Aprilia Kadi, Fiva
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Unusual Lifespan of Edwards' Syndrome in COVID-19 Era Suryaningrat, Filla Reviyani; Hudayari, Devatri; Amalda Ediwan, Natasha; Rita Mardhiya, Wan; Aprilia Kadi, Fiva; Primadi, Aris; Yuniati, Tetty
Majalah Kedokteran Bandung Vol 56, No 3 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3230

Abstract

Edwards' syndrome is caused by an extra chromosome on the 18th chromosome. Patients with this diagnosis have median survival of only 3-14.5 days, with the majority of infants with full trisomy 18 type die before or shortly after they are born. There is only supportive treatment available for Edwards’ syndrome. During the COVID-19 pandemic, providing health services was challenging, leading to less than optimum treatments added by patients’ reluctance to visit healthcare facilities due to the fear of COVID-19 transmission. This case study presented an infant with Edwards’ syndrome with major malformation. The patient had several organ problems, was admitted to the NICU, and continued with home care for monitoring for 6 months. Patient then died at 9 months of age. Maintaining the best quality of life for this patient was very challenging for parents and healthcare providers. Since the management for this type of sydnome is more palliative, good education, information, and psychosocial supports for the parents are needed to prepare them with the worst conditions, which was especially more challenging during the COVID-19 pandemic.
A Case Study on Neurological Outcome in Persistent Neonatal Hypoglycemia in Upper Middle-Income Country Primadi, Aris; Yuniati, Tetty; Aprilia Kadi, Fiva; Reviyani Suryaningrat, Filla; Hudayari, Devatri; Ediwan, Natasha Amalda
Majalah Kedokteran Bandung Vol 56, No 4 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3350

Abstract

In Indonesia, comprehensive management and monitoring of persistent neonatal hypoglycemia, is rarely reported. Despite the fact that there are studies highlighting the risk of neurodevelopmental disorders in neonates with hypoglycemia, there seems to be limited comprehensive case reports detailing both the early diagnosis and the long-term growth and development monitoring in these neonates. A unique case report of a 10-day-old male baby, born at a term weeks gestation via caesarean section, diagnosed with persistent hypoglycemia and suspect of hyperinsulinemia is presented in this study. At birth, the neonate exhibited hypoglycemia with a blood glucose level of 25 mg/dL, accompanied by a one-minute seizure characterized by upward gaze and stiffening of the extremities. The neonate cried after seizure and there was no loss of consciousness and was admitted to the NICU due to worsening respiratory distress. Based on the thoracic X-ray examination, he was diagnosed with transient tachypnea of newborn (TTN). Blood glucose levels were monitored every four hours, and tests for cortisol, thyroid and growth hormone and routine urinalysis were planned. Total parenteral nutrition (TPN) were given with intravenous antibiotics. At 6months of age, the infant was diagnosed with intellectual disability by the growth and development social pediatric unit. At 7 months, the infant  began undergoing physiotherapy. This case was followed for 7 months in total and the findings highlight the challenges in managing neonatal persistent hypoglycemia and the potential long-term developmental implications in neonates with early-life hypoglycemia, emphasizing the need for continual growth and development monitoring.
Impact Of Maternal Education On Birth Weight and Gestational Age In West Java: A 2022 Study Aprilia Kadi, Fiva; Pratiwi, Indah Anindya; Rakhmilla, Lulu Eva
Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Vol. 13 No. 2 (2025): Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Educatio
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpk.V13.I2.2025.224-229

Abstract

Infant development is greatly influenced by maternal health. Maternal factors such as level of education and age impact self-care during pregnancy, resulting in heterogeneity of birth weight and gestational age. Objective: This study analyzes the association between maternal level of education and age with birth weight and gestational age. Methods: A cross-sectional study with simple random sampling was performed by using medical records at Dr. Hasan Sadikin General Hospital Bandung from 1st January to 31st December 2019. Subjects were mothers who delivered single live-born and infants without congenital anomalies at Dr. Hasan Sadikin General Hospital Bandung. Data analysis represents the proportion between groups and the Mann-Whitney test (p<0.05) to observe the association between variables. Results: A total of 1574 birth data encounter the criteria in this study. Types of delivery, abnormality of amnion fluid, IUGR, PROM, and pregnancy complications didn’t differ between high- and low-risk groups of mothers. High-risk maternal age (<20 and >35 years old) was associated with gestational age (preterm birth, c=36.59 weeks; p=0.036). Maternal level of education wasn’t associated with gestational age and birth weight, also maternal age wasn’t associated with birth weight (p>0.05). Conclusion: High-risk maternal age (<20 and >35 years old) was associated with gestational age (preterm birth), however, a low level of education (no education, elementary school, and junior high school) wasn't shown to be related. Birth weight wasn't affected by maternal age and level of education. Further studies that account for socioeconomic aspect in regards of education level and birth weight and gestational age are necessary.