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All Journal Pharmaceutical Sciences and Research (PSR) Smart Society Empowerment Journal
Karima, Muzakiya Lailatul
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Evaluation of Anti-VEGF and Pan-Retinal Photocoagulation Laser Therapies in Proliferative Diabetic Retinopathy Patients: A Systematic Review Indrakila, Senyum; Imani, Namira Putri; Asaduddin, Aiman Hilmi; Karima, Muzakiya Lailatul; Widjaja, Lygia Angelica
Pharmaceutical Sciences and Research Vol. 10, No. 2
Publisher : UI Scholars Hub

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Abstract

Diabetic retinopathy is a complication of diabetes that is one of the top five causes of blindness in those over 50. The standard treatment is pan-retinal photocoagulation, which is effective but has established side effects. Anti-vascular endothelial growth factor (anti-VEGF) therapy becomes an alternative to avoid the side effects caused by laser therapy. This systematic review aims to know the effectiveness of anti-VEGF therapy compared to the pan-retinal photocoagulation laser therapy in patients with proliferative diabetic retinopathy. This review was carried out using a systematic review checklist on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). The articles reviewed were randomized controlled trial articles that met the inclusion and exclusion criteria. Based on inclusion and exclusion criteria, six articles were selected from a total of 215. Patients who received anti-VEGF medication had better visual acuity (positive values), whereas patients who received laser therapy had poorer visual acuity (negative values). Those results are because the laser directs light towards the retina, damaging photoreceptors and retinal cells as well as reducing visual acuity. On the contrary, anti-VEGF prevents damage to retinal endothelial cells and blood leaks in the vitreous by decreasing VEGF expression and thus resulting in improved visual acuity. Anti-VEGF proved to be a more practical alternative therapy in improving visual acuity than pan-retinal photocoagulation for patients with proliferative diabetic retinopathy.
Upaya Percepatan Penurunan Stunting Melalui Peningkatan Kesadaran Dan Pengetahuan Masyarakat Terhadap Faktor Risiko Di Desa Jenar, Kabupaten Sragen Karima, Muzakiya Lailatul
Smart Society Empowerment Journal Vol 3, No 1 (2023): Maret
Publisher : Faculty of Medicine, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/ssej.v3i1.65811

Abstract

Introduction: Stunting is a problem that is currently a concern for the Indonesian government because the incidence rate is quite high. In 2021, the stunting incidence rate was obtained at 24.4%. The government is trying to reduce the incidence of stunting to 14% by 2024. In this regard, this community service activity aims to make the stunting reduction acceleration program a success.Methods: This community service activity was carried out in Jenar Village, Jenar District, Sragen Regency, which is one of the stunting focus locations from July 15 to August 12, 2022 with large group counseling methods and interventions to the community in the form of anthropometric measurements and healthy gymnastics.Results and discussions: The participation and attention of mothers in activities is very good, partner groups actively contribute to the procurement of activity needs and actively share experiences about child growth and development and a healthy lifestyle. The impact of counseling activities can increase the knowledge and awareness of the people of Jenar Village regarding the risk factors for stunting and a healthy lifestyle.Conclusion: Community service activities in the context of efforts to accelerate the reduction of stunting in Jenar Village are very useful and are expected to play a role in reducing the incidence of stunting.
Co-Authors Asaduddin, Aiman Hilmi Imani, Namira Putri Senyum Indrakila Widjaja, Lygia Angelica