zullaiqa, Nabila; Zakiyah, Nadhira
Bina Bangsa International Journal of Business and Management Vol. 3 No. 1 (2023): Bina Bangsa International Journal of Business and Management
Publisher : LPPM Universitas Bina Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46306/bbijbm.v3i1.56

Abstract

Given the limitations of a leader to control and supervise the activities of agencies led management must delegate some authority to his subordinates. Therefore the constraints that arise in the delivery of information on the activities delegated to subordinates. So it takes a part of the independent nature, referred to as internal audit agency. The problem that arises is whether the internal audit role in improving the implementation of quality of service and human resources. Starting from the above description, the authors are interested in discussing this issue with the initial conclusions as follows: "Internal Audit adequately implemented to improve the implementation of Quality Management (quality of service and human resources) Institutions". Object of study is the Banten Police Agency, the author uses descriptive analytical methods and quantitative analysis. The data collection technique is field research and library research. The data obtained and analyzed by comparing the data obtained with the theory. From the results of this research is that the implementation of internal audit is adequate. This proves the existence of independence, competence, audit program, the audit, a report is generated and follow-up. Then the internal audit also play a role in supporting the implementation of Quality of Service and Human Resources for internal audit verification, evaluation and recommendations for the implementation of Quality of Service and Human Resources). Thus, from the above it can be concluded that the presence of adequate internal audit will improve the implementation of Quality of Service and Human Resources
Nanopartikel Sebagai Sistem Penghantaran Oral untuk Low Molecular Weight Heparin (LMWH) dalam Pengobatan Kolitis Ulseratif Zakiyah, Nadhira; Jafar, Garnadi; Patonah, Patonah
Jurnal Pharmascience Vol 12, No 1 (2025): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i1.20144

Abstract

Kolitis ulseratif (UC) adalah suatu penyakit radang usus kronis yang mempengaruhi mukosa kolon dan rektum. UC memiliki etiologi kompleks melibatkan faktor genetik, imunologis, lingkungan, mikrobiota usus, psikososial, dan autoimun. Penggunaan heparin berat molekul rendah (LMWH) dalam terapi UC terbatas karena stabilitas dan bioavailabilitasnya yang rendah ketika diberikan secara oral. Nanopartikel dirancang untuk melindungi LMWH dari degradasi, meningkatkan penargetan ke jaringan yang meradang, dan meningkatkan efisiensi terapeutik obat. Metode yang digunakan merupakan metode deskriptif dengan pendekatan kualitatif melalui studi literatur. Data dikumpulkan dari berbagai database dengan fokus pada artikel yang dipublikasikan antara tahun 2014 hingga 2024. Hasil menunjukkan bahwa nanopartikel berbasis LMWH efektif dalam mengurangi pelepasan sitokin pro-inflamasi dan menargetkan penghantaran obat ke lokasi spesifik dalam saluran pencernaan. Penghantaran oral dengan nanopartikel memberikan stabilitas selama transit gastrointestinal dan melepaskan obat di area usus besar yang meradang, sehingga meningkatkan kepatuhan pasien dan efikasi pengobatan. Sehingga dapat disimpulkan bahwa sistem penghantaran obat berbasis nanopartikel menawarkan pendekatan yang menjanjikan untuk meningkatkan terapi UC, terutama dalam mengatasi keterbatasan pengobatan konvensional. Kata Kunci: Kolitis Ulseratif, LMWH, Oral, Nanopartikel
Co-Authors Abdul Rauf Chaerudin Garnadi Jafar, Garnadi Patonah, Patonah Zullaiqa, Nabila