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All Journal Majalah Kedokteran Nusantara The Journal Of Medical School Indonesian Journal of Medicine Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Inspirasi: Jurnal Pengabdian Masyarakat
Ginting, Almaycano
Fakultas Kedokteran USU
Humanities Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Korelasi Kadar Hepsidin dan Reticulocyte Hemoglobin pada Penderita Gagal Ginjal Terminal dengan Hemodialisis Reguler Ginting, Almaycano; Ganie, Ratna Akbari; Nasution, Syafrizal
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 3 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction Anemia is a frequent complication in Chronic Kidney Disease (CKD), especially in End-State Renal Disease (ESRD) undergoing hemodialysis (HD). Reticulocyte Hemoglobin (Ret.He) represents the average value of Hemoglobin (Hb) distribution in reticulocytes and the availability of iron in the process of erythropoiesis. Hepcidin is a hormone that plays a role in the regulation and metabolism of iron. Hepcidin correlation and Ret.He levels in ESRD patients undergoing regular HD is not known clearly. The aim of study is to determine the correlation of hepcidin and Ret.He in ESRD patients undergoing regular HD.Methods This is a cross sectional study that were conducted at H.Adam Malik Hospital, December 2015-March 2016. Subjects were ESRD outpatients undergoing regular HD in Hemodialysis Unit of H. Adam Malik Hospital over 3 months with a frequency of two times per week and signed the informed consent. Spearman correlation test was used for statistical analysisResults The median levels of hepcidin (0.3 ng/ml) and Ret.He (33.6 pg), were found in 31 subjects. There is a weak correlation but insignificant of hepcidin and Ret.He (r = 0.135, p = 0.467).Conclusion There was no correlation of hepcidin and Ret.He in ESRD patients undergoing regular HD.Keywords : Anemia, Hepcidin in End-Stage Renal Disease, Reticulocyte Hemoglobin, ,Regular hemodialysis, iron status
Comparison of Hepcidin Levels in Children with and without Soil-Transmitted Helminths Infection Dewi Saputri; Yunilda Andriyani; Almaycano Ginting
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 26, No 2 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i2.1471

Abstract

Helminths infection is one of the diseases that still occur insociety. The helminth infection caused by theSoil-Transmitted Helminths (STHs) group, which is Ascaris lumbricoides, Trichuris trichiura, and hookworm in human cancause chronic bleeding resulting in decreasir on storage in the body and increased level of hepcidin. Hepcidin is a liverhormone which regulates iron metabolism and can function as marker of inflammation and iron deficiency. This study aimedto compare the hepcidin levels in STH-infected and non-infected children. A cross-sectional study was conducted betweenMay and October 2018 on 28 STH infected and 140 non-infected subjects. The collected stool samples were analyzed usingthe Kato-Katz method to determine the presence of STH infection and the degree of infection. Urine samples wereprocessed, and their hepcidin levels were measured using a Sandwich-ELISA method. Measurement was made using aSpectrophotometer. The difference of numeric variables was analyzed using Wilcoxon test. The prevalence of STH infectionwas 16.66%. The prevalence of Trichuris trichiura 10.71%, Ascaris lumbricoides 4.76% and hookworm 2.97%. The prevalenceof a single infection was 14.88% and mixed infection 1.78%. Based on the intensity of infection, 15.48% of subjects were mildinfection, 0.59% moderate infection, and 0.59% severe infection. Hepcidin levels in the infected and uninfected group didnot differ significantly (p=0.978). There were no different hepcidin levels in children with and without soil-transmittedhelminths infection.
Comparison of Hepcidin Levels in Children with and without Soil-Transmitted Helminths Infection Dewi Saputri; Yunilda Andriyani; Almaycano Ginting
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 26 No. 2 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i2.1471

Abstract

Helminths infection is one of the diseases that still occur insociety. The helminth infection caused by the Soil-Transmitted Helminths (STHs) group, which is Ascaris lumbricoides, Trichuris trichiura, and hookworm in human can cause chronic bleeding resulting in decreasir on storage in the body and increased level of hepcidin. Hepcidin is a liver hormone which regulates iron metabolism and can function as marker of inflammation and iron deficiency. This study aimed to compare the hepcidin levels in STH-infected and non-infected children. A cross-sectional study was conducted betweenMay and October 2018 on 28 STH infected and 140 non-infected subjects. The collected stool samples were analyzed using the Kato-Katz method to determine the presence of STH infection and the degree of infection. Urine samples were processed, and their hepcidin levels were measured using a Sandwich-ELISA method. Measurement was made using a Spectrophotometer. The difference of numeric variables was analyzed using Wilcoxon test. The prevalence of STH infection was 16.66%. The prevalence of Trichuris trichiura 10.71%, Ascaris lumbricoides 4.76% and hookworm 2.97%. The prevalence of a single infection was 14.88% and mixed infection 1.78%. Based on the intensity of infection, 15.48% of subjects were mild infection, 0.59% moderate infection, and 0.59% severe infection. Hepcidin levels in the infected and uninfected group did not differ significantly (p=0.978). There were no different hepcidin levels in children with and without soil-transmitted helminths infection.
PELATIHAN CARA MENCUCI TANGAN UNTUK PENCEGAHAN INFEKSI CACING TULAR TANAH PADA ANAK SEKOLAH DASAR DI SDN 105269 SEI BERAS SEKATA Sinambela, Adelina Haryani; Siahaan , Lambok; Ginting , Almaycano; Saputri , Dewi; Panggabean , Yoan Carolina; Sitorus , Mega Sari
Inspirasi: Jurnal Pengabdian Masyarakat Vol. 1 No. 3 (2024): Inspirasi: Jurnal Pengabdian Masyarakat
Publisher : Inspirasi: Jurnal Pengabdian Masyarakat

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Abstract

Prevalensi infeksi kecacingan tular tanah (STH) di dunia adalah 24% dari populasi dunia dan anak-anak usia sekolah dasar yang tinggal di daerah dengan tingkat penularan yang tinggi mencapai 568 juta jiwa. STH dapat disebabkan oleh termakan telur cacing yang infeksius. Salah satu upaya untuk mencegah STH adalah dengan mempraktikkan kebiasaan mencuci tangan yang benar dengan sabun dan air mengalir. Oleh karena itu, perlu adanya edukasi STH dan pelatihan yang berkesinambungan kepada anak-anak usia sekolah dasar agar dapat menerapkan kebiasaan cuci tangan yang baik dan benar. Target dan hasil: Sebanyak 39 siswa SDN Sei Sekata terlibat dalam kegiatan pengabdian masyarakat ini. Luaran dari kegiatan ini adalah meningkatnya pengetahuan peserta setelah pemberian edukasi dan peserta mampu melaksanakan materi yang diberikan kepada keluarga dan lingkungan sekitarnya. Metode: Kegiatan ini dilakukan dengan memberikan materi edukasi dalam bentuk ceramah dan pemutaran video serta pelatihan cara mencuci tangan yang baik dan benar. Sebelum pemberian edukasi, seluruh peserta diberikan soal pre-test untuk mengetahui tingkat pengetahuan mereka tentang STH dan cara mencuci tangan yang benar. Setelah edukasi, seluruh peserta diberikan soal post-test dengan pertanyaan yang sama. Selanjutnya, kuku para peserta dipotong dan dilakukan cuci tangan.
Correlation between HbA1c Levels and Red Distribution Cell Width in Type 2 Diabetes Mellitus Patients Rahma, Hadiyatur; Siregar, Jelita; Syafril, Santi; Ganie, Ratna Akbari; Siregar, Dewi Indah Sari; Ginting, Almaycano
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.684

Abstract

Background: HbA1c is used as a parameter for diagnosis and monitoring of diabetes mellitus (DM). Apart from that, HbA1c, red blood cells also experience changes which result in changes in erythrocyte structure and hemodynamic characteristics. The parameter that changes in this case is red cell distribution width (RDW). This study aimed to analyze correlation between HbA1c levels and RDW in type 2 DM patients. Subjects and Method: This a cross sectional study conducted at H. Adam Malik General Central Hospital, Medan, North Sumatera, Indonesia, from December 2022-April 2023. Total sample of 75 type 2 DM patients was selected consecutively. The dependent variable was RDW. The independent variable was HbA1c. Data of RDW and HbA1c were collected from complete blood count test. Data were analyzed using the Spearman correlation. Results: HbA1c was negatively associated with RDW, but it was statistically non-significant (r= -0.08; p= 0.508). Conclusion: HbA1c is negatively associated with RDW, but it is statistically non-significant.   Keywords: diabetes melitus, HbA1c, red cell distribution width
Co-Authors Adelina Haryani Sinambela Dewi Saputri Nasution, Syafrizal Panggabean , Yoan Carolina Rahma, Hadiyatur Ratna Akbari Ganie, Ratna Akbari Santi Syafril, Santi Saputri , Dewi Siahaan , Lambok Siregar, Dewi Indah Sari Siregar, Jelita Sitorus, Mega Sari Yunilda Andriyani