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All Journal Majalah Kedokteran Nusantara The Journal Of Medical School
Nasution, Syafrizal
Fakultas Kedokteran USU
Health Professions Medicine & Pharmacology

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Korelasi Kadar Hepsidin dan Reticulocyte Hemoglobin pada Penderita Gagal Ginjal Terminal dengan Hemodialisis Reguler Ginting, Almaycano; Ganie, Ratna Akbari; Nasution, Syafrizal
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 3 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction Anemia is a frequent complication in Chronic Kidney Disease (CKD), especially in End-State Renal Disease (ESRD) undergoing hemodialysis (HD). Reticulocyte Hemoglobin (Ret.He) represents the average value of Hemoglobin (Hb) distribution in reticulocytes and the availability of iron in the process of erythropoiesis. Hepcidin is a hormone that plays a role in the regulation and metabolism of iron. Hepcidin correlation and Ret.He levels in ESRD patients undergoing regular HD is not known clearly. The aim of study is to determine the correlation of hepcidin and Ret.He in ESRD patients undergoing regular HD.Methods This is a cross sectional study that were conducted at H.Adam Malik Hospital, December 2015-March 2016. Subjects were ESRD outpatients undergoing regular HD in Hemodialysis Unit of H. Adam Malik Hospital over 3 months with a frequency of two times per week and signed the informed consent. Spearman correlation test was used for statistical analysisResults The median levels of hepcidin (0.3 ng/ml) and Ret.He (33.6 pg), were found in 31 subjects. There is a weak correlation but insignificant of hepcidin and Ret.He (r = 0.135, p = 0.467).Conclusion There was no correlation of hepcidin and Ret.He in ESRD patients undergoing regular HD.Keywords : Anemia, Hepcidin in End-Stage Renal Disease, Reticulocyte Hemoglobin, ,Regular hemodialysis, iron status
Hubungan Modifikasi Kadar Natrium Dialisat dengan Kualitas Hidup yang Diukur dengan SF-36 pada Pasien Hemodialisis Reguler Siregar, Bangun Tua; Nasution, Syafrizal; Lubis, Abdurrahim R
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 3 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction Regular hemodialysis patients frequently showed fluctuation of quality of life influence by several factors such as anaemia, age, body water volume regulation and nutritional status and others. Sodium dialysate concentration can be regulated by manually and automatically through hemodyalisis machine. The aim of this study was to determine correlation between sodium dialysate modification and Quality of life measured by Short form-36 (SF-36) in hemodialysis patients.Methods This is an experimental study with case-control design. We recruited 54 chronic hemodialysis patients in hemodialysis center at Adam Malik hospital. Blood sample for sodium serum were taken and quality of life measurement by SF -36 questionaire before and after sodium dialysate modification was performed to all subjects. Then to evaluate the difference and correlation.Results Positive significant correlation found in modification group between physical and mental dimension score and sodium dialysate modification with r = 0.864 and r = 0.339.Conclusion There was a significant correlation between Sodium dialysate modification and physical and mental health dimension from quality of life measured in by SF-36 in hemodialysis patients.Keywords :Sodium dialysate modification, Quality of life (SF-36),Hemodialysis
Co-Authors Ginting, Almaycano Lubis, Abdurrahim R Ratna Akbari Ganie, Ratna Akbari Siregar, Bangun Tua